Form4insider filings, from the source

Company · CIK 0000874015 · SIC 2834 — Pharmaceutical Preparations · Nasdaq

IONIS PHARMACEUTICALS INC · IONS

Insider activity reported against this company. All insider holders · Files at: AKCA, RGLS. On EDGAR ↗

1M3M6M1Y2YAll datashares as filed — not split-adjusted
Open-market activity at this companybuys $1.1M · 1sales $99.1M · 181net −$98.0M
$10k$10k$100k$100k$1M$1M$10M$10MbuyssalesJan 2015Dec 2016Nov 2018Oct 2020Sep 2022Aug 2024Jul 2026
Open-market trades as an insider elsewherebuys $225.0M · 2sales $3.8M · 2net $221.2M
$100k$100k$10M$10M$1B$1BbuyssalesJun 2015Dec 2015Jun 2016Nov 2016May 2017Oct 2017Apr 2018

Reported at this company — common stock

TradeReported (ET)InsiderSharesAvg priceTotalOwned afterΔ stakeFlags
Mar 5, 2015 SForm 4 →Mar 9, 7:27 pm EDTElizabeth L HougenSVP, Finance & CFO28,094$71.57$2,010,8233,387−89.2% plan?
Mar 5, 2015 MForm 4 →Mar 9, 7:27 pm EDTElizabeth L HougenSVP, Finance & CFO28,094$10.50$295,06510,824— plan?
Mar 5, 2015 SForm 4 →Mar 9, 7:27 pm EDTPatrick R. O'NeilSVP, Legal & General Counsel5,800$71.67$415,6746,174−48.4% plan?
Mar 5, 2015 MForm 4 →Mar 9, 7:27 pm EDTPatrick R. O'NeilSVP, Legal & General Counsel5,800$9.63$55,86510,307— plan?
Mar 5, 2015 SForm 4 →Mar 9, 7:26 pm EDTJoseph H WenderDirector12,500$71.61$895,17430,217−29.3% plan?
Mar 5, 2015 MForm 4 →Mar 9, 7:26 pm EDTJoseph H WenderDirector12,500$9.77$122,12542,717— plan?
Mar 5, 2015 SForm 4 →Mar 9, 7:25 pm EDTJoseph Klein IIIDirector7,000$70.95$496,6824,095−63.1% plan?
Mar 5, 2015 MForm 4 →Mar 9, 7:25 pm EDTJoseph Klein IIIDirector10,000$10.18$101,80011,095— plan?
Mar 2, 2015 SForm 4 →Mar 4, 7:15 pm ESTJoseph H WenderDirector7,000$65.97$461,78530,217−18.8% plan?
Feb 12, 2015 SForm 4 →Feb 17, 5:39 pm ESTJoseph H WenderDirector10,000$62.15$621,46037,217−21.2% plan?
Feb 12, 2015 MForm 4 →Feb 17, 5:39 pm ESTJoseph H WenderDirector10,000$3.95$39,50047,217— plan?
Feb 11, 2015 GForm 4 →Feb 13, 5:50 pm ESTJoseph Klein IIIDirector2,000——1,095— plan?
Feb 3, 2015 MForm 4 →Feb 5, 6:08 pm ESTJoseph LoscalzoDirector938——938— plan?
Jan 27, 2015 SForm 4 →Jan 29, 7:03 pm ESTStanley T CrookeChairman and CEO, Director11,000$72.93$802,1861,297−89.5% plan?
Jan 27, 2015 MForm 4 →Jan 29, 7:03 pm ESTStanley T CrookeChairman and CEO, Director11,000$11.08$121,9202,297— plan?
Jan 16, 2015 SForm 4 →Jan 20, 8:00 pm ESTStanley T CrookeChairman and CEO, Director9,054$67.96$615,3481,297−87.5% plan?
Jan 16, 2015 SForm 4 →Jan 20, 7:58 pm ESTB Lynne ParshallCOO & Secretary, Director4,093$67.96$278,1778,072−33.6% plan?
Jan 16, 2015 SForm 4 →Jan 20, 7:57 pm ESTBrett P MoniaSVP, Antisense Drug Discovery1,534$67.96$104,2574,426−25.7% plan?
Jan 16, 2015 SForm 4 →Jan 20, 7:57 pm ESTElizabeth L HougenSVP, Finance & CFO1,291$67.96$87,7423,387−27.6% plan?
Jan 16, 2015 SForm 4 →Jan 20, 7:56 pm ESTPatrick R. O'NeilSVP, Legal & General Counsel1,291$67.96$87,7426,174−17.3% plan?
Jan 16, 2015 SForm 4 →Jan 20, 7:55 pm ESTC Frank BennettSVP, Antisense Research1,518$67.96$103,1697,229−17.4% plan?
Jan 16, 2015 SForm 4 →Jan 20, 7:53 pm ESTRichard S GearySVP, Development1,543$67.96$104,8687,570−16.9% plan?
Jan 15, 2015 MForm 4 →Jan 20, 8:00 pm ESTStanley T CrookeChairman and CEO, Director17,425——1,433— plan?
Jan 15, 2015 MForm 4 →Jan 20, 7:58 pm ESTB Lynne ParshallCOO & Secretary, Director7,748——9,890— plan?
Jan 15, 2015 MForm 4 →Jan 20, 7:57 pm ESTBrett P MoniaSVP, Antisense Drug Discovery4,025——5,140— plan?
Jan 15, 2015 MForm 4 →Jan 20, 7:57 pm ESTElizabeth L HougenSVP, Finance & CFO3,383——4,101— plan?
Jan 15, 2015 MForm 4 →Jan 20, 7:56 pm ESTPatrick R. O'NeilSVP, Legal & General Counsel3,383——6,888— plan?
Jan 15, 2015 MForm 4 →Jan 20, 7:55 pm ESTC Frank BennettSVP, Antisense Research3,984——7,943— plan?
Jan 15, 2015 MForm 4 →Jan 20, 7:53 pm ESTRichard S GearySVP, Development4,049——8,284— plan?
Jan 12, 2015 SForm 4 →Jan 13, 6:49 pm ESTRichard S GearySVP, Development597$73.10$43,6415,064−10.5% plan?
Jan 9, 2015 SForm 4 →Jan 13, 6:51 pm ESTStanley T CrookeChairman and CEO, Director11,000$73.57$809,270627−94.6% plan?
Jan 9, 2015 MForm 4 →Jan 13, 6:51 pm ESTStanley T CrookeChairman and CEO, Director11,000$11.08$121,9201,627— plan?
Jan 6, 2015 SForm 4 →Jan 8, 7:15 pm ESTStanley T CrookeChairman and CEO, Director22,000$67.04$1,474,946627−97.2% plan?
Jan 6, 2015 MForm 4 →Jan 8, 7:15 pm ESTStanley T CrookeChairman and CEO, Director22,000$11.08$243,8401,627— plan?
Jan 2, 2015 SForm 4 →Jan 5, 8:04 pm ESTB Lynne ParshallCOO & Secretary, Director11,200$62.12$695,6884,417−71.7% plan?
Jan 2, 2015 SForm 4 →Jan 5, 8:03 pm ESTPatrick R. O'NeilSVP, Legal & General Counsel1,500$62.12$93,1734,082−26.9% plan?
Jan 2, 2015 SForm 4 →Jan 5, 7:56 pm ESTBrett P MoniaSVP, Antisense Drug Discovery76$62.75$4,7691,935−3.78% plan?
Jan 1, 2015 JMForm 4 →Jan 5, 8:04 pm ESTB Lynne ParshallCOO & Secretary, Director11,311$14.84$167,86315,617— plan?
Jan 1, 2015 JMForm 4 →Jan 5, 8:03 pm ESTPatrick R. O'NeilSVP, Legal & General Counsel1,829$13.73$25,1054,365— plan?
Jan 1, 2015 JForm 4 →Jan 5, 8:01 pm ESTElizabeth L HougenSVP, Finance & CFO63$30.05$1,8931,295— plan?
Jan 1, 2015 JForm 4 →Jan 5, 7:59 pm ESTC Frank BennettSVP, Antisense Research136$30.05$4,0864,763— plan?
Jan 1, 2015 JForm 4 →Jan 5, 7:57 pm ESTRichard S GearySVP, Development273$30.05$8,2035,661— plan?
Jan 1, 2015 JForm 4 →Jan 5, 7:56 pm ESTBrett P MoniaSVP, Antisense Drug Discovery198$30.05$5,9492,011— plan?

Reported at this company — derivatives (options, RSUs, warrants)

TradeReported (ET)InsiderSharesAvg priceTotalOwned afterΔ stakeFlags
Dec 15, 2015 MForm 4 →Dec 17, 7:23 pm ESTC Frank BennettSVP, Antisense Research7,909——0—
Dec 1, 2015 MForm 4 →Dec 2, 6:49 pm ESTPatrick R. O'NeilSVP, Legal & General Counsel1,000——2,067—
Nov 11, 2015 MForm 4 →Nov 12, 7:02 pm ESTJoseph Klein IIIDirector6,875——2,812—
Nov 10, 2015 MForm 4 →Nov 12, 7:03 pm ESTC Frank BennettSVP, Antisense Research5,000——7,909—
Nov 9, 2015 GForm 4 →Nov 9, 7:45 pm ESTB Lynne ParshallCOO & Secretary, Director8,000——1,000—
Nov 6, 2015 MForm 4 →Nov 9, 7:28 pm ESTC Frank BennettSVP, Antisense Research5,000——12,909—
Nov 3, 2015 MForm 4 →Nov 4, 7:00 pm ESTPatrick R. O'NeilSVP, Legal & General Counsel1,000——3,067—
Oct 21, 2015 MForm 4 →Oct 23, 7:35 pm EDTStanley T CrookeChairman and CEO, Director44,000——2,000—
Oct 1, 2015 MForm 4 →Oct 5, 7:14 pm EDTB Lynne ParshallCOO & Secretary, Director12,436——29,354—
Jul 6, 2015 MForm 4 →Jul 8, 5:55 pm EDTB Lynne ParshallCOO & Secretary, Director6,218——17,027—
Jul 6, 2015 MForm 4 →Jul 8, 5:54 pm EDTStanley T CrookeChairman and CEO, Director6,175——5,000—
Jul 1, 2015 MForm 4 →Jul 2, 6:06 pm EDTB Lynne ParshallCOO & Secretary, Director6,218——1,375—
Jul 1, 2015 MForm 4 →Jul 2, 6:02 pm EDTStanley T CrookeChairman and CEO, Director6,175——6,175—
Jul 1, 2015 AMForm 4 →Jul 2, 6:00 pm EDTJoseph H WenderDirector20,115——16,000—
Jul 1, 2015 AMForm 4 →Jul 2, 6:00 pm EDTFrederick T MutoDirector20,115——16,000—
Jul 1, 2015 AMForm 4 →Jul 2, 5:59 pm EDTJoseph LoscalzoDirector19,334——16,000—
Jul 1, 2015 AMForm 4 →Jul 2, 5:58 pm EDTJoseph Klein IIIDirector20,115——16,000—
Jul 1, 2015 AMForm 4 →Jul 2, 5:57 pm EDTBreaux CastlemanDirector20,741——16,000—
Jul 1, 2015 AMForm 4 →Jul 2, 5:57 pm EDTSpencer R BerthelsenDirector20,115——16,000—
Jun 8, 2015 MForm 4 →Jun 10, 6:36 pm EDTBrett P MoniaSVP, Antisense Drug Discovery7,600——0—
Jun 1, 2015 MForm 4 →Jun 3, 5:29 pm EDTFrederick T MutoDirector10,000——0—
Apr 17, 2015 MForm 4 →Apr 17, 6:13 pm EDTSpencer R BerthelsenDirector10,000——0—
Apr 7, 2015 MForm 4 →Apr 8, 5:12 pm EDTB Lynne ParshallCOO & Secretary, Director5,565——37,628—
Apr 7, 2015 MForm 4 →Apr 8, 5:11 pm EDTStanley T CrookeChairman and CEO, Director22,377——7,350—
Apr 1, 2015 MForm 4 →Apr 6, 11:51 am EDTB Lynne ParshallCOO & Secretary, Director5,377——43,193—
Apr 1, 2015 MForm 4 →Apr 6, 11:50 am EDTStanley T CrookeChairman and CEO, Director21,623——9,384—
Mar 23, 2015 MForm 4 →Mar 25, 4:23 pm EDTC Frank BennettSVP, Antisense Research15,000——17,909—
Mar 19, 2015 MForm 4 →Mar 20, 6:58 pm EDTElizabeth L HougenSVP, Finance & CFO10,000——10,000—
Mar 19, 2015 MForm 4 →Mar 20, 6:56 pm EDTRichard S GearySVP, Development8,000——17,240—
Mar 19, 2015 MForm 4 →Mar 20, 6:55 pm EDTPatrick R. O'NeilSVP, Legal & General Counsel30,525——31,875—
Mar 18, 2015 MForm 4 →Mar 20, 6:57 pm EDTJoseph H WenderDirector12,500——0—
Mar 5, 2015 MForm 4 →Mar 9, 7:45 pm EDTRichard S GearySVP, Development15,080——7,035—
Mar 5, 2015 MForm 4 →Mar 9, 7:27 pm EDTElizabeth L HougenSVP, Finance & CFO28,094——4,063—
Mar 5, 2015 MForm 4 →Mar 9, 7:27 pm EDTPatrick R. O'NeilSVP, Legal & General Counsel5,800——1,617—
Mar 5, 2015 MForm 4 →Mar 9, 7:26 pm EDTJoseph H WenderDirector12,500——0—
Mar 5, 2015 MForm 4 →Mar 9, 7:25 pm EDTJoseph Klein IIIDirector10,000——5,937—
Feb 12, 2015 MForm 4 →Feb 17, 5:39 pm ESTJoseph H WenderDirector10,000——0—
Feb 3, 2015 MForm 4 →Feb 5, 6:08 pm ESTJoseph LoscalzoDirector938——2,812—
Jan 27, 2015 MForm 4 →Jan 29, 7:03 pm ESTStanley T CrookeChairman and CEO, Director11,000——11,350—
Jan 15, 2015 AMForm 4 →Jan 20, 8:00 pm ESTStanley T CrookeChairman and CEO, Director46,375——1,062—
Jan 15, 2015 AForm 4 →Jan 20, 7:59 pm ESTSarah BoyceChief Business Officer8,750——8,750—
Jan 15, 2015 AMForm 4 →Jan 20, 7:58 pm ESTB Lynne ParshallCOO & Secretary, Director29,824——10,312—
Jan 15, 2015 AMForm 4 →Jan 20, 7:57 pm ESTBrett P MoniaSVP, Antisense Drug Discovery10,095——5,625—
Jan 15, 2015 AMForm 4 →Jan 20, 7:57 pm ESTElizabeth L HougenSVP, Finance & CFO8,901——5,625—
Jan 15, 2015 AMForm 4 →Jan 20, 7:56 pm ESTPatrick R. O'NeilSVP, Legal & General Counsel8,625——5,625—
Jan 15, 2015 AMForm 4 →Jan 20, 7:55 pm ESTC Frank BennettSVP, Antisense Research9,226——5,625—
Jan 15, 2015 AMForm 4 →Jan 20, 7:53 pm ESTRichard S GearySVP, Development9,567——5,625—
Jan 9, 2015 MForm 4 →Jan 13, 6:51 pm ESTStanley T CrookeChairman and CEO, Director11,000——12,350—
Jan 6, 2015 MForm 4 →Jan 8, 7:15 pm ESTStanley T CrookeChairman and CEO, Director22,000——13,350—
Jan 2, 2015 AMForm 4 →Jan 5, 8:04 pm ESTB Lynne ParshallCOO & Secretary, Director143,658——48,570—
Jan 2, 2015 AMForm 4 →Jan 5, 8:03 pm ESTPatrick R. O'NeilSVP, Legal & General Counsel32,957——9,750—
Jan 2, 2015 AMForm 4 →Jan 5, 8:02 pm ESTStanley T CrookeChairman and CEO, Director173,700——8,700—
Jan 2, 2015 AForm 4 →Jan 5, 8:01 pm ESTElizabeth L HougenSVP, Finance & CFO33,112——33,112—
Jan 2, 2015 AForm 4 →Jan 5, 7:59 pm ESTC Frank BennettSVP, Antisense Research31,457——31,457—
Jan 2, 2015 AForm 4 →Jan 5, 7:57 pm ESTRichard S GearySVP, Development33,112——33,112—
Jan 2, 2015 AForm 4 →Jan 5, 7:56 pm ESTBrett P MoniaSVP, Antisense Drug Discovery36,423——36,423—
Jan 1, 2015 AForm 4 →Jan 5, 8:31 pm ESTSarah BoyceChief Business Officer52,500——52,500—

Filed by this entity as an insider elsewhere — common stock

TradeReported (ET)CompanySharesAvg priceTotalOwned afterΔ stakeFlags
Oct 17, 2018 JForm 4 →Oct 18, 8:05 pm EDTAKCEA THERAPEUTICS, INC.AKCA1,671,849——67,383,965— plan?
Aug 3, 2018 JForm 4 →Aug 6, 5:17 pm EDTAKCEA THERAPEUTICS, INC.AKCA1,597,571——65,712,116— plan?
Apr 17, 2018 PForm 4 →Apr 19, 6:48 pm EDTAKCEA THERAPEUTICS, INC.AKCA10,666,666$18.75$199,999,98864,114,545+20.0% plan?
Apr 17, 2018 JForm 4 →Apr 19, 6:48 pm EDTAKCEA THERAPEUTICS, INC.AKCA8,000,000——53,447,879— plan?
Jul 19, 2017 PForm 4 →Jul 21, 4:04 pm EDTAKCEA THERAPEUTICS, INC.AKCA3,125,000$8.00$25,000,00045,447,879+7.38% plan?
Jul 19, 2017 CJForm 4 →Jul 21, 4:04 pm EDTAKCEA THERAPEUTICS, INC.AKCA42,322,879——42,322,879— plan?
Jul 15, 2015 SForm 4 →Jul 17, 6:08 pm EDTRegulus Therapeutics Inc.RGLS343,133$10.60$3,636,0785,173,172−6.22% plan?
Jun 30, 2015 SForm 4 →Jul 2, 4:28 pm EDTRegulus Therapeutics Inc.RGLS13,248$10.79$143,0105,516,305−0.24% plan?
Jun 23, 2015 GForm 4 →Jul 2, 4:28 pm EDTRegulus Therapeutics Inc.RGLS13,248——5,529,553— plan? late

Filed by this entity as an insider elsewhere — derivatives (options, RSUs, warrants)

TradeReported (ET)CompanySharesAvg priceTotalOwned afterΔ stakeFlags
Jul 19, 2017 CForm 4 →Jul 21, 4:04 pm EDTAKCEA THERAPEUTICS, INC.AKCA28,884,540——0—