Form4insider filings, from the source

Company · CIK 0000874015 · SIC 2834 — Pharmaceutical Preparations · Nasdaq

IONIS PHARMACEUTICALS INC · IONS

Insider activity reported against this company. All insider holders · Files at: AKCA, RGLS. On EDGAR ↗

1M3M6M1Y2YAll datashares as filed — not split-adjusted

Reported at this company — common stock

TradeReported (ET)InsiderSharesAvg priceTotalOwned afterΔ stakeFlags
Aug 31, 2026 JForm 4 →Sep 2, 8:32 pm EDTC Frank BennettEVP, Chief Scientific Officer110$51.31$5,64460,128—
Aug 31, 2026 JForm 4 →Sep 2, 8:22 pm EDTPatrick R. O'NeilEVP CLO & General Counsel63$51.31$3,23259,205—
Aug 31, 2026 JForm 4 →Sep 2, 8:22 pm EDTBrett P MoniaChief Executive Officer, Director98$51.31$5,028242,760—
Aug 31, 2026 JForm 4 →Sep 2, 8:22 pm EDTBrian BirchlerEVP, Corp and Development Ops58$51.31$2,976102,883—

Reported at this company — derivatives (options, RSUs, warrants)

No reported derivative activity in this period.

Filed by this entity as an insider elsewhere — common stock

No reported common-stock activity in this period.

Filed by this entity as an insider elsewhere — derivatives (options, RSUs, warrants)

No reported derivative activity in this period.