Company · CIK 0001636282 · SIC 2834 — Pharmaceutical Preparations · Nasdaq
Spyre Therapeutics, Inc. · SYRE
Insider activity reported against this company. All insider holders · On EDGAR ↗
Reported at this company — common stock
| Trade | Reported (ET) | Insider | Shares | Avg price | Total | Owned after | Δ stake | Flags |
|---|---|---|---|---|---|---|---|---|
| Sep 1, 2026 SForm 4 → | Sep 3, 9:34 pm EDT | Heidy King-JonesSee Remarks | 28,399 | $87.35 | $2,480,529 | 2,845 | −90.9% | 10b5-1 |
| Sep 1, 2026 MForm 4 → | Sep 3, 9:34 pm EDT | Heidy King-JonesSee Remarks | 28,399 | $14.50 | $411,786 | 3,245 | — | 10b5-1 |
| Sep 1, 2026 SForm 4 → | Sep 3, 9:33 pm EDT | Scott L BurrowsChief Financial Officer | 25,732 | $88.75 | $2,283,821 | 79,762 | −24.4% | 10b5-1 |
| Sep 1, 2026 MForm 4 → | Sep 3, 9:33 pm EDT | Scott L BurrowsChief Financial Officer | 7,500 | $14.50 | $108,750 | 105,494 | — | 10b5-1 |
| Sep 1, 2026 SForm 4 → | Sep 3, 9:33 pm EDT | Cameron TurtleChief Executive Officer, Director | 15,000 | $87.29 | $1,309,410 | 552,540 | −2.64% | 10b5-1 |
| Aug 7, 2026 SForm 4 → | Aug 10, 9:31 pm EDT | Jeffrey W. AlbersDirector | 23,000 | $104.53 | $2,404,190 | 9,360 | −71.1% | 10b5-1 |
| Aug 7, 2026 MForm 4 → | Aug 10, 9:31 pm EDT | Jeffrey W. AlbersDirector | 5,000 | $10.39 | $51,950 | 5,000 | — | 10b5-1 |
| Aug 3, 2026 SForm 4 → | Aug 5, 9:32 pm EDT | Scott L BurrowsChief Financial Officer | 7,500 | $95.57 | $716,771 | 97,994 | −7.11% | 10b5-1 |
| Aug 3, 2026 MForm 4 → | Aug 5, 9:32 pm EDT | Scott L BurrowsChief Financial Officer | 7,500 | $14.50 | $108,750 | 105,494 | — | 10b5-1 |
| Aug 3, 2026 SForm 4 → | Aug 5, 9:31 pm EDT | Cameron TurtleChief Executive Officer, Director | 15,000 | $95.51 | $1,432,705 | 567,540 | −2.57% | 10b5-1 |
| Jul 1, 2026 SForm 4 → | Jul 2, 9:33 pm EDT | Scott L BurrowsChief Financial Officer | 7,500 | $87.74 | $658,040 | 97,994 | −7.11% | 10b5-1 |
| Jul 1, 2026 MForm 4 → | Jul 2, 9:33 pm EDT | Scott L BurrowsChief Financial Officer | 7,500 | $14.50 | $108,750 | 105,494 | — | 10b5-1 |
| Jul 1, 2026 SForm 4 → | Jul 2, 9:33 pm EDT | Sheldon SloanChief Medical Officer | 8,334 | $87.70 | $730,896 | 0 | −100% | 10b5-1 |
| Jul 1, 2026 MForm 4 → | Jul 2, 9:33 pm EDT | Sheldon SloanChief Medical Officer | 8,334 | $27.46 | $228,852 | 8,334 | — | 10b5-1 |
| Jul 1, 2026 SForm 4 → | Jul 2, 9:32 pm EDT | Cameron TurtleChief Executive Officer, Director | 15,000 | $87.69 | $1,315,346 | 582,540 | −2.51% | 10b5-1 |
| Jun 25, 2026 SForm 4 → | Jun 26, 9:31 pm EDT | Scott L BurrowsChief Financial Officer | 15,000 | $87.13 | $1,307,000 | 97,994 | −13.3% | |
| Jun 25, 2026 MForm 4 → | Jun 26, 9:31 pm EDT | Scott L BurrowsChief Financial Officer | 15,000 | $14.50 | $217,500 | 112,994 | — | |
| Jun 23, 2026 SForm 4 → | Jun 23, 9:56 pm EDT | Fairmount Funds Management LLC +3Director | 4,684,781 | $85.31 | $399,658,667 | 0 | −100% | |
| Jun 23, 2026 CForm 4 → | Jun 23, 9:56 pm EDT | Fairmount Funds Management LLC +3Director | 666,680 | — | — | 4,684,781 | — | |
| Jun 22, 2026 SForm 4 → | Jun 23, 9:32 pm EDT | Michael Thomas HendersonDirector | 20,000 | $100.00 | $2,000,000 | 68,606 | −22.6% | 10b5-1 |
| Jun 3, 2026 SForm 4 → | Jun 3, 9:32 pm EDT | Sheldon SloanChief Medical Officer | 8,333 | $75.00 | $624,975 | 0 | −100% | 10b5-1 |
| Jun 3, 2026 MForm 4 → | Jun 3, 9:32 pm EDT | Sheldon SloanChief Medical Officer | 8,333 | $27.46 | $228,824 | 8,333 | — | 10b5-1 |
| Jun 1, 2026 SForm 4 → | Jun 3, 9:31 pm EDT | Cameron TurtleChief Executive Officer, Director | 15,000 | $70.43 | $1,056,486 | 597,540 | −2.45% | 10b5-1 |
| Jun 1, 2026 SForm 4 → | Jun 3, 9:30 pm EDT | Scott L BurrowsChief Financial Officer | 7,500 | $71.06 | $532,937 | 97,994 | −7.11% | 10b5-1 |
| Jun 1, 2026 MForm 4 → | Jun 3, 9:30 pm EDT | Scott L BurrowsChief Financial Officer | 7,500 | $14.50 | $108,750 | 105,494 | — | 10b5-1 |
Reported at this company — derivatives (options, RSUs, warrants)
| Trade | Reported (ET) | Insider | Shares | Avg price | Total | Owned after | Δ stake | Flags |
|---|---|---|---|---|---|---|---|---|
| Sep 1, 2026 MForm 4 → | Sep 3, 9:34 pm EDT | Heidy King-JonesSee Remarks | 28,399 | — | — | 511,411 | — | 10b5-1 |
| Sep 1, 2026 MForm 4 → | Sep 3, 9:33 pm EDT | Scott L BurrowsChief Financial Officer | 7,500 | — | — | 337,357 | — | 10b5-1 |
| Aug 7, 2026 MForm 4 → | Aug 10, 9:31 pm EDT | Jeffrey W. AlbersDirector | 5,000 | — | — | 45,000 | — | 10b5-1 |
| Aug 3, 2026 MForm 4 → | Aug 5, 9:32 pm EDT | Scott L BurrowsChief Financial Officer | 7,500 | — | — | 344,857 | — | 10b5-1 |
| Jul 1, 2026 MForm 4 → | Jul 2, 9:33 pm EDT | Scott L BurrowsChief Financial Officer | 7,500 | — | — | 352,357 | — | 10b5-1 |
| Jul 1, 2026 MForm 4 → | Jul 2, 9:33 pm EDT | Sheldon SloanChief Medical Officer | 8,334 | — | — | 305,000 | — | 10b5-1 |
| Jun 25, 2026 MForm 4 → | Jun 26, 9:31 pm EDT | Scott L BurrowsChief Financial Officer | 15,000 | — | — | 359,857 | — | |
| Jun 23, 2026 CForm 4 → | Jun 23, 9:56 pm EDT | Fairmount Funds Management LLC +3Director | 16,667 | — | — | 0 | — | |
| Jun 3, 2026 MForm 4 → | Jun 3, 9:32 pm EDT | Sheldon SloanChief Medical Officer | 8,333 | — | — | 313,334 | — | 10b5-1 |
| Jun 1, 2026 MForm 4 → | Jun 3, 9:30 pm EDT | Scott L BurrowsChief Financial Officer | 7,500 | — | — | 374,857 | — | 10b5-1 |