Insider holders · CIK 0001636282
Spyre Therapeutics, Inc. · SYRE
Every insider with a reported Table I holding at this company, ranked by their last-reported share count. A balance is only as fresh as its filing — the report date sits next to every row on purpose. ← Back to activity
| Insider | Direct shares | Indirect shares | Total reported | Last report (ET) | From |
|---|---|---|---|---|---|
| Novartis Bioventures Ltd10% Owner | 2,175,314 | — | 2,175,314 | May 14, 2018 · 4:01 pm EDT | Form 4 |
| NOVARTIS AG10% Owner | 2,175,314 | — | 2,175,314 | May 14, 2018 · 4:01 pm EDT | Form 4 |
| Armen ShanafeltDirector | 57,619 | 2,068,543 | 2,126,162 | Apr 14, 2016 · 7:35 pm EDT | Form 4/A |
| Lilly Ventures Fund I LLC10% Owner | 57,619 | 2,068,543 | 2,126,162 | Apr 14, 2016 · 7:35 pm EDT | Form 4/A |
| LILLY ELI & CO10% Owner | — | 2,068,543 | 2,068,543 | Apr 14, 2016 · 7:35 pm EDT | Form 4/A |
| OrbiMed Capital GP V LLC10% Owner | — | 1,469,524 | 1,469,524 | Feb 21, 2017 · 5:58 pm EST | Form 4 |
| ORBIMED ADVISORS LLC10% Owner | — | 1,469,524 | 1,469,524 | Feb 21, 2017 · 5:58 pm EST | Form 4 |
| Samuel D Isaly10% Owner | — | 1,469,524 | 1,469,524 | Feb 21, 2017 · 5:58 pm EST | Form 4 |
| Cameron TurtleChief Executive Officer | 552,540 | — | 552,540 | Sep 3, 2026 · 9:33 pm EDT | Form 4 |
| Tomas KiselakDirector | — | 406,038 | 406,038 | Jun 23, 2026 · 9:56 pm EDT | Form 4 |
| Fairmount Funds Management LLCDirector | — | 406,038 | 406,038 | Jun 23, 2026 · 9:56 pm EDT | Form 4 |
| Fairmount Healthcare Fund II L.P.Director | — | 406,038 | 406,038 | Jun 23, 2026 · 9:56 pm EDT | Form 4 |
| Peter Evan HarwinDirector | — | 406,038 | 406,038 | Jun 23, 2026 · 9:56 pm EDT | Form 4 |
| George GeorgiouDirector | 175,861 | 165,000 | 340,861 | Aug 15, 2018 · 4:40 pm EDT | Form 4 |
| Anthony G. QuinnPresident & CEO | 276,433 | — | 276,433 | Feb 8, 2019 · 4:15 pm EST | Form 4 |
| David George LoweCEO and President | 206,382 | 5,658 | 212,040 | Apr 12, 2016 · 5:07 pm EDT | Form 4 |
| Scott L BurrowsChief Financial Officer | 79,762 | — | 79,762 | Sep 3, 2026 · 9:33 pm EDT | Form 4 |
| Michael Thomas HendersonDirector | 68,606 | — | 68,606 | Jun 23, 2026 · 9:32 pm EDT | Form 4 |
| S. Edward Torres10% Owner | 57,619 | — | 57,619 | Apr 6, 2016 · 7:52 pm EDT | Form 3 |
| Charles N York IIChief Financial Officer and VP | 34,787 | 11,560 | 46,347 | Dec 5, 2017 · 9:07 pm EST | Form 4 |
| Joseph E TylerVP, Manufacturing | 42,428 | — | 42,428 | Apr 12, 2016 · 5:13 pm EDT | Form 4 |
| Scott W RowlinsonVP, Research | 16,749 | 11,204 | 27,953 | Apr 12, 2016 · 5:12 pm EDT | Form 4 |
| Jeffrey W. AlbersDirector | 0 | 9,360 | 9,360 | Aug 10, 2026 · 9:31 pm EDT | Form 4 |
| Russell J. CoxDirector | 7,000 | — | 7,000 | Apr 12, 2016 · 5:06 pm EDT | Form 4 |
| Heidy King-JonesSee Remarks | 2,845 | — | 2,845 | Sep 3, 2026 · 9:34 pm EDT | Form 4 |
| Aaron SchuchartChief Business Officer | 2,500 | — | 2,500 | Sep 28, 2018 · 5:11 pm EDT | Form 4 |
| Sheldon SloanChief Medical Officer | 0 | — | 0 | Jul 2, 2026 · 9:33 pm EDT | Form 4 |
Balances come from each insider’s most recent filing that reports a Table I holding; an insider who left the company years ago still appears with their last-known figure and its date. Indirect totals collapse multiple vehicles (trusts, LLCs) into one number — open the filing for the breakdown. Shares as filed, not split-adjusted.