Company · CIK 0001420565 · SIC 2834 — Pharmaceutical Preparations · Nasdaq

AILERON THERAPEUTICS INC · ALRN

Insider activity reported against this company. All insider holders · On EDGAR ↗

Period1M 3M 6M 1Y 2Y All datashares as filed — not split-adjusted

Open-market buys & salesbuys $32.8M · 17sales $3.6M · 19net $29.2M

Reported at this company — common stock

Trade	Reported (ET)	Insider	Shares	Avg price	Total	Owned after	Δ stake	Flags
Aug 20, 2018 SForm 4 →	Aug 22, 4:34 pm EDT	Novartis Bioventures Ltd +110% Owner	20,388	$2.30	$46,892	2,396,882	−0.84%	plan?
Aug 16, 2018 SForm 4 →	Aug 20, 5:12 pm EDT	Novartis Bioventures Ltd +110% Owner	17,508	$2.10	$36,767	2,417,270	−0.72%	plan?
Aug 14, 2018 SForm 4 →	Aug 16, 4:18 pm EDT	Novartis Bioventures Ltd +110% Owner	5,935	$2.21	$13,123	2,434,778	−0.24%	plan?
Aug 10, 2018 PForm 4 →	Aug 14, 7:38 pm EDT	John P Longenecker Ph.D.President and CEO	10,000	$2.45	$24,500	10,000	—	plan?
Aug 10, 2018 SForm 4 →	Aug 14, 5:05 pm EDT	Novartis Bioventures Ltd +110% Owner	7,215	$2.42	$17,477	2,440,713	−0.29%	plan?
Aug 8, 2018 SForm 4 →	Aug 10, 4:29 pm EDT	Novartis Bioventures Ltd +110% Owner	1,235	$2.72	$3,363	2,447,928	−0.05%	plan?
Aug 6, 2018 SForm 4 →	Aug 8, 4:21 pm EDT	Novartis Bioventures Ltd +110% Owner	4,681	$3.00	$14,050	2,449,163	−0.19%	plan?
Aug 2, 2018 SForm 4 →	Aug 6, 4:22 pm EDT	Novartis Bioventures Ltd +110% Owner	4,702	$3.33	$15,658	2,453,844	−0.19%	plan?
Jul 31, 2018 SForm 4 →	Aug 2, 4:33 pm EDT	Novartis Bioventures Ltd +110% Owner	12,681	$3.17	$40,158	2,458,546	−0.51%	plan?
Jul 27, 2018 SForm 4 →	Jul 31, 4:16 pm EDT	Novartis Bioventures Ltd +110% Owner	8,458	$3.35	$28,368	2,471,227	−0.34%	plan?
Jul 25, 2018 SForm 4 →	Jul 27, 4:21 pm EDT	Novartis Bioventures Ltd +110% Owner	20,397	$3.76	$76,658	2,479,685	−0.82%	plan?
Jul 23, 2018 SForm 4 →	Jul 25, 4:35 pm EDT	Novartis Bioventures Ltd +110% Owner	31,300	$4.25	$132,927	2,500,082	−1.24%	plan?
Jul 16, 2018 SForm 4 →	Jul 18, 4:17 pm EDT	Novartis Bioventures Ltd +110% Owner	12,800	$4.72	$60,420	2,531,382	−0.50%	plan?
Jul 6, 2018 JForm 4 →	Jul 10, 4:27 pm EDT	Apple Tree Partners II - Annex, L.P.10% Owner	655,797	—	—	0	—	plan?
Jul 6, 2018 JForm 4 →	Jul 10, 4:26 pm EDT	APPLE TREE PARTNERS II LP10% Owner	1,380,241	—	—	0	—	plan?
Jun 22, 2018 SForm 4 →	Jun 26, 6:15 pm EDT	APPLE TREE PARTNERS II LP10% Owner	106,257	$5.92	$629,522	1,380,241	−7.15%	plan?
Jun 20, 2018 SForm 4 →	Jun 21, 9:36 pm EDT	APPLE TREE PARTNERS II LP10% Owner	6,647	$5.30	$35,233	1,486,498	−0.45%	plan?
Jun 15, 2018 SForm 4 →	Jun 19, 5:30 pm EDT	APPLE TREE PARTNERS II LP10% Owner	9,532	$5.32	$50,743	1,493,145	−0.63%	plan?
Jun 12, 2018 SForm 4 →	Jun 14, 5:01 pm EDT	APPLE TREE PARTNERS II LP10% Owner	10,843	$5.40	$58,558	1,502,677	−0.72%	plan?
Jun 8, 2018 PForm 4 →	Jun 12, 5:31 pm EDT	Donald DoughertySVP & Chief Financial Officer	3,000	$5.40	$16,200	5,000	+150%	plan?
Jun 7, 2018 SForm 4 →	Jun 11, 6:51 pm EDT	APPLE TREE PARTNERS II LP10% Owner	28,162	$5.41	$152,315	1,513,520	−1.83%	plan?
Jun 6, 2018 PForm 4 →	Jun 8, 5:14 pm EDT	Manuel AivadoSee Remarks	1,000	$5.61	$5,610	1,000	—	plan?
Jun 1, 2018 PForm 4 →	Jun 4, 4:54 pm EDT	Donald DoughertySVP & Chief Financial Officer	2,000	$5.24	$10,480	2,000	—	plan?
Apr 17, 2018 SForm 4 →	Apr 19, 6:20 pm EDT	APPLE TREE PARTNERS II LP10% Owner	107,904	$6.31	$681,390	1,541,682	−6.54%	plan?
Jan 9, 2018 SForm 4 →	Jan 11, 4:49 pm EST	APPLE TREE PARTNERS II LP10% Owner	150,000	$9.80	$1,470,435	1,649,586	−8.34%	plan?
Jul 5, 2017 PForm 4/A →	Aug 14, 2018, 4:35 pm EDT	Scott KapnickDirector, 10% Owner	66,666	$15.00	$999,990	66,666	—	plan?
Jul 5, 2017 CForm 4 →	Jul 7, 8:31 pm EDT	Apple Tree Partners II - Annex, L.P.10% Owner	655,797	—	—	655,797	—	plan?
Jul 5, 2017 CForm 4 →	Jul 7, 8:24 pm EDT	APPLE TREE PARTNERS II LP10% Owner	1,799,335	—	—	1,799,586	—	plan?
Jul 5, 2017 PForm 4 →	Jul 7, 7:18 pm EDT	Armen ShanafeltDirector	250,000	$15.00	$3,750,000	1,094,987	+29.6%	plan?
Jul 5, 2017 CForm 4 →	Jul 7, 7:18 pm EDT	Armen ShanafeltDirector	844,987	—	—	844,987	—	plan?
Jul 5, 2017 PForm 4 →	Jul 7, 7:16 pm EDT	LV Management Group, LLC +3Other	250,000	$15.00	$3,750,000	1,094,987	+29.6%	plan?
Jul 5, 2017 CForm 4 →	Jul 7, 7:16 pm EDT	LV Management Group, LLC +3Other	844,987	—	—	844,987	—	plan?
Jul 5, 2017 PForm 4 →	Jul 7, 7:13 pm EDT	AJU IB Investment Co., Ltd.10% Owner	24,929	$15.00	$373,935	517,558	+5.06%	plan?
Jul 5, 2017 CForm 4 →	Jul 7, 7:13 pm EDT	AJU IB Investment Co., Ltd.10% Owner	492,629	—	—	492,629	—	plan?
Jul 5, 2017 PForm 4 →	Jul 6, 6:26 pm EDT	Brian M. Gallagher Jr.Director	273,333	$15.00	$4,099,995	1,431,519	+23.6%	plan?
Jul 5, 2017 CForm 4 →	Jul 6, 6:26 pm EDT	Brian M. Gallagher Jr.Director	1,158,186	—	—	1,158,186	—	plan?
Jul 5, 2017 PForm 4 →	Jul 6, 6:25 pm EDT	Sigma Emerging Markets Ltd.10% Owner	190,000	$15.00	$2,850,000	423,086	+81.5%	plan?
Jul 5, 2017 CForm 4 →	Jul 6, 6:25 pm EDT	Sigma Emerging Markets Ltd.10% Owner	233,086	—	—	233,086	—	plan?
Jul 5, 2017 PForm 4 →	Jul 6, 6:16 pm EDT	EXCEL MEDICAL FUND LP +410% Owner	60,000	$15.00	$900,000	1,016,100	+6.28%	plan?
Jul 5, 2017 CForm 4 →	Jul 6, 6:16 pm EDT	EXCEL MEDICAL FUND LP +410% Owner	956,100	—	—	956,100	—	plan?
Jul 5, 2017 PForm 4 →	Jul 6, 6:14 pm EDT	Muneer A Satter10% Owner	33,333	$15.00	$499,995	178,106	+23.0%	plan?
Jul 5, 2017 CForm 4 →	Jul 6, 6:14 pm EDT	Muneer A Satter10% Owner	144,773	—	—	144,773	—	plan?
Jul 5, 2017 PForm 4 →	Jul 5, 8:28 pm EDT	KCK LTD.10% Owner	200,000	$15.00	$3,000,000	646,817	+44.8%	plan?
Jul 5, 2017 CForm 4 →	Jul 5, 8:28 pm EDT	KCK LTD.10% Owner	446,817	—	—	446,817	—	plan?
Jul 5, 2017 CForm 4 →	Jul 5, 8:28 pm EDT	Jon B. Platt10% Owner	90,218	—	—	90,318	—	plan?
Jul 5, 2017 PForm 4 →	Jul 5, 8:27 pm EDT	ROCHE HOLDING LTD +110% Owner	119,400	$15.00	$1,791,000	702,363	+20.5%	plan?
Jul 5, 2017 CForm 4 →	Jul 5, 8:27 pm EDT	ROCHE HOLDING LTD +110% Owner	579,093	—	—	582,963	—	plan?
Jul 5, 2017 PForm 4 →	Jul 5, 8:26 pm EDT	CVF, LLC10% Owner	180,000	$15.00	$2,700,000	716,180	+33.6%	plan?
Jul 5, 2017 CForm 4 →	Jul 5, 8:26 pm EDT	CVF, LLC10% Owner	536,180	—	—	536,180	—	plan?
Jul 5, 2017 PForm 4 →	Jul 5, 8:25 pm EDT	Scott KapnickDirector, 10% Owner	225,973	$15.00	$3,389,595	521,049	+76.6%	plan? amended
Jul 5, 2017 CForm 4 →	Jul 5, 8:25 pm EDT	Scott KapnickDirector, 10% Owner	285,438	—	—	295,076	—	plan? amended
Jul 5, 2017 PForm 4 →	Jul 5, 6:13 pm EDT	Reinhard J. AmbrosDirector	266,667	$15.00	$4,000,005	2,544,182	+11.7%	plan?
Jul 5, 2017 CForm 4 →	Jul 5, 6:13 pm EDT	Reinhard J. AmbrosDirector	2,277,515	—	—	2,277,515	—	plan?
Jul 5, 2017 PForm 4 →	Jul 5, 6:05 pm EDT	Novartis Bioventures Ltd +110% Owner	266,667	$15.00	$4,000,005	2,544,182	+11.7%	plan?
Jul 5, 2017 CForm 4 →	Jul 5, 6:05 pm EDT	Novartis Bioventures Ltd +110% Owner	2,277,515	—	—	2,277,515	—	plan?

Reported at this company — derivatives (options, RSUs, warrants)

Trade	Reported (ET)	Insider	Shares	Avg price	Total	Owned after	Δ stake	Flags
Feb 25, 2019 AForm 4 →	Feb 25, 5:51 pm EST	Kathryn GregorySVP, Chief Business Officer	100,000	—	—	100,000	—
Nov 5, 2018 AForm 4 →	Nov 6, 6:18 pm EST	Vojo VukovicSVP, Chief Medical Officer	150,000	—	—	150,000	—
Sep 6, 2018 AForm 4 →	Sep 7, 5:47 pm EDT	Manuel AivadoPresident and CEO, Director	232,914	—	—	232,914	—
Jun 21, 2018 AForm 4 →	Jun 25, 6:48 pm EDT	Jodie Pope MorrisonDirector	10,000	—	—	10,000	—
Jun 21, 2018 AForm 4 →	Jun 25, 6:25 pm EDT	Armen ShanafeltDirector	10,000	—	—	10,000	—
Jun 21, 2018 AForm 4 →	Jun 25, 6:20 pm EDT	Jeffrey Allen BaileyDirector	10,000	—	—	10,000	—
Jun 21, 2018 AForm 4 →	Jun 25, 6:16 pm EDT	Reinhard J. AmbrosDirector	10,000	—	—	10,000	—
Jun 21, 2018 AForm 4 →	Jun 25, 6:13 pm EDT	Caleb Maxfield WinderDirector	10,000	—	—	10,000	—
Jun 21, 2018 AForm 4 →	Jun 25, 6:12 pm EDT	John H McArthurDirector	10,000	—	—	10,000	—
May 15, 2018 AForm 4 →	May 17, 6:16 pm EDT	John P Longenecker Ph.D.President and CEO	30,000	—	—	30,000	—
Mar 15, 2018 AForm 4 →	Mar 19, 4:06 pm EDT	Jeffrey Allen BaileyDirector	20,000	—	—	20,000	—
Sep 26, 2017 AForm 4 →	Sep 28, 6:20 pm EDT	Reinhard J. AmbrosDirector	20,000	—	—	20,000	—
Jul 25, 2017 AForm 4 →	Jul 27, 6:42 pm EDT	Kira NelsonSee Remarks	36,844	—	—	36,844	—
Jul 25, 2017 AForm 4 →	Jul 27, 6:37 pm EDT	John H McArthurDirector	20,000	—	—	20,000	—
Jul 25, 2017 AForm 4 →	Jul 27, 6:36 pm EDT	Manuel AivadoSee Remarks	57,388	—	—	57,388	—
Jul 25, 2017 AForm 4 →	Jul 27, 6:35 pm EDT	Joseph A., Yanchik IIISee Remarks, Director	157,449	—	—	157,449	—
Jul 25, 2017 AForm 4 →	Jul 27, 6:34 pm EDT	Donald DoughertySVP & Chief Financial Officer	60,331	—	—	60,331	—
Jul 25, 2017 AForm 4 →	Jul 27, 6:30 pm EDT	Armen ShanafeltDirector	20,000	—	—	20,000	—
Jul 25, 2017 AForm 4 →	Jul 27, 6:29 pm EDT	Caleb Maxfield WinderDirector	20,000	—	—	20,000	—
Jul 25, 2017 AForm 4 →	Jul 27, 6:29 pm EDT	Scott KapnickDirector	20,000	—	—	20,000	—
Jul 25, 2017 AForm 4 →	Jul 27, 6:29 pm EDT	Jodie Pope MorrisonDirector	20,000	—	—	20,000	—
Jul 25, 2017 AForm 4 →	Jul 27, 6:27 pm EDT	Brian M. Gallagher Jr.Director	20,000	—	—	20,000	—
Jul 5, 2017 CForm 4 →	Jul 7, 8:31 pm EDT	Apple Tree Partners II - Annex, L.P.10% Owner	6,516,660	—	—	0	—
Jul 5, 2017 CForm 4 →	Jul 7, 8:24 pm EDT	APPLE TREE PARTNERS II LP10% Owner	19,558,842	—	—	0	—
Jul 5, 2017 CForm 4 →	Jul 7, 7:18 pm EDT	Armen ShanafeltDirector	8,396,641	—	—	0	—
Jul 5, 2017 CForm 4 →	Jul 7, 7:16 pm EDT	LV Management Group, LLC +3Other	8,396,641	—	—	0	—
Jul 5, 2017 CForm 4 →	Jul 7, 7:13 pm EDT	AJU IB Investment Co., Ltd.10% Owner	4,895,266	—	—	0	—
Jul 5, 2017 CForm 4 →	Jul 6, 6:26 pm EDT	Brian M. Gallagher Jr.Director	11,508,898	—	—	0	—
Jul 5, 2017 CForm 4 →	Jul 6, 6:25 pm EDT	Sigma Emerging Markets Ltd.10% Owner	2,316,176	—	—	0	—
Jul 5, 2017 CForm 4 →	Jul 6, 6:16 pm EDT	EXCEL MEDICAL FUND LP +410% Owner	9,500,768	—	—	0	—
Jul 5, 2017 CForm 4 →	Jul 6, 6:14 pm EDT	Muneer A Satter10% Owner	1,438,611	—	—	0	—
Jul 5, 2017 CForm 4 →	Jul 5, 8:28 pm EDT	KCK LTD.10% Owner	4,440,023	—	—	0	—
Jul 5, 2017 CForm 4 →	Jul 5, 8:28 pm EDT	Jon B. Platt10% Owner	896,500	—	—	0	—
Jul 5, 2017 CForm 4 →	Jul 5, 8:27 pm EDT	ROCHE HOLDING LTD +110% Owner	5,754,448	—	—	0	—
Jul 5, 2017 CForm 4 →	Jul 5, 8:26 pm EDT	CVF, LLC10% Owner	5,328,027	—	—	0	—
Jul 5, 2017 CForm 4 →	Jul 5, 8:25 pm EDT	Scott KapnickDirector, 10% Owner	2,836,400	—	—	0	—	amended
Jul 5, 2017 CForm 4 →	Jul 5, 6:13 pm EDT	Reinhard J. AmbrosDirector	22,631,671	—	—	0	—
Jul 5, 2017 CForm 4 →	Jul 5, 6:05 pm EDT	Novartis Bioventures Ltd +110% Owner	22,631,671	—	—	0	—
Jun 28, 2017 AForm 4 →	Jun 30, 1:32 pm EDT	Donald DoughertySVP & Chief Financial Officer	140,887	—	—	140,887	—