Company · CIK 0001048477 · SIC 2834 — Pharmaceutical Preparations · Nasdaq

BIOMARIN PHARMACEUTICAL INC · BMRN

Insider activity reported against this company. All insider holders · On EDGAR ↗

Period1M 3M 6M 1Y 2Y All datashares as filed — not split-adjusted

Open-market buys & salesbuys $0 · 0sales $219.8M · 189net −$219.8M

Reported at this company — common stock

Trade	Reported (ET)	Insider	Shares	Avg price	Total	Owned after	Δ stake	Flags
Dec 14, 2017 GForm 4/A →	Feb 20, 2018, 8:33 pm EST	Jean Jacques BienaimeChief Executive Officer, Director	600	—	—	182,201	—	plan?
Dec 14, 2017 SForm 4 →	Dec 18, 8:56 pm EST	Elaine J HeronDirector	800	$88.90	$71,116	38,385	−2.04%	plan?
Nov 30, 2017 SForm 4 →	Dec 4, 8:26 pm EST	George Eric DavisEVP, General Counsel	1,200	$85.64	$102,767	82,942	−1.43%	plan?
Nov 22, 2017 GForm 5 →	Feb 14, 2018, 8:38 pm EST	George Eric DavisEVP, General Counsel	200	—	—	82,742	—	plan?
Oct 31, 2017 AForm 5 →	Feb 14, 2018, 8:30 pm EST	Brian MuellerSVP, Corporate Controller	33	$69.78	$2,303	12,918	—	plan?
Oct 31, 2017 AForm 5 →	Feb 14, 2018, 8:23 pm EST	Daniel K SpiegelmanEVP, Chief Financial Officer	162	$69.78	$11,304	57,600	—	plan?
Sep 29, 2017 AForm 4 →	Oct 3, 8:11 pm EDT	Robert J. HombachDirector	3,180	—	—	3,180	—	plan?
Sep 28, 2017 SForm 4 →	Oct 2, 9:07 pm EDT	Robert BaffiEVP, Technical Operations	18,415	$92.43	$1,702,031	28,761	−39.0%	plan?
Sep 26, 2017 GMForm 4 →	Jan 2, 2018, 5:29 pm EST	Jean Jacques BienaimeChief Executive Officer, Director	21,030	$38.59	$771,800	235,894	—	plan? late
Sep 22, 2017 SForm 4 →	Sep 26, 7:19 pm EDT	Jeffrey Robert AjerEVP, Chief Commercial Officer	3,521	$95.00	$334,495	47,944	−6.84%	plan?
Sep 22, 2017 MForm 4 →	Sep 26, 7:19 pm EDT	Jeffrey Robert AjerEVP, Chief Commercial Officer	3,521	$37.46	$131,897	50,110	—	plan?
Sep 15, 2017 SForm 4 →	Sep 19, 3:27 pm EDT	V Bryan LawlisDirector	3,750	$91.26	$342,225	15,910	−19.1%	plan?
Sep 15, 2017 MForm 4 →	Sep 19, 3:27 pm EDT	V Bryan LawlisDirector	3,750	$38.59	$144,713	19,660	—	plan?
Sep 15, 2017 SForm 4 →	Sep 19, 3:17 pm EDT	Henry J FuchsPresident, Worldwide R&D	15,000	$90.50	$1,357,500	136,422	−9.91%	plan?
Sep 15, 2017 MForm 4 →	Sep 19, 3:17 pm EDT	Henry J FuchsPresident, Worldwide R&D	15,000	$33.80	$507,050	151,422	—	plan?
Jul 6, 2017 GForm 5 →	Feb 14, 2018, 8:16 pm EST	Henry J FuchsPresident, Worldwide R&D	415	—	—	133,561	—	plan?
Jun 23, 2017 SForm 4 →	Jun 27, 8:46 pm EDT	George Eric DavisEVP, General Counsel	9,844	$96.60	$950,930	83,581	−10.5%	plan?
Jun 23, 2017 MForm 4 →	Jun 27, 8:46 pm EDT	George Eric DavisEVP, General Counsel	9,844	$38.59	$379,880	93,425	—	plan?
Jun 22, 2017 SForm 4 →	Jun 23, 5:39 pm EDT	Brian MuellerSVP, Corporate Controller	2,671	$100.00	$267,100	12,885	−17.2%	plan?
Jun 22, 2017 MForm 4 →	Jun 23, 5:39 pm EDT	Brian MuellerSVP, Corporate Controller	2,671	$21.51	$57,453	15,556	—	plan?
Jun 16, 2017 SForm 4 →	Jun 20, 6:33 pm EDT	Henry J FuchsPresident, Worldwide R&D	15,000	$90.00	$1,350,000	136,422	−9.91%	plan?
Jun 16, 2017 MForm 4 →	Jun 20, 6:33 pm EDT	Henry J FuchsPresident, Worldwide R&D	15,000	$33.80	$507,050	137,025	—	plan?
Jun 16, 2017 SForm 4 →	Jun 20, 6:31 pm EDT	V Bryan LawlisDirector	3,750	$90.00	$337,500	15,910	−19.1%	plan?
Jun 16, 2017 MForm 4 →	Jun 20, 6:31 pm EDT	V Bryan LawlisDirector	3,750	$38.59	$144,713	19,660	—	plan?
Jun 9, 2017 MForm 4 →	Jun 13, 8:56 pm EDT	George Eric DavisEVP, General Counsel	9,239	$23.54	$217,530	83,581	—	plan?
Jun 7, 2017 SForm 4 →	Jun 9, 6:31 pm EDT	Jeffrey Robert AjerEVP, Chief Commercial Officer	1,004	$89.61	$89,968	47,944	−2.05%	plan?
Jun 6, 2017 AForm 4 →	Jun 8, 6:32 pm EDT	V Bryan LawlisDirector	2,050	—	—	15,910	—	plan?
Jun 6, 2017 AForm 4 →	Jun 8, 6:31 pm EDT	David E I PyottDirector	2,050	—	—	4,910	—	plan?
Jun 6, 2017 AForm 4 →	Jun 8, 6:29 pm EDT	Dennis SlamonDirector	2,050	—	—	9,885	—	plan?
Jun 6, 2017 AForm 4 →	Jun 8, 6:27 pm EDT	Alan LewisDirector	2,050	—	—	26,060	—	plan?
Jun 6, 2017 AForm 4 →	Jun 8, 6:25 pm EDT	Michael G GreyDirector	2,050	—	—	29,810	—	plan?
Jun 6, 2017 AForm 4 →	Jun 8, 6:23 pm EDT	Elaine J HeronDirector	2,050	—	—	39,185	—	plan?
Jun 6, 2017 AForm 4 →	Jun 8, 6:21 pm EDT	Richard A MeierDirector	2,050	—	—	36,310	—	plan?
Jun 6, 2017 AForm 4 →	Jun 8, 6:18 pm EDT	Willard H DereDirector	2,050	—	—	4,690	—	plan?
Jun 5, 2017 SForm 4 →	Jun 7, 8:26 pm EDT	George Eric DavisEVP, General Counsel	9,471	$91.04	$862,230	74,342	−11.3%	plan?
Jun 2, 2017 FForm 4 →	Jun 6, 9:07 pm EDT	Daniel K SpiegelmanEVP, Chief Financial Officer	1,801	$90.72	$163,387	23,303	—	plan?
Jun 2, 2017 FForm 4 →	Jun 6, 9:02 pm EDT	Brian MuellerSVP, Corporate Controller	376	$90.72	$34,111	12,885	—	plan?
Jun 2, 2017 FForm 4 →	Jun 6, 8:57 pm EDT	Henry J FuchsPresident, Worldwide R&D	2,036	$90.72	$184,706	136,422	—	plan?
Jun 2, 2017 FForm 4 →	Jun 6, 8:50 pm EDT	Jeffrey Robert AjerEVP, Chief Commercial Officer	1,488	$90.72	$134,991	48,948	—	plan?
Jun 2, 2017 FForm 4 →	Jun 6, 8:45 pm EDT	Robert BaffiEVP, Technical Operations	1,644	$90.72	$149,144	144,583	—	plan?
Jun 2, 2017 FForm 4 →	Jun 6, 8:39 pm EDT	George Eric DavisEVP, General Counsel	1,488	$90.72	$134,991	83,813	—	plan?
Jun 2, 2017 SForm 4 →	Jun 6, 8:34 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	10,000	$90.13	$901,300	226,924	−4.22%	plan?
Jun 2, 2017 FMForm 4 →	Jun 6, 8:34 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	16,640	$46.62	$775,681	231,924	—	plan?
Jun 1, 2017 SForm 4 →	Jun 5, 7:05 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	5,000	$87.53	$437,650	233,564	−2.10%	plan?
Jun 1, 2017 MForm 4 →	Jun 5, 7:05 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	5,000	$17.33	$86,650	238,564	—	plan?
May 31, 2017 SForm 4 →	Jun 2, 5:52 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	7,423	$88.29	$655,377	233,564	−3.08%	plan?
May 31, 2017 MForm 4 →	Jun 2, 5:52 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	7,423	$17.33	$128,641	240,987	—	plan?
May 24, 2017 SForm 4 →	May 26, 5:02 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	5,000	$88.38	$441,900	233,564	−2.10%	plan?
May 24, 2017 MForm 4 →	May 26, 5:02 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	5,000	$17.33	$86,650	238,564	—	plan?
May 17, 2017 SForm 4 →	May 19, 10:33 am EDT	Jean Jacques BienaimeChief Executive Officer, Director	5,000	$91.73	$458,650	233,564	−2.10%	plan?
May 17, 2017 MForm 4 →	May 19, 10:33 am EDT	Jean Jacques BienaimeChief Executive Officer, Director	5,000	$17.33	$86,650	238,564	—	plan?
May 15, 2017 FMForm 4 →	May 17, 6:55 pm EDT	George Eric DavisEVP, General Counsel	2,242	$52.09	$116,775	85,301	—	plan?
May 15, 2017 FForm 4 →	May 17, 6:53 pm EDT	Brian MuellerSVP, Corporate Controller	207	$91.50	$18,941	13,261	—	plan?
May 15, 2017 FForm 4 →	May 17, 6:51 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	4,932	$91.50	$451,278	233,564	—	plan?
May 15, 2017 FForm 4 →	May 17, 6:42 pm EDT	Jeffrey Robert AjerEVP, Chief Commercial Officer	1,096	$91.50	$100,284	50,436	—	plan?
May 12, 2017 SForm 4 →	May 16, 6:47 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	5,000	$89.23	$446,150	238,496	−2.05%	plan?
May 12, 2017 MForm 4 →	May 16, 6:47 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	5,000	$17.33	$86,650	243,496	—	plan?
May 8, 2017 SForm 4 →	May 10, 3:23 pm EDT	Brian MuellerSVP, Corporate Controller	7,482	$91.87	$687,334	13,468	−35.7%	plan?
May 5, 2017 MForm 4 →	May 9, 1:24 pm EDT	Richard A MeierDirector	7,500	$17.33	$129,975	34,260	—	plan?
May 5, 2017 SForm 4 →	May 9, 1:23 pm EDT	Jeffrey Robert AjerEVP, Chief Commercial Officer	4,486	$99.00	$444,114	51,532	−8.01%	plan?
May 5, 2017 MForm 4 →	May 9, 1:23 pm EDT	Jeffrey Robert AjerEVP, Chief Commercial Officer	4,486	$36.31	$162,879	55,030	—	plan?
May 5, 2017 SForm 4 →	May 9, 1:21 pm EDT	George Eric DavisEVP, General Counsel	2,500	$100.34	$250,852	85,251	−2.85%	plan?
May 5, 2017 SForm 4 →	May 9, 1:19 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	10,000	$96.09	$960,850	238,496	−4.02%	plan?
May 2, 2017 SForm 4 →	May 4, 8:54 pm EDT	Jeffrey Robert AjerEVP, Chief Commercial Officer	302	$96.74	$29,215	51,532	−0.58%	plan?
Apr 28, 2017 AFForm 4 →	May 17, 6:50 pm EDT	Daniel K SpiegelmanEVP, Chief Financial Officer	1,877	$89.75	$168,460	25,104	—	plan? late
Apr 28, 2017 AFForm 4 →	May 17, 6:48 pm EDT	Henry J FuchsPresident, Worldwide R&D	2,338	$88.76	$207,526	138,458	—	plan? late
Apr 28, 2017 AFForm 4 →	May 17, 6:46 pm EDT	Robert BaffiEVP, Technical Operations	1,868	$88.07	$164,521	146,227	—	plan? late
Apr 28, 2017 AMForm 4 →	May 10, 3:23 pm EDT	Brian MuellerSVP, Corporate Controller	2,870	$26.10	$74,908	16,068	—	plan? late
Apr 28, 2017 AMForm 4 →	May 9, 1:21 pm EDT	George Eric DavisEVP, General Counsel	2,802	$42.01	$117,707	87,751	—	plan? late
Apr 28, 2017 AMForm 4 →	May 9, 1:19 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	10,302	$18.88	$194,532	243,496	—	plan? late
Apr 28, 2017 AForm 4 →	May 4, 8:54 pm EDT	Jeffrey Robert AjerEVP, Chief Commercial Officer	302	$70.30	$21,232	51,834	—	plan? late
Apr 27, 2017 SForm 4 →	May 1, 5:39 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	5,000	$95.72	$478,600	238,194	−2.06%	plan?
Apr 27, 2017 MForm 4 →	May 1, 5:39 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	5,000	$17.33	$86,650	243,194	—	plan?
Apr 25, 2017 SForm 4 →	Apr 27, 6:49 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	5,000	$94.00	$470,000	238,194	−2.06%	plan?
Apr 25, 2017 MForm 4 →	Apr 27, 6:49 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	5,000	$17.33	$86,650	243,194	—	plan?
Apr 4, 2017 MForm 4 →	Apr 6, 5:28 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	3,000	$14.39	$43,170	238,194	—	plan?
Mar 29, 2017 SForm 4 →	Mar 31, 5:34 pm EDT	Jeffrey Robert AjerEVP, Chief Commercial Officer	3,890	$89.15	$346,794	51,532	−7.02%	plan?
Mar 22, 2017 AForm 4 →	Mar 24, 6:48 pm EDT	George Eric DavisEVP, General Counsel	11,220	—	—	84,949	—	plan?
Mar 22, 2017 AForm 4 →	Mar 24, 6:47 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	44,520	—	—	235,194	—	plan?
Mar 22, 2017 AForm 4 →	Mar 24, 6:46 pm EDT	Brian MuellerSVP, Corporate Controller	4,790	—	—	18,080	—	plan?
Mar 22, 2017 AForm 4 →	Mar 24, 6:45 pm EDT	Henry J FuchsPresident, Worldwide R&D	19,790	—	—	140,192	—	plan?
Mar 22, 2017 AForm 4 →	Mar 24, 6:43 pm EDT	Jeffrey Robert AjerEVP, Chief Commercial Officer	12,200	—	—	55,422	—	plan?
Mar 22, 2017 AForm 4 →	Mar 24, 6:41 pm EDT	Daniel K SpiegelmanEVP, Chief Financial Officer	12,200	—	—	26,671	—	plan?
Mar 22, 2017 AForm 4 →	Mar 24, 6:40 pm EDT	Robert BaffiEVP, Technical Operations	11,870	—	—	147,491	—	plan?
Mar 16, 2017 SForm 4 →	Mar 17, 6:31 pm EDT	George Eric DavisEVP, General Counsel	2,238	$91.96	$205,806	73,729	−2.95%	plan?
Mar 16, 2017 SForm 4 →	Mar 17, 6:30 pm EDT	Daniel K SpiegelmanEVP, Chief Financial Officer	1,989	$91.96	$182,908	14,471	−12.1%	plan?
Mar 15, 2017 FForm 4 →	Mar 17, 6:36 pm EDT	Jeffrey Robert AjerEVP, Chief Commercial Officer	3,288	$92.50	$304,140	43,222	—	plan?
Mar 15, 2017 FForm 4 →	Mar 17, 6:35 pm EDT	Henry J FuchsPresident, Worldwide R&D	5,116	$92.50	$473,230	120,402	—	plan?
Mar 15, 2017 FForm 4 →	Mar 17, 6:34 pm EDT	Robert BaffiEVP, Technical Operations	3,289	$92.50	$304,233	135,621	—	plan?
Mar 15, 2017 FForm 4 →	Mar 17, 6:32 pm EDT	Brian MuellerSVP, Corporate Controller	712	$91.69	$65,281	13,290	—	plan?
Mar 15, 2017 FForm 4 →	Mar 17, 6:31 pm EDT	George Eric DavisEVP, General Counsel	2,995	$92.50	$277,038	75,967	—	plan?
Mar 15, 2017 FForm 4 →	Mar 17, 6:30 pm EDT	Daniel K SpiegelmanEVP, Chief Financial Officer	4,301	$92.50	$397,843	16,460	—	plan?
Mar 15, 2017 SForm 4 →	Mar 17, 6:27 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	10,000	$91.69	$916,900	190,674	−4.98%	plan?
Mar 15, 2017 FMForm 4 →	Mar 17, 6:27 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	25,690	$73.75	$1,894,625	195,674	—	plan?
Mar 13, 2017 SForm 4 →	Mar 15, 7:16 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	5,000	$92.68	$463,400	206,364	−2.37%	plan?
Mar 13, 2017 MForm 4 →	Mar 15, 7:16 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	5,000	$17.33	$86,650	211,364	—	plan?
Mar 9, 2017 SForm 4 →	Mar 13, 7:59 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	11,000	$90.59	$996,530	206,364	−5.06%	plan?
Mar 9, 2017 MForm 4 →	Mar 13, 7:59 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	11,000	$17.33	$190,630	211,364	—	plan?
Mar 7, 2017 SForm 4 →	Mar 8, 7:31 pm EST	Jeffrey Robert AjerEVP, Chief Commercial Officer	5,000	$90.56	$452,800	46,510	−9.71%	plan?
Mar 6, 2017 SForm 4 →	Mar 8, 7:28 pm EST	Daniel K SpiegelmanEVP, Chief Financial Officer	2,303	$93.32	$214,916	20,761	−9.99%	plan?

Reported at this company — derivatives (options, RSUs, warrants)

Trade	Reported (ET)	Insider	Shares	Avg price	Total	Owned after	Δ stake	Flags
Mar 22, 2017 AForm 4 →	Mar 24, 6:43 pm EDT	Jeffrey Robert AjerEVP, Chief Commercial Officer	39,480	—	—	39,480	—
Mar 22, 2017 AForm 4 →	Mar 24, 6:41 pm EDT	Daniel K SpiegelmanEVP, Chief Financial Officer	39,480	—	—	39,480	—
Mar 22, 2017 AForm 4 →	Mar 24, 6:40 pm EDT	Robert BaffiEVP, Technical Operations	38,420	—	—	38,420	—
Mar 15, 2017 MForm 4 →	Mar 17, 6:27 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	10,000	—	—	57,423	—
Mar 13, 2017 MForm 4 →	Mar 15, 7:16 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	5,000	—	—	67,423	—
Mar 9, 2017 MForm 4 →	Mar 13, 7:59 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	11,000	—	—	72,423	—
Mar 1, 2017 MForm 4 →	Mar 2, 6:14 pm EST	V Bryan LawlisDirector	7,500	—	—	0	—
Feb 28, 2017 MForm 4 →	Mar 2, 6:20 pm EST	Daniel K SpiegelmanEVP, Chief Financial Officer	30,000	—	—	21,700	—
Feb 24, 2017 MForm 4 →	Feb 28, 4:37 pm EST	Henry J FuchsPresident, Worldwide R&D	15,000	—	—	20,225	—
Jan 25, 2017 MForm 4 →	Jan 27, 5:46 pm EST	Jean Jacques BienaimeChief Executive Officer, Director	10,000	—	—	83,423	—
Jan 10, 2017 MForm 4 →	Jan 12, 6:48 pm EST	Jean Jacques BienaimeChief Executive Officer, Director	8,000	—	—	93,423	—
Jan 6, 2017 MForm 4 →	Jan 10, 4:53 pm EST	Jean Jacques BienaimeChief Executive Officer, Director	8,000	—	—	101,423	—
Dec 29, 2016 MForm 4 →	Jan 3, 2017, 5:46 pm EST	Jean Jacques BienaimeChief Executive Officer, Director	8,000	—	—	109,423	—
Nov 25, 2016 MForm 4 →	Nov 29, 8:34 pm EST	Henry J FuchsPresident, Worldwide R&D	15,000	—	—	35,225	—
Nov 21, 2016 MForm 4 →	Nov 23, 4:42 pm EST	Jean Jacques BienaimeChief Executive Officer, Director	139,487	—	—	140,513	—
Nov 18, 2016 MForm 4 →	Nov 22, 7:13 pm EST	George Eric DavisEVP, General Counsel	5,000	$38.59	$192,950	42,344	—
Nov 16, 2016 MForm 4 →	Nov 18, 5:37 pm EST	Jean Jacques BienaimeChief Executive Officer, Director	41,670	—	—	0	—
Nov 9, 2016 MForm 4 →	Nov 14, 1:59 pm EST	V Bryan LawlisDirector	7,500	—	—	7,500	—	late
Nov 7, 2016 MForm 4 →	Nov 9, 8:23 pm EST	Jean Jacques BienaimeChief Executive Officer, Director	140,000	—	—	140,000	—
Oct 27, 2016 MForm 4 →	Oct 31, 7:33 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	120,000	—	—	117,000	—
Oct 17, 2016 MForm 4 →	Oct 19, 4:41 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	41,666	—	—	41,670	—
Oct 13, 2016 MForm 4 →	Oct 17, 7:16 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	64,125	—	—	11,000	—
Sep 30, 2016 MForm 4 →	Oct 4, 3:59 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	53,125	—	—	265,625	—
Sep 29, 2016 MForm 4 →	Oct 3, 6:37 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	53,125	—	—	318,750	—
Sep 15, 2016 MForm 4 →	Sep 19, 6:41 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	137,368	—	—	83,336	—
Aug 26, 2016 MForm 4 →	Aug 30, 9:07 pm EDT	Henry J FuchsEVP, Chief Medical Officer	15,000	—	—	50,225	—
Aug 16, 2016 MForm 4 →	Aug 17, 4:37 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	41,666	—	—	125,002	—
Jul 27, 2016 MForm 4 →	Jul 28, 7:02 pm EDT	V Bryan LawlisDirector	1,100	—	—	15,000	—
Jul 22, 2016 MForm 4 →	Jul 26, 6:57 pm EDT	V Bryan LawlisDirector	6,400	—	—	16,100	—
Jul 18, 2016 MForm 4 →	Jul 20, 7:51 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	41,666	—	—	166,668	—
Jul 15, 2016 AForm 4/A →	Sep 1, 6:24 pm EDT	Kathryn E FalbergDirector	9,880	—	—	9,880	—
Jul 15, 2016 AForm 4/A →	Sep 1, 6:23 pm EDT	Willard H DereDirector	9,880	—	—	9,880	—
Jul 15, 2016 AForm 4 →	Jul 19, 5:22 pm EDT	Kathryn E FalbergDirector	8,230	—	—	8,230	—	amended
Jul 15, 2016 AForm 4 →	Jul 19, 5:20 pm EDT	Willard H DereDirector	8,230	—	—	8,230	—	amended
Jul 14, 2016 MForm 4 →	Jul 18, 6:02 pm EDT	George Eric DavisEVP, General Counsel	2,656	$38.59	$102,495	4,823	—
Jun 16, 2016 MForm 4 →	Jun 20, 8:23 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	41,666	—	—	208,334	—
Jun 6, 2016 AForm 4 →	Jun 8, 8:08 pm EDT	Dennis SlamonDirector	4,440	—	—	4,440	—
Jun 6, 2016 AForm 4 →	Jun 8, 8:07 pm EDT	David E I PyottDirector	2,220	—	—	2,220	—
Jun 6, 2016 AForm 4 →	Jun 8, 8:06 pm EDT	Richard A MeierDirector	4,440	—	—	4,440	—
Jun 6, 2016 AForm 4 →	Jun 8, 8:04 pm EDT	Alan LewisDirector	4,440	—	—	4,400	—
Jun 6, 2016 AForm 4 →	Jun 8, 8:02 pm EDT	V Bryan LawlisDirector	4,440	—	—	4,440	—	amended
Jun 6, 2016 AForm 4 →	Jun 8, 7:57 pm EDT	Elaine J HeronDirector	4,440	—	—	0	—
Jun 6, 2016 AForm 4 →	Jun 8, 7:55 pm EDT	Michael G GreyDirector	4,440	—	—	4,440	—
May 31, 2016 MForm 4/A →	Jun 8, 8:11 pm EDT	Daniel K SpiegelmanEVP, Chief Financial Officer	16,896	—	—	2,604	—
May 31, 2016 MForm 4 →	Jun 2, 6:21 pm EDT	Daniel K SpiegelmanEVP, Chief Financial Officer	16,896	—	—	2,604	—	amended
May 26, 2016 MForm 4 →	May 31, 6:52 pm EDT	Henry J FuchsEVP, Chief Medical Officer	15,000	—	—	65,225	—
May 5, 2016 MForm 4 →	May 9, 8:47 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	60,000	—	—	0	—
May 2, 2016 MForm 4 →	May 4, 10:11 am EDT	Jean Jacques BienaimeChief Executive Officer, Director	36,500	—	—	0	—
Apr 5, 2016 MForm 4 →	Apr 7, 8:49 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	3,000	—	—	237,000	—
Mar 15, 2016 AForm 4 →	Mar 17, 5:29 pm EDT	George Eric DavisEVP, General Counsel	34,270	—	—	34,270	—
Mar 15, 2016 AForm 4 →	Mar 17, 5:27 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	136,050	—	—	136,050	—
Mar 15, 2016 AForm 4 →	Mar 17, 5:26 pm EDT	Daniel K SpiegelmanEVP, Chief Financial Officer	37,290	—	—	37,290	—
Mar 15, 2016 AForm 4 →	Mar 17, 5:25 pm EDT	Robert BaffiEVP, Technical Operations	36,280	—	—	36,280	—	amended
Mar 15, 2016 AForm 4 →	Mar 17, 5:22 pm EDT	Henry J FuchsEVP, Chief Medical Officer	44,340	—	—	44,340	—
Mar 15, 2016 AForm 4 →	Mar 17, 5:20 pm EDT	Brian MuellerVP, Corporate Controller	7,000	—	—	7,000	—
Mar 15, 2016 AForm 4 →	Mar 17, 5:18 pm EDT	Jeffrey Robert AjerEVP, Chief Commercial Officer	36,280	—	—	36,280	—
Feb 22, 2016 MForm 4 →	Feb 23, 4:41 pm EST	Michael G GreyDirector	7,500	—	—	0	—
Jan 4, 2016 AForm 4 →	Jan 6, 4:07 pm EST	David E I PyottDirector	6,100	—	—	6,100	—
Nov 16, 2015 MForm 4 →	Nov 18, 5:10 pm EST	V Bryan LawlisDirector	7,500	—	—	22,500	—
Nov 16, 2015 MForm 4 →	Nov 18, 4:49 pm EST	Michael G GreyDirector	7,500	—	—	7,500	—
Nov 16, 2015 MForm 4 →	Nov 18, 4:03 pm EST	Daniel K SpiegelmanEVP, Chief Financial Officer	20,000	—	—	19,500	—
Sep 8, 2015 MForm 4 →	Sep 25, 12:42 pm EDT	Elaine J HeronDirector	15,000	—	—	0	—	late
Jul 20, 2015 MForm 4 →	Jul 22, 3:21 pm EDT	Jeffrey Robert AjerSVP, Chief Commercial Of	3,000	—	—	39,700	—
Jun 10, 2015 AForm 4 →	Jun 18, 4:35 pm EDT	William D YoungDirector	3,300	—	—	3,300	—	late
Jun 10, 2015 AForm 4 →	Jun 18, 4:33 pm EDT	Dennis SlamonDirector	3,300	—	—	3,300	—	late
Jun 10, 2015 AForm 4 →	Jun 18, 4:31 pm EDT	Richard A MeierDirector	3,300	—	—	3,300	—	late
Jun 10, 2015 AForm 4 →	Jun 18, 4:28 pm EDT	Alan LewisDirector	3,300	—	—	3,300	—	late
Jun 10, 2015 AForm 4 →	Jun 18, 4:26 pm EDT	V Bryan LawlisDirector	3,300	—	—	3,300	—	late
Jun 10, 2015 AForm 4 →	Jun 18, 4:24 pm EDT	Pierre LapalmeDirector	3,300	—	—	3,300	—	late
Jun 10, 2015 AForm 4 →	Jun 18, 4:22 pm EDT	Elaine J HeronDirector	3,300	—	—	3,300	—	late
Jun 10, 2015 AForm 4 →	Jun 18, 4:19 pm EDT	Michael G GreyDirector	3,300	—	—	3,300	—	late
Jun 10, 2015 AForm 4 →	Jun 18, 4:13 pm EDT	Kenneth BateDirector	3,300	—	—	3,300	—	late
May 27, 2015 MForm 4/A →	Oct 13, 2017, 8:43 pm EDT	Daniel K SpiegelmanEVP, Chief Financial Officer	34,078	—	—	35,552	—
May 6, 2015 MForm 4 →	May 8, 5:49 pm EDT	Jeffrey Robert AjerSVP, Chief Commercial Of	33,631	—	—	2,166	—
Apr 1, 2015 MForm 4 →	May 5, 7:02 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	23,218	—	—	0	—	late
Apr 1, 2015 MForm 4 →	Apr 3, 1:05 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	22,546	—	—	23,218	—
Mar 16, 2015 MForm 4 →	Mar 18, 7:50 pm EDT	Henry J FuchsEVP, Chief Medical Officer	40,000	—	—	2,000	—
Mar 16, 2015 AForm 4 →	Mar 17, 7:37 pm EDT	Brian MuellerVP, Corporate Controller	9,000	—	—	9,000	—
Mar 13, 2015 MForm 4 →	Mar 17, 6:03 pm EDT	George Eric DavisSVP, General Counsel	15,000	—	—	15,347	—
Mar 9, 2015 MForm 4 →	Mar 11, 6:32 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	15,000	—	—	46,500	—
Mar 3, 2015 AMForm 4 →	Mar 5, 8:20 pm EST	Jean Jacques BienaimeChief Executive Officer, Director	100,500	—	—	51,500	—
Mar 3, 2015 AForm 4 →	Mar 5, 8:11 pm EST	George Eric DavisSVP, General Counsel	21,900	—	—	21,900	—
Mar 3, 2015 AForm 4 →	Mar 5, 8:05 pm EST	Jeffrey Robert AjerSVP, Chief Commercial Of	23,900	—	—	23,900	—
Mar 3, 2015 AForm 4 →	Mar 5, 8:04 pm EST	Henry J FuchsEVP, Chief Medical Officer	30,500	—	—	30,500	—	amended
Mar 3, 2015 AMForm 4 →	Mar 5, 8:00 pm EST	Robert BaffiEVP, Technical Operations	37,951	—	—	0	—
Mar 3, 2015 AForm 4 →	Mar 5, 7:54 pm EST	Daniel K SpiegelmanEVP, Chief Financial Officer	23,900	—	—	23,900	—
Mar 3, 2015 MForm 4 →	Mar 5, 5:34 pm EST	Pierre LapalmeDirector	20,000	—	—	12,500	—
Mar 2, 2015 MForm 4 →	Mar 4, 7:48 pm EST	Daniel K SpiegelmanEVP, Chief Financial Officer	15,500	—	—	39,500	—
Mar 2, 2015 MForm 4 →	Mar 4, 7:41 pm EST	George Eric DavisSVP, General Counsel	20,000	$26.49	$529,800	3,225	—
Mar 2, 2015 MForm 4 →	Mar 4, 7:39 pm EST	Jean Jacques BienaimeChief Executive Officer, Director	3,000	—	—	61,500	—
Dec 2, 2014 MForm 4 →	Mar 5, 2015, 5:31 pm EST	Brian MuellerVP, Corporate Controller	7,000	—	—	7,491	—	late
Jun 4, 2014 AForm 4 →	Mar 5, 2015, 5:28 pm EST	Brian MuellerVP, Corporate Controller	10,000	—	—	10,000	—	late
May 22, 2010 MForm 4 →	Jun 8, 2015, 5:52 pm EDT	Jean Jacques BienaimeChief Executive Officer, Director	12,500	—	—	20,000	—	late