Form4insider filings, from the source

Insider holders · CIK 0001714899

Denali Therapeutics Inc. · DNLI

Every insider with a reported Table I holding at this company, ranked by their last-reported share count. A balance is only as fresh as its filing — the report date sits next to every row on purpose. ← Back to activity

InsiderDirect sharesIndirect sharesTotal reportedLast report (ET)From
Neuro Line Partners LP10% Owner—19,462,49919,462,499Dec 14, 2017 · 4:09 pm ESTForm 4
Bratton Capital Management, L.P.10% Owner—19,462,49919,462,499Dec 14, 2017 · 4:09 pm ESTForm 4
Bratton Capital Inc.10% Owner—19,462,49919,462,499Dec 14, 2017 · 4:09 pm ESTForm 4
AKDL, L.P.10% Owner—19,462,49919,462,499Dec 14, 2017 · 4:09 pm ESTForm 4
Crestline SI (GP), L.P.10% Owner—19,462,49919,462,499Dec 14, 2017 · 4:09 pm ESTForm 4
Crestline Investors, Inc.10% Owner—19,462,49919,462,499Dec 14, 2017 · 4:09 pm ESTForm 4
Crestline Management, LP10% Owner—19,462,49919,462,499Dec 14, 2017 · 4:09 pm ESTForm 4
Douglas K Bratton10% Owner—19,462,49919,462,499Dec 14, 2017 · 4:09 pm ESTForm 4
ARCH Venture Partners VIII, L.P.10% Owner11,068,749—11,068,749Dec 12, 2017 · 5:46 pm ESTForm 4
ARCH Venture Partners VIII, LLC10% Owner11,068,749—11,068,749Dec 12, 2017 · 5:46 pm ESTForm 4
ARCH Venture Fund VIII, L.P.10% Owner11,068,749—11,068,749Dec 12, 2017 · 5:46 pm ESTForm 4
Clinton Bybee10% Owner11,068,749—11,068,749Dec 12, 2017 · 5:46 pm ESTForm 4
Robert NelsenDirector—11,068,74911,068,749Dec 12, 2017 · 5:40 pm ESTForm 4
Keith Crandell10% Owner11,068,749—11,068,749Dec 12, 2017 · 5:46 pm ESTForm 4
Flagship Ventures Fund V General Partner LLC10% Owner8,918,749—8,918,749Dec 12, 2017 · 5:52 pm ESTForm 4
Flagship Ventures Fund V, L.P.10% Owner8,918,749—8,918,749Dec 12, 2017 · 5:52 pm ESTForm 4
Noubar Afeyan10% Owner8,918,749—8,918,749Dec 12, 2017 · 5:52 pm ESTForm 4
Baker Bros. Advisors (GP) LLCDirector—3,422,3663,422,366Jun 5, 2026 · 4:28 pm EDTForm 4
667, L.P.Director—3,422,3663,422,366Jun 5, 2026 · 4:28 pm EDTForm 4
Baker Brothers Life Sciences LPDirector—3,422,3663,422,366Jun 5, 2026 · 4:28 pm EDTForm 4
BAKER BROS. ADVISORS LPDirector—3,422,3663,422,366Jun 5, 2026 · 4:28 pm EDTForm 4
Felix BakerDirector—3,422,3663,422,366Jun 5, 2026 · 4:28 pm EDTForm 4
Julian BakerDirector—3,422,3663,422,366Jun 5, 2026 · 4:28 pm EDTForm 4
Marc Tessier-LavigneDirector3,139,043—3,139,043Dec 12, 2017 · 5:45 pm ESTForm 4
Ryan J. WattsPresident and CEO296,8332,120,3842,417,217Aug 14, 2026 · 4:48 pm EDTForm 4
FIL Ltdrelationship not stated1,914,8331,3791,916,212Dec 14, 2017 · 3:20 pm ESTForm 4
Steve E. KrognesDirector38,202781,797819,999Jun 5, 2026 · 4:45 pm EDTForm 4
Alexander O. SchuthCOFO and Secretary278,995523,749802,744Sep 3, 2026 · 4:17 pm EDTForm 4
FMR LLC10% Owner—750,001750,001Dec 22, 2017 · 10:25 am ESTForm 3
Jay T FlatleyDirector22,628336,313358,941Jun 5, 2026 · 4:46 pm EDTForm 4
Peter Scott ChinChief Medical Officer204,538—204,538Sep 9, 2026 · 4:44 pm EDTForm 4
Carole HoChief Medical Officer46,875142,615189,490Mar 5, 2019 · 6:21 pm ESTForm 4
Vicki L SatoDirector137,500—137,500Dec 12, 2017 · 5:42 pm ESTForm 4
David P SchenkeinDirector21,66531,23252,897Jun 5, 2026 · 4:45 pm EDTForm 4
Peter S KleinDirector33,941—33,941Jun 5, 2026 · 4:45 pm EDTForm 4
Jennifer E. CookDirector32,483—32,483Jun 5, 2026 · 4:43 pm EDTForm 4
Nancy ThornberryDirector19,686—19,686Sep 4, 2026 · 5:02 pm EDTForm 4
Timothy Van HauwermeirenDirector17,040—17,040Jun 5, 2026 · 4:44 pm EDTForm 4
Douglas G. ColeDirector0—0Dec 7, 2017 · 6:14 pm ESTForm 3

Balances come from each insider’s most recent filing that reports a Table I holding; an insider who left the company years ago still appears with their last-known figure and its date. Indirect totals collapse multiple vehicles (trusts, LLCs) into one number — open the filing for the breakdown. Shares as filed, not split-adjusted.