Company · CIK 0000875320 · SIC 2834 — Pharmaceutical Preparations · Nasdaq

VERTEX PHARMACEUTICALS INC / MA · VRTX

Insider activity reported against this company. All insider holders · Files at: CRSP. On EDGAR ↗

Period1M 3M 6M 1Y 2Y All datashares as filed — not split-adjusted

Open-market activity at this companybuys $2,878 · 1sales $662.8M · 396net −$662.8M

Reported at this company — common stock

Trade	Reported (ET)	Insider	Shares	Avg price	Total	Owned after	Δ stake	Flags
Sep 9, 2015 SForm 4 →	Sep 18, 8:05 am EDT	Joshua S BogerDirector	10,400	$133.24	$1,385,713	345,284	−2.92%	plan? late
Sep 9, 2015 SForm 4 →	Sep 11, 9:10 am EDT	Joshua S BogerDirector	10,400	$131.41	$1,366,626	345,284	−2.92%	plan?
Sep 9, 2015 MForm 4 →	Sep 11, 9:10 am EDT	Joshua S BogerDirector	10,400	$35.64	$370,656	355,684	—	plan?
Sep 4, 2015 SForm 4 →	Sep 9, 4:28 pm EDT	Stuart A ArbuckleEVP\Chief Commercial Officer	9,063	$125.77	$1,139,818	127,515	−6.64%	plan?
Sep 4, 2015 MForm 4 →	Sep 9, 4:28 pm EDT	Stuart A ArbuckleEVP\Chief Commercial Officer	9,063	$53.74	$487,046	136,578	—	plan?
Sep 2, 2015 SForm 4 →	Sep 3, 5:25 pm EDT	Joshua S BogerDirector	10,400	$125.85	$1,308,870	345,284	−2.92%	plan?
Sep 2, 2015 MForm 4 →	Sep 3, 5:25 pm EDT	Joshua S BogerDirector	10,400	$35.64	$370,656	355,684	—	plan?
Sep 1, 2015 SForm 4 →	Sep 3, 5:24 pm EDT	Yuchun LeeDirector	1,125	$125.40	$141,070	208	−84.4%	plan?
Sep 1, 2015 MForm 4 →	Sep 3, 5:24 pm EDT	Yuchun LeeDirector	1,333	$57.27	$76,341	1,333	—	plan?
Aug 26, 2015 SForm 4 →	Aug 27, 3:46 pm EDT	Joshua S BogerDirector	10,400	$124.71	$1,297,030	345,284	−2.92%	plan?
Aug 26, 2015 MForm 4 →	Aug 27, 3:46 pm EDT	Joshua S BogerDirector	10,400	$35.64	$370,656	355,684	—	plan?
Aug 19, 2015 SForm 4 →	Aug 20, 6:02 pm EDT	Joshua S BogerDirector	10,400	$139.93	$1,455,309	345,284	−2.92%	plan?
Aug 19, 2015 MForm 4 →	Aug 20, 6:02 pm EDT	Joshua S BogerDirector	10,400	$35.64	$370,656	355,684	—	plan?
Aug 12, 2015 SForm 4 →	Aug 14, 2:33 pm EDT	Joshua S BogerDirector	10,400	$135.83	$1,412,588	345,284	−2.92%	plan?
Aug 12, 2015 MForm 4 →	Aug 14, 2:33 pm EDT	Joshua S BogerDirector	10,400	$35.64	$370,656	355,684	—	plan?
Aug 5, 2015 SForm 4 →	Aug 7, 4:23 pm EDT	Joshua S BogerDirector	10,400	$141.26	$1,469,091	345,284	−2.92%	plan?
Aug 5, 2015 MForm 4 →	Aug 7, 4:23 pm EDT	Joshua S BogerDirector	10,400	$35.64	$370,656	355,684	—	plan?
Aug 5, 2015 SForm 4 →	Aug 7, 4:23 pm EDT	Stuart A ArbuckleEVP\Chief Commercial Officer	19,828	$141.28	$2,801,202	127,515	−13.5%	plan?
Aug 5, 2015 MForm 4 →	Aug 7, 4:23 pm EDT	Stuart A ArbuckleEVP\Chief Commercial Officer	19,828	$58.91	$1,168,141	147,343	—	plan?
Aug 4, 2015 SForm 4 →	Aug 5, 4:18 pm EDT	Bruce I SachsDirector	10,000	$140.13	$1,401,300	21,210	−32.0%	plan?
Aug 4, 2015 MForm 4 →	Aug 5, 4:18 pm EDT	Bruce I SachsDirector	10,000	$34.24	$342,400	31,210	—	plan?
Aug 3, 2015 SForm 4 →	Aug 5, 4:14 pm EDT	Margaret G McGlynnDirector	12,500	$137.28	$1,716,050	1,088	−92.0%	plan?
Aug 3, 2015 MForm 4 →	Aug 5, 4:14 pm EDT	Margaret G McGlynnDirector	12,500	$57.27	$715,875	13,588	—	plan?
Jul 30, 2015 SForm 4 →	Jul 31, 1:44 pm EDT	Paul M SilvaSVP & Corp Controller	860	$128.96	$110,909	18,375	−4.47%	plan?
Jul 30, 2015 MForm 4 →	Jul 31, 1:44 pm EDT	Paul M SilvaSVP & Corp Controller	860	$83.36	$71,690	19,235	—	plan?
Jul 29, 2015 SForm 4 →	Jul 31, 10:30 am EDT	Joshua S BogerDirector	10,400	$126.68	$1,317,440	345,284	−2.92%	plan?
Jul 29, 2015 MForm 4 →	Jul 31, 10:30 am EDT	Joshua S BogerDirector	10,400	$35.64	$370,656	355,684	—	plan?
Jul 27, 2015 SForm 4 →	Jul 29, 4:11 pm EDT	Paul M SilvaSVP & Corp Controller	1,125	$123.28	$138,694	18,375	−5.77%	plan?
Jul 27, 2015 MForm 4 →	Jul 29, 4:11 pm EDT	Paul M SilvaSVP & Corp Controller	1,125	$48.74	$54,833	19,500	—	plan?
Jul 22, 2015 SForm 4 →	Jul 23, 4:28 pm EDT	Joshua S BogerDirector	10,400	$130.92	$1,361,560	345,284	−2.92%	plan?
Jul 22, 2015 MForm 4 →	Jul 23, 4:28 pm EDT	Joshua S BogerDirector	10,400	$35.64	$370,656	355,684	—	plan?
Jul 15, 2015 SForm 4 →	Jul 16, 3:04 pm EDT	Joshua S BogerDirector	12,200	$133.98	$1,634,602	345,284	−3.41%	plan?
Jul 15, 2015 MForm 4 →	Jul 16, 3:04 pm EDT	Joshua S BogerDirector	12,200	$32.91	$401,544	357,484	—	plan?
Jul 13, 2015 SForm 4 →	Jul 15, 6:53 pm EDT	Paul M SilvaSVP & Corp Controller	1,125	$123.79	$139,261	18,375	−5.77%	plan?
Jul 13, 2015 MForm 4 →	Jul 15, 6:53 pm EDT	Paul M SilvaSVP & Corp Controller	1,125	$51.75	$58,219	19,500	—	plan?
Jul 8, 2015 SForm 4 →	Jul 10, 1:58 pm EDT	Joshua S BogerDirector	11,700	$122.74	$1,436,066	345,284	−3.28%	plan?
Jul 8, 2015 MForm 4 →	Jul 10, 1:58 pm EDT	Joshua S BogerDirector	11,700	$33.59	$392,964	356,984	—	plan?
Jul 2, 2015 SForm 4 →	Jul 7, 5:11 pm EDT	Jeffrey ChodakewitzEVP GMDA, CMO	2,291	$129.36	$296,357	100,562	−2.23%	plan?
Jul 2, 2015 MForm 4 →	Jul 7, 5:11 pm EDT	Jeffrey ChodakewitzEVP GMDA, CMO	2,291	$73.51	$168,411	102,853	—	plan?
Jul 1, 2015 SForm 4 →	Jul 2, 2:14 pm EDT	Joshua S BogerDirector	11,700	$125.60	$1,469,498	345,284	−3.28%	plan?
Jul 1, 2015 MForm 4 →	Jul 2, 2:14 pm EDT	Joshua S BogerDirector	11,700	$33.59	$392,964	356,984	—	plan?
Jun 24, 2015 SForm 4 →	Jun 26, 2:58 pm EDT	Joshua S BogerDirector	11,700	$130.41	$1,525,812	345,284	−3.28%	plan?
Jun 24, 2015 MForm 4 →	Jun 26, 2:58 pm EDT	Joshua S BogerDirector	11,700	$33.59	$392,964	356,984	—	plan?
Jun 17, 2015 SForm 4 →	Jun 19, 10:17 am EDT	Joshua S BogerDirector	11,700	$123.90	$1,449,645	345,284	−3.28%	plan?
Jun 17, 2015 MForm 4 →	Jun 19, 10:17 am EDT	Joshua S BogerDirector	11,700	$33.59	$392,964	356,984	—	plan?
Jun 10, 2015 SForm 4 →	Jun 12, 8:29 pm EDT	Joshua S BogerDirector	11,700	$125.02	$1,462,679	345,284	−3.28%	plan?
Jun 10, 2015 MForm 4 →	Jun 12, 8:29 pm EDT	Joshua S BogerDirector	11,700	$33.59	$392,964	356,984	—	plan?
Jun 3, 2015 SForm 4 →	Jun 5, 4:25 pm EDT	Joshua S BogerDirector	11,700	$125.81	$1,471,986	345,284	−3.28%	plan?
Jun 3, 2015 MForm 4 →	Jun 5, 4:25 pm EDT	Joshua S BogerDirector	11,700	$33.59	$392,964	356,984	—	plan?
Jun 1, 2015 SForm 4 →	Jun 3, 4:20 pm EDT	Margaret G McGlynnDirector	12,500	$127.32	$1,591,515	1,088	−92.0%	plan?
Jun 1, 2015 MForm 4 →	Jun 3, 4:20 pm EDT	Margaret G McGlynnDirector	12,500	$55.22	$690,225	13,588	—	plan?
May 27, 2015 SForm 4 →	May 29, 4:03 pm EDT	Joshua S BogerDirector	11,700	$126.08	$1,475,193	345,284	−3.28%	plan?
May 27, 2015 MForm 4 →	May 29, 4:03 pm EDT	Joshua S BogerDirector	11,700	$33.59	$392,964	356,984	—	plan?
May 20, 2015 SForm 4 →	May 21, 4:08 pm EDT	Joshua S BogerDirector	11,700	$126.73	$1,482,774	345,284	−3.28%	plan?
May 19, 2015 MForm 4 →	May 21, 4:16 pm EDT	Terrence C KearneyDirector	1,500	$56.99	$85,485	1,500	—	plan?
May 19, 2015 GMForm 4 →	May 21, 4:08 pm EDT	Joshua S BogerDirector	52,700	$33.59	$392,964	356,984	—	plan?
May 15, 2015 SForm 4 →	May 18, 6:22 pm EDT	Ian F SmithEVP & CFO	378	$125.62	$47,484	118,134	−0.32%	plan?
May 15, 2015 SForm 4 →	May 18, 6:18 pm EDT	Paul M SilvaSVP & Corp Controller	135	$123.85	$16,720	18,375	−0.73%	plan?
May 15, 2015 SForm 4 →	May 18, 6:13 pm EDT	Amit SachdevEVP, Policy, Access & Value	131	$123.85	$16,224	84,901	−0.15%	plan?
May 15, 2015 SForm 4 →	May 18, 6:06 pm EDT	Stuart A ArbuckleEVP\Chief Commercial Officer	148	$123.85	$18,330	127,515	−0.12%	plan?
May 13, 2015 SForm 4 →	May 15, 4:16 pm EDT	Joshua S BogerDirector	11,700	$127.48	$1,491,546	386,284	−2.94%	plan?
May 13, 2015 MForm 4 →	May 15, 4:16 pm EDT	Joshua S BogerDirector	11,700	$33.59	$392,964	397,984	—	plan?
May 6, 2015 SForm 4 →	May 7, 7:37 pm EDT	Joshua S BogerDirector	11,700	$122.79	$1,436,688	386,284	−2.94%	plan?
May 6, 2015 MForm 4 →	May 7, 7:37 pm EDT	Joshua S BogerDirector	11,700	$33.59	$392,964	397,984	—	plan?
May 4, 2015 SForm 4 →	May 6, 4:24 pm EDT	Paul M SilvaSVP & Corp Controller	4,101	$123.68	$507,206	18,375	−18.2%	plan?
May 4, 2015 MForm 4 →	May 6, 4:24 pm EDT	Paul M SilvaSVP & Corp Controller	4,101	$53.24	$218,346	21,351	—	plan?
Apr 30, 2015 SForm 4 →	May 1, 4:47 pm EDT	Paul M SilvaSVP & Corp Controller	859	$124.02	$106,530	18,375	−4.47%	plan?
Apr 30, 2015 MForm 4 →	May 1, 4:47 pm EDT	Paul M SilvaSVP & Corp Controller	859	$83.36	$71,606	19,234	—	plan?
Apr 29, 2015 SForm 4 →	May 1, 5:08 pm EDT	Joshua S BogerDirector	11,700	$124.59	$1,457,726	386,284	−2.94%	plan?
Apr 29, 2015 MForm 4 →	May 1, 5:08 pm EDT	Joshua S BogerDirector	11,700	$33.59	$392,964	397,984	—	plan?
Apr 27, 2015 SForm 4 →	Apr 29, 8:36 pm EDT	Stuart A ArbuckleEVP\Chief Commercial Officer	61,480	$129.36	$7,952,758	127,515	−32.5%	plan?
Apr 27, 2015 GMForm 4 →	Apr 29, 8:36 pm EDT	Stuart A ArbuckleEVP\Chief Commercial Officer	51,025	$58.98	$3,000,404	188,995	—	plan?
Apr 27, 2015 SForm 4 →	Apr 29, 8:34 pm EDT	Terrence C KearneyDirector	68,125	$129.11	$8,795,285	0	−100%	plan?
Apr 27, 2015 MForm 4 →	Apr 29, 8:34 pm EDT	Terrence C KearneyDirector	68,125	$56.82	$3,870,844	68,125	—	plan?
Apr 27, 2015 SForm 4 →	Apr 29, 8:32 pm EDT	Paul M SilvaSVP & Corp Controller	1,125	$129.74	$145,958	18,375	−5.77%	plan?
Apr 27, 2015 MForm 4 →	Apr 29, 8:32 pm EDT	Paul M SilvaSVP & Corp Controller	1,125	$48.74	$54,833	19,500	—	plan?
Apr 22, 2015 SForm 4 →	Apr 24, 4:45 pm EDT	Joshua S BogerDirector	11,700	$132.46	$1,549,724	386,284	−2.94%	plan?
Apr 22, 2015 MForm 4 →	Apr 24, 4:45 pm EDT	Joshua S BogerDirector	11,700	$33.59	$392,964	397,984	—	plan?
Apr 15, 2015 SForm 4 →	Apr 17, 4:44 pm EDT	Joshua S BogerDirector	11,700	$129.25	$1,512,211	386,284	−2.94%	plan?
Apr 15, 2015 MForm 4 →	Apr 17, 4:44 pm EDT	Joshua S BogerDirector	11,700	$33.59	$392,964	397,984	—	plan?
Apr 13, 2015 SForm 4 →	Apr 15, 4:08 pm EDT	Paul M SilvaSVP & Corp Controller	1,125	$128.60	$144,675	18,375	−5.77%	plan?
Apr 13, 2015 MForm 4 →	Apr 15, 4:08 pm EDT	Paul M SilvaSVP & Corp Controller	1,125	$51.75	$58,219	19,500	—	plan?
Apr 8, 2015 SForm 4 →	Apr 10, 4:10 pm EDT	Joshua S BogerDirector	11,700	$123.26	$1,442,148	386,284	−2.94%	plan?
Apr 8, 2015 MForm 4 →	Apr 10, 4:10 pm EDT	Joshua S BogerDirector	11,700	$33.59	$392,964	397,984	—	plan?
Apr 6, 2015 SForm 4 →	Apr 8, 7:25 pm EDT	Margaret G McGlynnDirector	12,500	$118.36	$1,479,523	1,088	−92.0%	plan?
Apr 6, 2015 MForm 4 →	Apr 8, 7:25 pm EDT	Margaret G McGlynnDirector	12,500	$53.85	$673,125	13,588	—	plan?
Apr 2, 2015 SForm 4 →	Apr 6, 4:32 pm EDT	Jeffrey ChodakewitzEVP GMDA, CMO	2,291	$115.50	$264,601	100,562	−2.23%	plan?
Apr 2, 2015 MForm 4 →	Apr 6, 4:32 pm EDT	Jeffrey ChodakewitzEVP GMDA, CMO	2,291	$73.51	$168,411	102,853	—	plan?
Apr 1, 2015 SForm 4 →	Apr 2, 4:25 pm EDT	Joshua S BogerDirector	11,700	$115.87	$1,355,654	386,284	−2.94%	plan?
Apr 1, 2015 MForm 4 →	Apr 2, 4:25 pm EDT	Joshua S BogerDirector	11,700	$33.59	$392,964	397,984	—	plan?
Mar 25, 2015 SForm 4 →	Mar 27, 4:48 pm EDT	Joshua S BogerDirector	11,700	$120.76	$1,412,877	386,284	−2.94%	plan?
Mar 25, 2015 MForm 4 →	Mar 27, 4:48 pm EDT	Joshua S BogerDirector	11,700	$33.59	$392,964	397,984	—	plan?
Mar 23, 2015 SForm 4 →	Mar 24, 6:10 pm EDT	Ian F SmithEVP & CFO	6,042	$125.67	$759,277	118,134	−4.87%	plan?
Mar 23, 2015 SForm 4 →	Mar 24, 6:07 pm EDT	Paul M SilvaSVP & Corp Controller	2,250	$125.65	$282,723	18,375	−10.9%	plan?
Mar 20, 2015 SForm 4 →	Mar 24, 6:04 pm EDT	Bruce I SachsDirector	10,000	$135.52	$1,355,190	21,210	−32.0%	plan?
Mar 20, 2015 MForm 4 →	Mar 24, 6:04 pm EDT	Bruce I SachsDirector	10,000	$29.89	$298,900	31,210	—	plan?
Mar 20, 2015 SForm 4 →	Mar 24, 6:02 pm EDT	Amit SachdevEVP, Policy, Access & Value	17,083	$132.28	$2,259,716	84,901	−16.8%	plan?
Mar 20, 2015 MForm 4 →	Mar 24, 6:02 pm EDT	Amit SachdevEVP, Policy, Access & Value	12,000	$45.55	$546,649	101,984	—	plan?
Mar 20, 2015 SForm 4 →	Mar 24, 5:59 pm EDT	Wayne Joseph RileyDirector	10,000	$135.08	$1,350,800	400	−96.2%	plan?
Mar 20, 2015 MForm 4 →	Mar 24, 5:59 pm EDT	Wayne Joseph RileyDirector	10,000	$59.55	$595,500	10,400	—	plan?

Reported at this company — derivatives (options, RSUs, warrants)

Trade	Reported (ET)	Insider	Shares	Avg price	Total	Owned after	Δ stake	Flags
Aug 5, 2015 MForm 4 →	Aug 7, 4:23 pm EDT	Stuart A ArbuckleEVP\Chief Commercial Officer	19,828	—	—	42,500	—
Aug 4, 2015 MForm 4 →	Aug 5, 4:18 pm EDT	Bruce I SachsDirector	10,000	—	—	10,000	—
Aug 3, 2015 MForm 4 →	Aug 5, 4:14 pm EDT	Margaret G McGlynnDirector	12,500	—	—	12,500	—
Jul 30, 2015 MForm 4 →	Jul 31, 1:44 pm EDT	Paul M SilvaSVP & Corp Controller	860	—	—	6,874	—
Jul 29, 2015 MForm 4 →	Jul 31, 10:30 am EDT	Joshua S BogerDirector	10,400	—	—	271,200	—
Jul 27, 2015 MForm 4 →	Jul 29, 4:11 pm EDT	Paul M SilvaSVP & Corp Controller	1,125	—	—	4,500	—
Jul 22, 2015 MForm 4 →	Jul 23, 4:28 pm EDT	Joshua S BogerDirector	10,400	—	—	281,600	—
Jul 21, 2015 AForm 4 →	Jul 23, 4:36 pm EDT	Ian F SmithEVP & CFO	34,000	—	—	34,000	—
Jul 21, 2015 AForm 4 →	Jul 23, 4:34 pm EDT	Paul M SilvaSVP & Corp Controller	13,750	—	—	13,750	—
Jul 21, 2015 AForm 4 →	Jul 23, 4:33 pm EDT	Amit SachdevEVP, Policy, Access & Value	34,000	—	—	34,000	—
Jul 21, 2015 AForm 4 →	Jul 23, 4:31 pm EDT	Jeffrey M LeidenCEO & President, Director	106,500	—	—	106,500	—
Jul 21, 2015 AForm 4 →	Jul 23, 4:30 pm EDT	Jeffrey ChodakewitzEVP GMDA, CMO	34,000	—	—	34,000	—
Jul 21, 2015 AForm 4 →	Jul 23, 4:27 pm EDT	Stuart A ArbuckleEVP\Chief Commercial Officer	34,000	—	—	34,000	—
Jul 21, 2015 AForm 4 →	Jul 23, 4:25 pm EDT	David AltshulerEVP, Global Research and CSO	34,000	—	—	34,000	—
Jul 15, 2015 MForm 4 →	Jul 16, 3:04 pm EDT	Joshua S BogerDirector	12,200	—	—	292,000	—
Jul 13, 2015 MForm 4 →	Jul 15, 6:53 pm EDT	Paul M SilvaSVP & Corp Controller	1,125	—	—	0	—
Jul 8, 2015 MForm 4 →	Jul 10, 1:58 pm EDT	Joshua S BogerDirector	11,700	—	—	302,400	—
Jul 2, 2015 MForm 4 →	Jul 7, 5:11 pm EDT	Jeffrey ChodakewitzEVP GMDA, CMO	2,291	—	—	41,253	—
Jul 1, 2015 MForm 4 →	Jul 2, 2:14 pm EDT	Joshua S BogerDirector	11,700	—	—	312,800	—
Jun 24, 2015 MForm 4 →	Jun 26, 2:58 pm EDT	Joshua S BogerDirector	11,700	—	—	323,200	—
Jun 17, 2015 MForm 4 →	Jun 19, 10:17 am EDT	Joshua S BogerDirector	11,700	—	—	333,600	—
Jun 10, 2015 MForm 4 →	Jun 12, 8:29 pm EDT	Joshua S BogerDirector	11,700	—	—	344,000	—
Jun 4, 2015 AForm 4 →	Jun 8, 4:05 pm EDT	Sangeeta N. BhatiaDirector	30,000	—	—	30,000	—
Jun 3, 2015 MForm 4 →	Jun 5, 4:25 pm EDT	Joshua S BogerDirector	11,700	—	—	354,400	—
Jun 1, 2015 AForm 4 →	Jun 3, 4:51 pm EDT	William D YoungDirector	20,000	—	—	20,000	—
Jun 1, 2015 AForm 4 →	Jun 3, 4:47 pm EDT	Elaine UllianDirector	22,500	—	—	22,500	—
Jun 1, 2015 AForm 4 →	Jun 3, 4:45 pm EDT	Bruce I SachsDirector	22,500	—	—	22,500	—
Jun 1, 2015 AForm 4 →	Jun 3, 4:43 pm EDT	Wayne Joseph RileyDirector	20,000	—	—	20,000	—
Jun 1, 2015 AForm 4 →	Jun 3, 4:34 pm EDT	Yuchun LeeDirector	20,000	—	—	20,000	—
Jun 1, 2015 AForm 4 →	Jun 3, 4:27 pm EDT	Joshua S BogerDirector	20,000	—	—	20,000	—
Jun 1, 2015 AForm 4 →	Jun 3, 4:24 pm EDT	Terrence C KearneyDirector	20,000	—	—	20,000	—
Jun 1, 2015 AMForm 4 →	Jun 3, 4:20 pm EDT	Margaret G McGlynnDirector	32,500	—	—	0	—
May 27, 2015 MForm 4 →	May 29, 4:03 pm EDT	Joshua S BogerDirector	11,700	—	—	364,800	—
May 20, 2015 MForm 4 →	May 21, 4:08 pm EDT	Joshua S BogerDirector	11,700	—	—	375,200	—
May 19, 2015 MForm 4 →	May 21, 4:16 pm EDT	Terrence C KearneyDirector	1,500	—	—	375	—
May 13, 2015 MForm 4 →	May 15, 4:16 pm EDT	Joshua S BogerDirector	11,700	—	—	385,600	—
May 6, 2015 MForm 4 →	May 7, 7:37 pm EDT	Joshua S BogerDirector	11,700	—	—	396,000	—
May 4, 2015 MForm 4 →	May 6, 4:24 pm EDT	Paul M SilvaSVP & Corp Controller	4,101	—	—	14,179	—
Apr 30, 2015 MForm 4 →	May 1, 4:47 pm EDT	Paul M SilvaSVP & Corp Controller	859	—	—	7,734	—
Apr 29, 2015 MForm 4 →	May 1, 5:08 pm EDT	Joshua S BogerDirector	11,700	—	—	406,400	—
Apr 27, 2015 MForm 4 →	Apr 29, 8:36 pm EDT	Stuart A ArbuckleEVP\Chief Commercial Officer	50,875	—	—	51,000	—
Apr 27, 2015 MForm 4 →	Apr 29, 8:34 pm EDT	Terrence C KearneyDirector	68,125	—	—	0	—
Apr 27, 2015 MForm 4 →	Apr 29, 8:32 pm EDT	Paul M SilvaSVP & Corp Controller	1,125	—	—	5,625	—
Apr 22, 2015 MForm 4 →	Apr 24, 4:45 pm EDT	Joshua S BogerDirector	11,700	—	—	416,800	—
Apr 15, 2015 MForm 4 →	Apr 17, 4:44 pm EDT	Joshua S BogerDirector	11,700	—	—	427,200	—
Apr 13, 2015 MForm 4 →	Apr 15, 4:08 pm EDT	Paul M SilvaSVP & Corp Controller	1,125	—	—	1,125	—
Apr 8, 2015 MForm 4 →	Apr 10, 4:10 pm EDT	Joshua S BogerDirector	11,700	—	—	437,600	—
Apr 6, 2015 AForm 4 →	Apr 8, 7:25 pm EDT	Margaret G McGlynnDirector	12,500	—	—	7,500	—
Apr 2, 2015 MForm 4 →	Apr 6, 4:32 pm EDT	Jeffrey ChodakewitzEVP GMDA, CMO	2,291	—	—	43,544	—
Apr 1, 2015 MForm 4 →	Apr 2, 4:25 pm EDT	Joshua S BogerDirector	11,700	—	—	448,000	—
Mar 25, 2015 MForm 4 →	Mar 27, 4:48 pm EDT	Joshua S BogerDirector	11,700	—	—	458,400	—
Mar 20, 2015 MForm 4 →	Mar 24, 6:04 pm EDT	Bruce I SachsDirector	10,000	—	—	0	—
Mar 20, 2015 MForm 4 →	Mar 24, 6:02 pm EDT	Amit SachdevEVP, Policy, Access & Value	12,000	—	—	28,593	—
Mar 20, 2015 MForm 4 →	Mar 24, 5:59 pm EDT	Wayne Joseph RileyDirector	10,000	—	—	10,000	—
Mar 18, 2015 MForm 4 →	Mar 20, 4:19 pm EDT	Bruce I SachsDirector	10,000	—	—	10,000	—
Mar 18, 2015 MForm 4 →	Mar 20, 4:18 pm EDT	Amit SachdevEVP, Policy, Access & Value	12,000	—	—	39,125	—
Mar 11, 2015 MForm 4 →	Mar 20, 4:17 pm EDT	Joshua S BogerDirector	11,700	—	—	479,200	—	late
Mar 11, 2015 MForm 4 →	Mar 13, 4:30 pm EDT	Joshua S BogerDirector	11,700	—	—	479,200	—
Mar 4, 2015 MForm 4 →	Mar 6, 4:29 pm EST	Joshua S BogerDirector	11,700	—	—	489,600	—
Feb 25, 2015 MForm 4 →	Feb 27, 4:09 pm EST	Joshua S BogerDirector	11,700	—	—	500,000	—
Feb 23, 2015 MForm 4 →	Feb 25, 4:23 pm EST	Paul M SilvaSVP & Corp Controller	2,150	—	—	15,468	—
Feb 18, 2015 MForm 4 →	Feb 20, 4:19 pm EST	Joshua S BogerDirector	11,700	—	—	510,400	—
Feb 11, 2015 MForm 4 →	Feb 13, 4:14 pm EST	Joshua S BogerDirector	5,700	—	—	520,800	—
Feb 5, 2015 MForm 4 →	Feb 6, 5:41 pm EST	Paul M SilvaSVP & Corp Controller	1,688	—	—	13,500	—
Feb 4, 2015 MForm 4 →	Feb 6, 5:43 pm EST	Joshua S BogerDirector	5,700	—	—	525,200	—
Feb 3, 2015 AForm 4 →	Feb 5, 5:18 pm EST	Paul M SilvaSVP & Corp Controller	20,625	—	—	20,625	—
Feb 3, 2015 AForm 4 →	Feb 5, 5:15 pm EST	Amit SachdevEVP, Policy, Access & Value	57,500	—	—	57,500	—
Feb 3, 2015 AForm 4 →	Feb 5, 5:12 pm EST	Jeffrey M LeidenCEO & President, Director	213,000	—	—	213,000	—
Feb 3, 2015 AForm 4 →	Feb 5, 5:09 pm EST	Stuart A ArbuckleEVP\Chief Commercial Officer	68,000	—	—	68,000	—
Feb 3, 2015 AForm 4 →	Feb 5, 5:07 pm EST	Ian F SmithEVP & CFO	68,000	—	—	68,000	—
Feb 3, 2015 AForm 4 →	Feb 5, 5:01 pm EST	Jeffrey ChodakewitzEVP GMDA, CMO	57,500	—	—	57,500	—
Feb 2, 2015 MForm 4 →	Feb 4, 4:53 pm EST	Paul M SilvaSVP & Corp Controller	2,063	—	—	0	—
Jan 28, 2015 MForm 4 →	Jan 30, 4:17 pm EST	Joshua S BogerDirector	10,688	—	—	529,600	—
Jan 26, 2015 MForm 4 →	Jan 28, 5:39 pm EST	Paul M SilvaSVP & Corp Controller	1,125	—	—	6,750	—
Jan 21, 2015 MForm 4 →	Jan 23, 5:12 pm EST	Joshua S BogerDirector	10,500	—	—	534,000	—
Jan 20, 2015 MForm 4 →	Jan 22, 5:24 pm EST	Bruce I SachsDirector	139	—	—	0	—
Jan 14, 2015 MForm 4 →	Jan 15, 4:46 pm EST	Joshua S BogerDirector	10,500	—	—	538,400	—
Jan 13, 2015 MForm 4 →	Jan 15, 4:48 pm EST	Paul M SilvaSVP & Corp Controller	1,125	—	—	2,250	—
Jan 9, 2015 MForm 4 →	Jan 13, 4:21 pm EST	Amit SachdevEVP, Policy, Access & Value	12,000	—	—	5,375	—
Jan 9, 2015 MForm 4 →	Jan 13, 4:19 pm EST	Wayne Joseph RileyDirector	10,000	—	—	0	—
Jan 9, 2015 MForm 4 →	Jan 13, 4:17 pm EST	Bruce I SachsDirector	9,861	—	—	139	—
Jan 7, 2015 MForm 4 →	Jan 9, 4:14 pm EST	Joshua S BogerDirector	10,500	—	—	542,800	—
Jan 2, 2015 MForm 4 →	Jan 6, 4:48 pm EST	Elaine UllianDirector	5,000	—	—	0	—
Jan 2, 2015 MForm 4 →	Jan 6, 4:45 pm EST	Jeffrey ChodakewitzEVP GMDA, CMO	2,291	—	—	45,835	—
Dec 31, 2014 MForm 4 →	Jan 5, 2015, 4:29 pm EST	Joshua S BogerDirector	10,500	—	—	547,200	—

Filed by this entity as an insider elsewhere — common stock

No reported common-stock activity in this period.

Filed by this entity as an insider elsewhere — derivatives (options, RSUs, warrants)

No reported derivative activity in this period.