Insider · CIK 0001197036

Bruce I Sachs

Period1M 3M 6M 1Y 2Y All datashares as filed — not split-adjusted

Open-market buys & salesbuys $0 · 0sales $5.3M · 5net −$5.3M

Reported trades — common stock

Trade	Reported (ET)	Company	Shares	Avg price	Total	Owned after	Δ stake	Flags
Aug 27, 2026 GForm 4 →	Aug 31, 4:20 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	6,000	—	—	39,000	—
Dec 28, 2018 GForm 4 →	Jan 2, 2019, 4:58 pm EST	VERTEX PHARMACEUTICALS INC / MAVRTX	10,000	—	—	13,011	—	plan?
Dec 6, 2018 MForm 4 →	Dec 7, 4:06 pm EST	VERTEX PHARMACEUTICALS INC / MAVRTX	10,000	$34.24	$342,400	23,011	—	plan?
Jun 1, 2018 ADForm 4 →	Jun 5, 5:32 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	3,989	—	—	13,011	—	plan?
Dec 20, 2017 GForm 5 →	Jan 17, 2018, 4:42 pm EST	VERTEX PHARMACEUTICALS INC / MAVRTX	10,000	—	—	13,398	—	plan?
Jun 1, 2017 ADForm 4 →	Jun 5, 6:00 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	5,129	—	—	23,398	—	plan?
Jun 1, 2016 AForm 4 →	Jun 3, 5:09 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	2,941	$0.01	$29	24,151	—	plan?
Aug 4, 2015 SForm 4 →	Aug 5, 4:18 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	10,000	$140.13	$1,401,300	21,210	−32.0%	plan?
Aug 4, 2015 MForm 4 →	Aug 5, 4:18 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	10,000	$34.24	$342,400	31,210	—	plan?
Mar 20, 2015 SForm 4 →	Mar 24, 6:04 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	10,000	$135.52	$1,355,190	21,210	−32.0%	plan?
Mar 20, 2015 MForm 4 →	Mar 24, 6:04 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	10,000	$29.89	$298,900	31,210	—	plan?
Mar 18, 2015 SForm 4 →	Mar 20, 4:19 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	10,000	$130.13	$1,301,300	21,210	−32.0%	plan?
Mar 18, 2015 MForm 4 →	Mar 20, 4:19 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	10,000	$29.89	$298,900	31,210	—	plan?
Jan 20, 2015 SForm 4 →	Jan 22, 5:24 pm EST	VERTEX PHARMACEUTICALS INC / MAVRTX	139	$125.00	$17,375	21,210	−0.65%	plan?
Jan 20, 2015 MForm 4 →	Jan 22, 5:24 pm EST	VERTEX PHARMACEUTICALS INC / MAVRTX	139	$28.40	$3,948	21,349	—	plan?
Jan 9, 2015 SForm 4 →	Jan 13, 4:17 pm EST	VERTEX PHARMACEUTICALS INC / MAVRTX	9,861	$125.04	$1,233,019	21,210	−31.7%	plan?
Jan 9, 2015 MForm 4 →	Jan 13, 4:17 pm EST	VERTEX PHARMACEUTICALS INC / MAVRTX	9,861	$28.40	$280,052	31,071	—	plan?

Reported trades — derivatives (options, RSUs, warrants)

Trade	Reported (ET)	Company	Shares	Avg price	Total	Owned after	Δ stake
Jul 15, 2026 AForm 4 →	Jul 17, 4:06 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	100	$475.28	$47,500	15,772	—
Jan 15, 2019 AForm 4 →	Jan 16, 4:52 pm EST	VERTEX PHARMACEUTICALS INC / MAVRTX	243	$184.90	$45,000	9,330	—
Dec 6, 2018 MForm 4 →	Dec 7, 4:06 pm EST	VERTEX PHARMACEUTICALS INC / MAVRTX	10,000	—	—	0	—
Oct 15, 2018 AForm 4 →	Oct 17, 9:44 am EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	251	$179.29	$45,000	9,087	—
Jul 16, 2018 AForm 4 →	Jul 18, 5:23 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	249	$180.97	$45,000	8,836	—
Jun 1, 2018 AForm 4 →	Jun 5, 5:32 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	5,417	—	—	8,587	—
Apr 16, 2018 AForm 4 →	Apr 18, 2:51 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	280	$160.89	$45,000	6,399	—
Jan 16, 2018 AForm 4 →	Jan 17, 4:43 pm EST	VERTEX PHARMACEUTICALS INC / MAVRTX	262	$157.50	$41,250	6,119	—
Oct 16, 2017 AForm 4 →	Oct 18, 5:31 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	265	$155.44	$41,250	5,858	—
Jul 17, 2017 AForm 4 →	Jul 19, 5:02 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	317	$130.15	$41,250	5,592	—
Jun 1, 2017 AForm 4 →	Jun 5, 6:00 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	8,236	—	—	5,275	—
Apr 17, 2017 AForm 4 →	Apr 19, 5:10 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	360	$114.58	$41,250	2,334	—
Jan 17, 2017 AForm 4 →	Jan 19, 12:33 pm EST	VERTEX PHARMACEUTICALS INC / MAVRTX	508	$81.16	$41,250	1,974	—
Oct 17, 2016 AForm 4 →	Oct 19, 2:33 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	516	$80.01	$41,250	1,466	—
Jul 15, 2016 AForm 4 →	Jul 19, 4:46 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	461	$89.45	$41,250	950	—
Jun 1, 2016 AForm 4 →	Jun 3, 5:09 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	7,073	—	—	7,073	—
Apr 15, 2016 AForm 4 →	Apr 19, 6:17 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	489	$87.60	$42,860	489	—
Aug 4, 2015 MForm 4 →	Aug 5, 4:18 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	10,000	—	—	10,000	—
Jun 1, 2015 AForm 4 →	Jun 3, 4:45 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	22,500	—	—	22,500	—
Mar 20, 2015 MForm 4 →	Mar 24, 6:04 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	10,000	—	—	0	—
Mar 18, 2015 MForm 4 →	Mar 20, 4:19 pm EDT	VERTEX PHARMACEUTICALS INC / MAVRTX	10,000	—	—	10,000	—
Jan 20, 2015 MForm 4 →	Jan 22, 5:24 pm EST	VERTEX PHARMACEUTICALS INC / MAVRTX	139	—	—	0	—
Jan 9, 2015 MForm 4 →	Jan 13, 4:17 pm EST	VERTEX PHARMACEUTICALS INC / MAVRTX	9,861	—	—	139	—