Form4insider filings, from the source

Company · CIK 0001813814 · SIC 2833 — Medicinal Chemicals & Botanical Products · Nasdaq

Definium Therapeutics, Inc. · DFTX

Insider activity reported against this company. All insider holders · On EDGAR ↗

1M3M6M1Y2YAll datashares as filed — not split-adjusted
Open-market buys & salesbuys $0 · 0sales $722k · 1net −$722k
$10k$10k$100k$100k$1M$1MbuyssalesJun 28Jul 13Jul 28Aug 13Aug 28Sep 13Sep 28

Reported at this company — common stock

TradeReported (ET)InsiderSharesAvg priceTotalOwned afterΔ stakeFlags
Sep 18, 2026 MForm 4 →Sep 18, 9:55 pm EDTCarol A ValloneDirector1,086$35.52$38,57522,296—
Sep 18, 2026 MForm 4 →Sep 18, 9:55 pm EDTAndreas KrebsDirector1,629$35.52$57,86221,402—
Sep 14, 2026 AForm 4 →Sep 14, 8:30 am EDTDaniel KarlinChief Medical Officer200,000——803,699—
Sep 14, 2026 AForm 4 →Sep 14, 8:30 am EDTMatthew T. WileyChief Commercial Officer125,000——362,133—
Sep 14, 2026 AForm 4 →Sep 14, 8:30 am EDTMark SullivanChief Legal Officer125,000——508,279—
Sep 14, 2026 AForm 4 →Sep 14, 8:30 am EDTBrandi RobertsChief Financial Officer125,000——397,905—
Sep 14, 2026 AForm 4 →Sep 14, 8:30 am EDTRobert BarrowChief Executive Officer, Director750,000——2,244,640—
Sep 3, 2026 SForm 4 →Sep 4, 9:30 pm EDTRobert BarrowChief Executive Officer, Director19,023$37.94$721,7331,494,640−1.26%10b5-1
Sep 2, 2026 AForm 4 →Sep 4, 9:30 pm EDTRobert BarrowChief Executive Officer, Director40,000——1,513,663—10b5-1
Aug 12, 2026 AForm 4 →Aug 12, 8:30 am EDTRobert BarrowChief Executive Officer, Director375,000——1,473,246—
Aug 12, 2026 AForm 4 →Aug 12, 8:30 am EDTDaniel KarlinChief Medical Officer100,000——603,282—
Aug 12, 2026 AForm 4 →Aug 12, 8:30 am EDTMark SullivanChief Legal Officer62,500——383,071—
Aug 12, 2026 AForm 4 →Aug 12, 8:30 am EDTMatthew T. WileyChief Commercial Officer62,500——237,133—
Aug 12, 2026 AForm 4 →Aug 12, 8:30 am EDTBrandi RobertsChief Financial Officer62,500——271,987—

Reported at this company — derivatives (options, RSUs, warrants)

TradeReported (ET)InsiderSharesAvg priceTotalOwned afterΔ stakeFlags
Sep 18, 2026 MForm 4 →Sep 18, 9:55 pm EDTCarol A ValloneDirector1,086——0—
Sep 18, 2026 MForm 4 →Sep 18, 9:55 pm EDTAndreas KrebsDirector1,629——0—