Company · CIK 0001610950 · SIC 8731 — Services-Commercial Physical & Biological Research

Syneos Health, Inc. · SYNH

Insider activity reported against this company. All insider holders · On EDGAR ↗

Period1M 3M 6M 1Y 2Y All datashares as filed — not split-adjusted

Open-market buys & salesbuys $225k · 3sales $2.39B · 80net −$2.39B

Reported at this company — common stock

Trade	Reported (ET)	Insider	Shares	Avg price	Total	Owned after	Δ stake	Flags
Jan 3, 2017 SForm 4 →	Jan 4, 4:02 pm EST	Gregory S RushExecutive VP and CFO	41,420	$51.90	$2,149,818	47,209	−46.7%	plan?
Jan 3, 2017 MForm 4 →	Jan 4, 4:02 pm EST	Gregory S RushExecutive VP and CFO	41,420	$10.92	$452,187	53,126	—	plan?
Oct 31, 2016 AForm 4 →	Nov 1, 5:37 pm EDT	Matthew E. MonaghanDirector	1,223	—	—	1,223	—	plan?
Oct 31, 2016 AForm 4 →	Nov 1, 4:01 pm EDT	Kenneth F MeyersDirector	1,223	—	—	1,223	—	plan?
Sep 30, 2016 SForm 4 →	Oct 3, 6:57 am EDT	Gregory S RushExecutive VP and CFO	35,503	$44.70	$1,586,913	47,209	−42.9%	plan?
Sep 30, 2016 MForm 4 →	Oct 3, 6:57 am EDT	Gregory S RushExecutive VP and CFO	35,503	$10.06	$357,160	82,712	—	plan?
Sep 27, 2016 MForm 4 →	Sep 28, 4:08 pm EDT	D. Jamie MacdonaldChief Executive Officer, Director	36,688	$14.83	$544,119	77,863	—	plan?
Sep 27, 2016 SForm 4 →	Sep 28, 4:08 pm EDT	D. Jamie MacdonaldChief Executive Officer, Director	53,970	$44.30	$2,391,062	58,927	−47.8%	plan?
Sep 26, 2016 SForm 4 →	Sep 28, 6:07 am EDT	Robert W BreckonDirector	12,197	$44.16	$538,624	3,364	−78.4%	plan?
Sep 26, 2016 MForm 4 →	Sep 28, 6:07 am EDT	Robert W BreckonDirector	7,600	$8.45	$64,220	15,561	—	plan?
Sep 19, 2016 PForm 4 →	Sep 20, 4:01 pm EDT	David F BurgstahlerDirector, 10% Owner	1,000	$43.19	$43,187	36,065	+2.85%	plan?
Sep 15, 2016 AForm 4 →	Sep 16, 4:03 pm EDT	David F BurgstahlerDirector, 10% Owner	1,729	—	—	35,065	—	plan?
Sep 15, 2016 AForm 4 →	Sep 16, 8:05 am EDT	Gregory S RushExecutive VP and CFO	29,110	—	—	47,209	—	plan?
Sep 15, 2016 AForm 4 →	Sep 16, 8:01 am EDT	Michael GibertiniPresident Clinical Development	29,110	—	—	47,639	—	plan?
Sep 14, 2016 SForm 4 →	Sep 16, 8:03 am EDT	Christopher L GaenzleCAO, GC & Sec	4,734	$43.14	$204,234	14,518	−24.6%	plan?
Sep 14, 2016 AMForm 4 →	Sep 16, 8:03 am EDT	Christopher L GaenzleCAO, GC & Sec	31,516	$10.06	$47,624	41,300	—	plan?
Aug 24, 2016 JForm 4 →	Sep 1, 4:01 pm EDT	David F BurgstahlerDirector	36,984	—	—	3,648	—	plan? late
Aug 24, 2016 JForm 4 →	Aug 31, 4:03 pm EDT	Charles C Harwood Jr.Director	8,753	—	—	26,294	—	plan? late
Aug 17, 2016 SForm 4 →	Aug 18, 4:37 pm EDT	Alistair MacdonaldChief Operating Officer	8,828	$43.80	$386,666	54,229	−14.0%	plan?
Aug 17, 2016 MForm 4 →	Aug 18, 4:37 pm EDT	Alistair MacdonaldChief Operating Officer	8,828	$10.57	$93,312	63,057	—	plan?
Aug 4, 2016 SForm 4 →	Aug 5, 3:28 pm EDT	Teachers Pension Plan Board Ontario +1Director, 10% Owner	2,445,591	$42.06	$102,861,557	3,944,174	−38.3%	plan?
Aug 4, 2016 SForm 4 →	Aug 5, 3:25 pm EDT	Avista Capital Partners II GP, LLC +510% Owner	2,554,409	$42.06	$107,438,443	4,119,676	−38.3%	plan?
Aug 2, 2016 SForm 4 →	Aug 3, 4:04 pm EDT	D. Jamie MacdonaldChief Executive Officer, Director	31,279	$43.00	$1,344,997	76,209	−29.1%	plan?
Aug 2, 2016 MForm 4 →	Aug 3, 4:04 pm EDT	D. Jamie MacdonaldChief Executive Officer, Director	31,279	$10.57	$330,619	107,488	—	plan?
Aug 1, 2016 AForm 4 →	Aug 2, 4:04 pm EDT	Alistair MacdonaldChief Operating Officer	35,553	—	—	54,229	—	plan?
Aug 1, 2016 SForm 4 →	Aug 2, 4:01 pm EDT	Robert W BreckonDirector	108	$42.00	$4,536	7,961	−1.34%	plan?
Jul 28, 2016 SForm 4 →	Jul 29, 9:08 am EDT	Gregory S RushExecutive VP and CFO	4,066	$45.23	$183,889	18,099	−18.3%	plan?
Jul 28, 2016 MForm 4 →	Jul 29, 9:08 am EDT	Gregory S RushExecutive VP and CFO	4,066	$40.12	$163,128	22,165	—	plan?
Jul 20, 2016 SForm 4 →	Jul 21, 4:43 pm EDT	D. Jamie MacdonaldChief Executive Officer, Director	100,593	$43.00	$4,325,499	76,209	−56.9%	plan?
Jul 20, 2016 MForm 4 →	Jul 21, 4:43 pm EDT	D. Jamie MacdonaldChief Executive Officer, Director	100,593	$10.57	$1,063,268	147,216	—	plan?
Jul 15, 2016 SForm 4 →	Jul 18, 8:40 am EDT	Gregory S RushExecutive VP and CFO	5,917	$41.50	$245,538	18,099	−24.6%	plan?
Jul 15, 2016 MForm 4 →	Jul 18, 8:40 am EDT	Gregory S RushExecutive VP and CFO	5,917	$16.06	$95,027	24,016	—	plan?
Jul 11, 2016 SForm 4 →	Jul 12, 4:01 pm EDT	Alistair MacdonaldChief Operating Officer	9,468	$40.19	$380,500	18,676	−33.6%	plan?
Jul 11, 2016 MForm 4 →	Jul 12, 4:01 pm EDT	Alistair MacdonaldChief Operating Officer	9,468	$16.06	$152,056	28,144	—	plan?
Jul 11, 2016 SForm 4 →	Jul 12, 4:00 pm EDT	Christopher L GaenzleCAO, GC & Sec	21,918	$40.20	$881,077	14,518	−60.2%	plan?
Jul 11, 2016 MForm 4 →	Jul 12, 4:00 pm EDT	Christopher L GaenzleCAO, GC & Sec	20,701	$15.29	$316,504	18,641	—	plan?
Jul 1, 2016 SForm 4 →	Jul 5, 4:01 pm EDT	Robert W BreckonDirector	421	$37.97	$15,985	8,069	−4.96%	plan?
Jul 1, 2016 SForm 4 →	Jul 5, 8:17 am EDT	Gregory S RushExecutive VP and CFO	1,358	$37.97	$51,563	18,099	−6.98%	plan?
Jun 30, 2016 FForm 4 →	Jul 5, 8:17 am EDT	Gregory S RushExecutive VP and CFO	675	$38.13	$25,738	19,457	—	plan?
Jun 30, 2016 FForm 4 →	Jul 1, 4:10 pm EDT	Christopher L GaenzleCAO, GC & Sec	606	$38.13	$23,107	15,735	—	plan?
Jun 30, 2016 FForm 4 →	Jul 1, 4:09 pm EDT	Michael GibertiniPresident Clinical Development	883	$38.13	$33,669	18,529	—	plan?
Jun 30, 2016 FForm 4 →	Jul 1, 4:07 pm EDT	Alistair MacdonaldChief Operating Officer	1,023	$38.13	$39,007	18,676	—	plan?
Jun 30, 2016 FForm 4 →	Jul 1, 4:05 pm EDT	D. Jamie MacdonaldChief Executive Officer, Director	3,017	$38.13	$115,038	76,209	—	plan?
Jun 14, 2016 SForm 4 →	Jun 16, 9:03 am EDT	Christopher L GaenzleCAO, GC & Sec	7,702	$40.14	$309,140	16,341	−32.0%	plan?
Jun 14, 2016 MForm 4 →	Jun 16, 9:03 am EDT	Christopher L GaenzleCAO, GC & Sec	7,702	$14.76	$113,658	20,269	—	plan?
Jun 6, 2016 SForm 4 →	Jun 7, 4:04 pm EDT	Michael GibertiniPresident Clinical Development	213,966	$43.11	$9,223,171	19,412	−91.7%	plan?
Jun 6, 2016 MForm 4 →	Jun 7, 4:04 pm EDT	Michael GibertiniPresident Clinical Development	186,096	$9.34	$1,738,615	65,034	—	plan?
Jun 1, 2016 SForm 4 →	Jun 3, 4:07 pm EDT	Robert W BreckonDirector	11,691	$43.53	$508,938	8,490	−57.9%	plan?
Jun 1, 2016 MForm 4 →	Jun 3, 4:07 pm EDT	Robert W BreckonDirector	9,518	$8.45	$80,427	11,134	—	plan?
May 24, 2016 AForm 4 →	May 25, 4:06 pm EDT	James T. OgleDirector	2,231	—	—	180,617	—	plan?
May 24, 2016 AForm 4 →	May 25, 4:04 pm EDT	David Y NortonDirector	2,231	—	—	4,295	—	plan?
May 24, 2016 AForm 4 →	May 25, 4:03 pm EDT	Richard N KenderDirector	2,231	—	—	4,455	—	plan?
May 24, 2016 AForm 4 →	May 25, 4:01 pm EDT	Charles C Harwood Jr.Director	2,231	—	—	17,541	—	plan?
May 24, 2016 AForm 4 →	May 25, 4:00 pm EDT	Robert W BreckonDirector	2,231	—	—	10,663	—	plan?
May 6, 2016 SForm 4 →	May 9, 5:03 pm EDT	Teachers Pension Plan Board Ontario +1Director, 10% Owner	3,912,946	$45.12	$176,552,124	6,389,765	−38.0%	plan?
May 6, 2016 SForm 4 →	May 9, 4:22 pm EDT	Avista Capital Partners II GP, LLC +510% Owner	4,087,054	$45.12	$184,407,876	6,674,085	−38.0%	plan?
Apr 18, 2016 SForm 4 →	Apr 19, 4:01 pm EDT	James T. OgleDirector	114,806	$50.00	$5,740,300	178,386	−39.2%	plan?
Apr 18, 2016 MForm 4 →	Apr 19, 4:01 pm EDT	James T. OgleDirector	114,806	$8.45	$970,111	293,192	—	plan?
Apr 12, 2016 SForm 4 →	Apr 14, 8:26 am EDT	D. Jamie MacdonaldChief Executive Officer, Director	94,675	$48.00	$4,544,400	79,226	−54.4%	plan?
Apr 12, 2016 MForm 4 →	Apr 14, 8:26 am EDT	D. Jamie MacdonaldChief Executive Officer, Director	94,675	$10.57	$1,000,715	114,729	—	plan?
Apr 1, 2016 SForm 4 →	Apr 4, 6:29 pm EDT	Michael GibertiniPresident Clinical Development	9,000	$40.78	$367,038	47,282	−16.0%	plan?
Apr 1, 2016 MForm 4 →	Apr 4, 6:29 pm EDT	Michael GibertiniPresident Clinical Development	9,000	$8.45	$76,050	56,282	—	plan?
Mar 1, 2016 SForm 4 →	Mar 2, 4:06 pm EST	Michael GibertiniPresident Clinical Development	9,000	$39.85	$358,677	47,282	−16.0%	plan?
Mar 1, 2016 MForm 4 →	Mar 2, 4:06 pm EST	Michael GibertiniPresident Clinical Development	9,000	$8.45	$76,050	56,282	—	plan?
Feb 4, 2016 MForm 4 →	Feb 5, 4:18 pm EST	Robert W BreckonDirector	2,787	$8.45	$23,550	11,219	—	plan?
Feb 4, 2016 SForm 4 →	Feb 5, 4:18 pm EST	Robert W BreckonDirector	3,882	$40.03	$155,381	8,432	−31.5%	plan?
Feb 1, 2016 SForm 4 →	Feb 2, 4:02 pm EST	Michael GibertiniPresident Clinical Development	9,000	$40.57	$365,152	47,282	−16.0%	plan?
Feb 1, 2016 MForm 4 →	Feb 2, 4:02 pm EST	Michael GibertiniPresident Clinical Development	9,000	$8.45	$76,050	56,282	—	plan?
Feb 1, 2016 SForm 4 →	Feb 2, 4:00 pm EST	Gregory S RushExecutive VP and CFO	17,752	$40.27	$714,861	20,132	−46.9%	plan?
Feb 1, 2016 MForm 4 →	Feb 2, 4:00 pm EST	Gregory S RushExecutive VP and CFO	17,752	$16.06	$285,097	37,884	—	plan?
Jan 19, 2016 AForm 4 →	Jan 21, 4:09 pm EST	Michael GibertiniPresident Clinical Development	11,000	—	—	47,282	—	plan?
Jan 19, 2016 AForm 4 →	Jan 21, 4:08 pm EST	Alistair MacdonaldChief Operating Officer	11,000	—	—	19,699	—	plan?
Jan 19, 2016 AForm 4 →	Jan 21, 4:06 pm EST	D. Jamie MacdonaldChief Executive Officer, Director	40,000	—	—	79,226	—	plan?
Jan 19, 2016 AForm 4 →	Jan 21, 4:05 pm EST	Christopher L GaenzleCAO, GC & Sec	9,050	—	—	16,341	—	plan?
Jan 19, 2016 AForm 4 →	Jan 21, 4:04 pm EST	Gregory S RushExecutive VP and CFO	12,000	—	—	20,132	—	plan?
Jan 4, 2016 SForm 4 →	Jan 6, 7:35 am EST	Michael GibertiniPresident Clinical Development	9,000	$46.83	$421,493	36,282	−19.9%	plan?
Jan 4, 2016 MForm 4 →	Jan 6, 7:35 am EST	Michael GibertiniPresident Clinical Development	9,000	$8.45	$76,050	45,282	—	plan?
Dec 31, 2015 SForm 4 →	Jan 4, 2016, 4:03 pm EST	Gregory S RushExecutive VP and CFO	35,503	$48.17	$1,710,210	8,132	−81.4%	plan?
Dec 31, 2015 MForm 4 →	Jan 4, 2016, 4:03 pm EST	Gregory S RushExecutive VP and CFO	35,503	$10.06	$357,160	43,635	—	plan?
Dec 31, 2015 SForm 4 →	Jan 4, 2016, 4:02 pm EST	Christopher L GaenzleCAO, GC & Sec	9,468	$48.18	$456,207	7,291	−56.5%	plan?
Dec 31, 2015 MForm 4 →	Jan 4, 2016, 4:02 pm EST	Christopher L GaenzleCAO, GC & Sec	9,468	$10.32	$97,662	12,025	—	plan?
Dec 31, 2015 MForm 4 →	Jan 4, 2016, 4:00 pm EST	Alistair MacdonaldChief Operating Officer	112,617	$11.37	$1,280,069	37,103	—	plan?
Dec 31, 2015 SForm 4 →	Jan 4, 2016, 4:00 pm EST	Alistair MacdonaldChief Operating Officer	159,599	$47.46	$7,574,735	8,699	−94.8%	plan?
Dec 29, 2015 SForm 4 →	Dec 31, 7:47 am EST	James T. OgleDirector	9,717	$50.06	$486,452	183,386	−5.03%	plan?
Dec 29, 2015 MForm 4 →	Dec 31, 7:47 am EST	James T. OgleDirector	9,717	$8.45	$82,109	193,103	—	plan?
Dec 7, 2015 SForm 4 →	Dec 9, 4:02 pm EST	Christopher L GaenzleCAO, GC & Sec	25,185	$41.78	$1,052,338	7,291	−77.5%	plan?
Dec 7, 2015 MForm 4 →	Dec 9, 4:02 pm EST	Christopher L GaenzleCAO, GC & Sec	25,185	$10.34	$260,497	32,476	—	plan?
Dec 7, 2015 SForm 4 →	Dec 9, 4:00 pm EST	Gregory S RushExecutive VP and CFO	81,035	$45.13	$3,656,981	8,132	−90.9%	plan?
Dec 7, 2015 MForm 4 →	Dec 9, 4:00 pm EST	Gregory S RushExecutive VP and CFO	81,035	$10.06	$815,212	89,167	—	plan?
Dec 7, 2015 SForm 4 →	Dec 9, 10:38 am EST	Alistair MacdonaldChief Operating Officer	42,959	$44.63	$1,917,397	55,681	−43.6%	plan?
Dec 7, 2015 MForm 4 →	Dec 9, 10:38 am EST	Alistair MacdonaldChief Operating Officer	42,959	$8.45	$363,004	98,640	—	plan?
Dec 7, 2015 SForm 4 →	Dec 8, 7:22 pm EST	Teachers Pension Plan Board Ontario +1Director, 10% Owner	4,402,063	$45.00	$198,092,835	10,302,711	−29.9%	plan?
Dec 7, 2015 SForm 4 →	Dec 8, 5:14 pm EST	Avista Capital Partners II GP, LLC +510% Owner	4,597,937	$45.00	$206,907,165	10,761,139	−29.9%	plan?
Dec 1, 2015 SForm 4 →	Dec 3, 8:44 am EST	Michael GibertiniPresident Clinical Development	9,000	$46.52	$418,662	36,282	−19.9%	plan?
Dec 1, 2015 MForm 4 →	Dec 3, 8:44 am EST	Michael GibertiniPresident Clinical Development	9,000	$8.45	$76,050	45,282	—	plan?
Nov 2, 2015 SForm 4 →	Nov 3, 4:01 pm EST	Michael GibertiniPresident Clinical Development	9,000	$41.70	$375,300	36,282	−19.9%	plan?
Nov 2, 2015 MForm 4 →	Nov 3, 4:01 pm EST	Michael GibertiniPresident Clinical Development	9,000	$8.45	$76,050	45,282	—	plan?
Sep 28, 2015 SForm 4 →	Sep 29, 4:02 pm EDT	Alistair MacdonaldChief Operating Officer	44,522	$39.93	$1,777,629	55,681	−44.4%	plan?
Sep 28, 2015 MForm 4 →	Sep 29, 4:02 pm EDT	Alistair MacdonaldChief Operating Officer	44,522	$8.45	$376,211	100,203	—	plan?
Sep 14, 2015 SForm 4 →	Sep 16, 8:20 am EDT	Gregory S RushExecutive VP and CFO	32,426	$45.06	$1,460,999	8,132	−79.9%	plan?

Reported at this company — derivatives (options, RSUs, warrants)

Trade	Reported (ET)	Insider	Shares	Avg price	Total	Owned after	Δ stake	Flags
Feb 13, 2019 MForm 4 →	Feb 15, 7:34 am EST	Alistair MacdonaldChief Executive Officer, Director	8,143	—	—	0	—
Feb 5, 2019 MForm 4 →	Feb 7, 8:29 am EST	Alistair MacdonaldChief Executive Officer, Director	6,697	—	—	8,143	—
May 7, 2018 AForm 4 →	May 9, 6:59 am EDT	Jason M. MeggsChief Financial Officer	12,950	—	—	12,950	—
Feb 15, 2018 AForm 4 →	Feb 20, 4:00 pm EST	Alistair MacdonaldChief Executive Officer, Director	79,470	—	—	79,470	—
Sep 1, 2017 MForm 4 →	Sep 5, 8:38 pm EDT	Gregory S RushChief Financial Officer	98,739	—	—	8,132	—
Sep 1, 2017 MForm 4 →	Sep 5, 4:02 pm EDT	Christopher L GaenzleCAO, GC & Sec	42,601	—	—	0	—
Aug 30, 2017 MForm 4/A →	Sep 5, 8:30 pm EDT	Gregory S RushChief Financial Officer	41,420	—	—	23,668	—
Aug 30, 2017 MForm 4 →	Sep 1, 7:10 pm EDT	Gregory S RushChief Financial Officer	41,420	—	—	23,668	—	amended
Aug 17, 2017 MForm 4 →	Aug 21, 7:39 am EDT	Alistair MacdonaldChief Executive Officer, Director	8,828	—	—	8,828	—
Aug 10, 2017 AForm 4 →	Aug 14, 7:38 am EDT	Christopher L GaenzleCAO, GC & Sec	11,475	—	—	11,475	—
Aug 10, 2017 AForm 4 →	Aug 14, 7:37 am EDT	Gregory S RushExecutive VP and CFO	11,803	—	—	11,803	—
Aug 10, 2017 AForm 4 →	Aug 14, 7:36 am EDT	Michael Adam BellExec Chair & Pres, Comm Div, Director	29,143	—	—	29,143	—
Aug 10, 2017 AForm 4 →	Aug 14, 7:34 am EDT	Alistair MacdonaldChief Executive Officer, Director	36,429	—	—	36,429	—
Aug 1, 2017 MForm 4 →	Aug 3, 8:12 am EDT	Alistair MacdonaldChief Executive Officer, Director	48,921	—	—	0	—
Aug 1, 2017 MForm 4 →	Aug 2, 4:15 pm EDT	Michael GibertiniOther	32,351	—	—	0	—
Aug 1, 2017 MForm 4 →	Aug 2, 4:12 pm EDT	Christopher L GaenzleCAO, GC & Sec	27,495	—	—	0	—
Aug 1, 2017 MForm 4 →	Aug 2, 4:11 pm EDT	Gregory S RushExecutive VP and CFO	35,291	—	—	0	—
Jun 30, 2017 MForm 4 →	Jul 5, 7:42 am EDT	Christopher L GaenzleCAO, GC & Sec	5,917	—	—	23,668	—
Jun 30, 2017 MForm 4 →	Jul 5, 7:40 am EDT	Alistair MacdonaldChief Executive Officer, Director	9,467	—	—	37,868	—
May 1, 2017 MForm 4 →	May 2, 4:01 pm EDT	Alistair MacdonaldChief Executive Officer, Director	9,467	—	—	37,868	—
Apr 3, 2017 MForm 4 →	Apr 4, 4:00 pm EDT	Christopher L GaenzleCAO, GC & Sec	4,733	—	—	4,733	—
Mar 3, 2017 MForm 4 →	Mar 6, 7:14 am EST	Alistair MacdonaldChief Executive Officer, Director	8,828	—	—	17,656	—
Jan 27, 2017 AForm 4 →	Jan 30, 4:03 pm EST	Christopher L GaenzleCAO, GC & Sec	13,920	—	—	13,920	—
Jan 27, 2017 AForm 4 →	Jan 30, 4:02 pm EST	Michael GibertiniChief Operating Officer	15,851	—	—	15,851	—
Jan 27, 2017 AForm 4 →	Jan 30, 4:01 pm EST	Gregory S RushExecutive VP and CFO	17,291	—	—	17,291	—
Jan 27, 2017 AForm 4 →	Jan 30, 4:00 pm EST	Alistair MacdonaldChief Executive Officer, Director	32,421	—	—	32,421	—
Jan 19, 2017 MForm 4 →	Jan 23, 6:44 am EST	Gregory S RushExecutive VP and CFO	1,334	—	—	3,999	—
Jan 5, 2017 MForm 4 →	Jan 6, 4:02 pm EST	Alistair MacdonaldChief Executive Officer, Director	14,840	—	—	14,840	—
Jan 3, 2017 MForm 4 →	Jan 4, 4:03 pm EST	Christopher L GaenzleCAO, GC & Sec	15,383	—	—	9,466	—
Jan 3, 2017 MForm 4 →	Jan 4, 4:02 pm EST	Gregory S RushExecutive VP and CFO	41,420	—	—	29,585	—
Sep 30, 2016 MForm 4 →	Oct 3, 6:57 am EDT	Gregory S RushExecutive VP and CFO	35,503	—	—	142,011	—
Sep 27, 2016 MForm 4 →	Sep 28, 4:08 pm EDT	D. Jamie MacdonaldChief Executive Officer, Director	36,688	—	—	75,738	—
Sep 26, 2016 MForm 4 →	Sep 28, 6:07 am EDT	Robert W BreckonDirector	7,600	—	—	0	—
Sep 14, 2016 MForm 4 →	Sep 16, 8:03 am EDT	Christopher L GaenzleCAO, GC & Sec	4,734	—	—	18,933	—
Aug 17, 2016 MForm 4 →	Aug 18, 4:37 pm EDT	Alistair MacdonaldChief Operating Officer	8,828	—	—	26,484	—
Aug 2, 2016 MForm 4 →	Aug 3, 4:04 pm EDT	D. Jamie MacdonaldChief Executive Officer, Director	31,279	—	—	59,170	—
Aug 1, 2016 AForm 4 →	Aug 2, 4:04 pm EDT	Alistair MacdonaldChief Operating Officer	35,553	—	—	35,553	—
Jul 28, 2016 MForm 4 →	Jul 29, 9:08 am EDT	Gregory S RushExecutive VP and CFO	4,066	—	—	12,198	—
Jul 20, 2016 MForm 4 →	Jul 21, 4:43 pm EDT	D. Jamie MacdonaldChief Executive Officer, Director	100,593	—	—	71,004	—
Jul 15, 2016 MForm 4 →	Jul 18, 8:40 am EDT	Gregory S RushExecutive VP and CFO	5,917	—	—	35,502	—
Jul 11, 2016 MForm 4 →	Jul 12, 4:01 pm EDT	Alistair MacdonaldChief Operating Officer	9,468	—	—	56,802	—
Jul 11, 2016 MForm 4 →	Jul 12, 4:00 pm EDT	Christopher L GaenzleCAO, GC & Sec	20,701	—	—	14,199	—
Jun 14, 2016 MForm 4 →	Jun 16, 9:03 am EDT	Christopher L GaenzleCAO, GC & Sec	7,702	—	—	53,297	—
Jun 6, 2016 MForm 4 →	Jun 7, 4:04 pm EDT	Michael GibertiniPresident Clinical Development	186,096	—	—	41,419	—
Jun 1, 2016 MForm 4 →	Jun 3, 4:07 pm EDT	Robert W BreckonDirector	9,518	—	—	7,600	—
Apr 18, 2016 MForm 4 →	Apr 19, 4:01 pm EDT	James T. OgleDirector	114,806	—	—	0	—
Apr 12, 2016 MForm 4 →	Apr 14, 8:26 am EDT	D. Jamie MacdonaldChief Executive Officer, Director	94,675	—	—	142,011	—
Apr 1, 2016 MForm 4 →	Apr 4, 6:29 pm EDT	Michael GibertiniPresident Clinical Development	9,000	—	—	205,644	—
Mar 1, 2016 MForm 4 →	Mar 2, 4:06 pm EST	Michael GibertiniPresident Clinical Development	9,000	—	—	214,644	—
Feb 4, 2016 MForm 4 →	Feb 5, 4:18 pm EST	Robert W BreckonDirector	2,787	—	—	9,047	—
Feb 1, 2016 MForm 4 →	Feb 2, 4:02 pm EST	Michael GibertiniPresident Clinical Development	9,000	—	—	223,644	—
Feb 1, 2016 MForm 4 →	Feb 2, 4:00 pm EST	Gregory S RushExecutive VP and CFO	17,752	—	—	41,419	—
Jan 19, 2016 AForm 4 →	Jan 21, 4:09 pm EST	Michael GibertiniPresident Clinical Development	21,389	—	—	16,500	—
Jan 19, 2016 AForm 4 →	Jan 21, 4:08 pm EST	Alistair MacdonaldChief Operating Officer	21,389	—	—	16,500	—
Jan 19, 2016 AForm 4 →	Jan 21, 4:06 pm EST	D. Jamie MacdonaldChief Executive Officer, Director	77,778	—	—	60,000	—
Jan 19, 2016 AForm 4 →	Jan 21, 4:05 pm EST	Christopher L GaenzleCAO, GC & Sec	17,597	—	—	13,575	—
Jan 19, 2016 AForm 4 →	Jan 21, 4:04 pm EST	Gregory S RushExecutive VP and CFO	23,333	—	—	18,000	—
Jan 4, 2016 MForm 4 →	Jan 6, 7:35 am EST	Michael GibertiniPresident Clinical Development	9,000	—	—	232,644	—
Dec 31, 2015 MForm 4 →	Jan 4, 2016, 4:03 pm EST	Gregory S RushExecutive VP and CFO	35,503	—	—	177,514	—
Dec 31, 2015 MForm 4 →	Jan 4, 2016, 4:02 pm EST	Christopher L GaenzleCAO, GC & Sec	9,468	—	—	18,933	—
Dec 31, 2015 MForm 4 →	Jan 4, 2016, 4:00 pm EST	Alistair MacdonaldChief Operating Officer	112,617	—	—	66,270	—
Dec 29, 2015 MForm 4 →	Dec 31, 7:47 am EST	James T. OgleDirector	9,717	—	—	114,806	—
Dec 7, 2015 MForm 4 →	Dec 9, 4:02 pm EST	Christopher L GaenzleCAO, GC & Sec	25,185	—	—	28,401	—
Dec 7, 2015 MForm 4 →	Dec 9, 4:00 pm EST	Gregory S RushExecutive VP and CFO	81,035	—	—	213,017	—
Dec 7, 2015 MForm 4 →	Dec 9, 10:38 am EST	Alistair MacdonaldChief Operating Officer	42,959	—	—	60,921	—
Dec 1, 2015 MForm 4 →	Dec 3, 8:44 am EST	Michael GibertiniPresident Clinical Development	9,000	—	—	241,644	—
Nov 2, 2015 MForm 4 →	Nov 3, 4:01 pm EST	Michael GibertiniPresident Clinical Development	9,000	—	—	250,644	—
Sep 28, 2015 MForm 4 →	Sep 29, 4:02 pm EDT	Alistair MacdonaldChief Operating Officer	44,522	—	—	103,880	—
Sep 14, 2015 MForm 4 →	Sep 16, 8:20 am EDT	Gregory S RushExecutive VP and CFO	32,426	—	—	294,052	—
Aug 31, 2015 MForm 4 →	Sep 1, 4:06 pm EDT	Christopher L GaenzleCAO, GC & Sec	17,421	—	—	39,594	—
Aug 12, 2015 MForm 4 →	Aug 14, 8:29 am EDT	Robert W BreckonDirector	3,669	—	—	8,071	—
Aug 12, 2015 MForm 4 →	Aug 14, 8:25 am EDT	D. Jamie MacdonaldChief Executive Officer, Director	116,650	—	—	179,207	—
Jun 30, 2015 AForm 4 →	Jul 2, 8:44 am EDT	Christopher L GaenzleCAO, GC & Sec	14,581	—	—	14,581	—
Jun 30, 2015 AForm 4 →	Jul 2, 8:41 am EDT	Michael GibertiniPresident Clinical Development	16,825	—	—	16,825	—
Jun 30, 2015 AForm 4 →	Jul 2, 8:40 am EDT	Gregory S RushExecutive VP and CFO	16,264	—	—	16,264	—
Jun 30, 2015 AForm 4 →	Jul 2, 8:39 am EDT	Alistair MacdonaldChief Operating Officer	17,398	—	—	17,398	—
Jun 30, 2015 AForm 4 →	Jul 2, 8:37 am EDT	D. Jamie MacdonaldChief Executive Officer, Director	50,474	—	—	50,474	—
Jun 5, 2015 AForm 4 →	Jun 9, 9:11 am EDT	Richard N KenderDirector	3,100	—	—	3,100	—
Jun 5, 2015 AForm 4 →	Jun 9, 8:47 am EDT	David Y NortonDirector	2,675	—	—	2,675	—
Jun 5, 2015 AForm 4 →	Jun 9, 8:28 am EDT	James T. OgleDirector	3,401	—	—	3,401	—
Jun 5, 2015 AForm 4 →	Jun 9, 8:26 am EDT	Robert W BreckonDirector	3,401	—	—	3,401	—
Jun 5, 2015 AForm 4 →	Jun 9, 8:24 am EDT	Charles C Harwood Jr.Director	3,401	—	—	3,401	—
May 11, 2015 MForm 4 →	May 13, 8:24 am EDT	Gregory S RushExecutive VP and CFO	2,301	—	—	326,478	—
May 11, 2015 MForm 4 →	May 13, 8:21 am EDT	James T. OgleDirector	4,191	—	—	47,187	—
May 11, 2015 MForm 4 →	May 13, 8:19 am EDT	Robert W BreckonDirector	485	—	—	11,740	—
May 7, 2015 MForm 4 →	May 11, 8:17 am EDT	Gregory S RushExecutive VP and CFO	26,250	—	—	328,779	—
May 7, 2015 MForm 4 →	May 11, 8:12 am EDT	Robert W BreckonDirector	5,526	—	—	12,225	—
May 7, 2015 MForm 4 →	May 11, 8:07 am EDT	James T. OgleDirector	47,814	—	—	47,962	—
Feb 3, 2015 AForm 4 →	Feb 4, 4:40 pm EST	David Y NortonDirector	1,451	—	—	1,451	—