Company · CIK 0001501697 · SIC 2836 — Biological Products, (No Diagnostic Substances) · Nasdaq

X4 Pharmaceuticals, Inc · XFOR

Insider activity reported against this company. All insider holders · On EDGAR ↗

Period1M 3M 6M 1Y 2Y All datashares as filed — not split-adjusted

Open-market buys & salesbuys $33.2M · 9sales $356k · 3net $32.8M

Reported at this company — common stock

Trade	Reported (ET)	Insider	Shares	Avg price	Total	Owned after	Δ stake	Flags
Aug 12, 2026 SForm 4 →	Aug 13, 4:13 pm EDT	John VolponePresident	24,576	$4.44	$109,228	265,305	−8.48%
Aug 12, 2026 SForm 4 →	Aug 13, 4:10 pm EDT	Adam R CraigExecutive Chairman, Director	47,436	$4.44	$210,829	328,651	−12.6%
Jun 30, 2026 SForm 4 →	Jul 1, 4:23 pm EDT	David KirskeChief Financial Officer	8,543	$4.26	$36,428	167,750	−4.85%
Nov 27, 2018 AForm 4 →	Nov 28, 9:50 pm EST	Michael GrayPresident, CEO and CFO, Director	250,000	—	—	250,000	—	plan?
Nov 20, 2017 PForm 4 →	Nov 20, 9:56 pm EST	EMBL Technology Fund II GmbH & Co. KG +410% Owner	20,000	$10.00	$200,000	370,454	+5.71%	plan?
Nov 20, 2017 CForm 4 →	Nov 20, 9:56 pm EST	EMBL Technology Fund II GmbH & Co. KG +410% Owner	350,454	—	—	350,454	—	plan?
Nov 20, 2017 CForm 4 →	Nov 20, 7:09 pm EST	Bill & Melinda Gates Foundation10% Owner	722,179	—	—	722,179	—	plan?
Nov 20, 2017 PForm 4 →	Nov 20, 6:15 pm EST	NeoMed Innovation V L.P. +210% Owner	300,000	$10.00	$3,000,000	867,639	+52.9%	plan?
Nov 20, 2017 CForm 4 →	Nov 20, 6:15 pm EST	NeoMed Innovation V L.P. +210% Owner	567,639	—	—	567,639	—	plan?
Nov 20, 2017 CForm 4 →	Nov 20, 5:43 pm EST	GV 2016 GP, L.L.C. +310% Owner	451,362	—	—	451,362	—	plan?
Nov 20, 2017 PForm 4 →	Nov 20, 5:43 pm EST	Claudio NessiDirector	300,000	$10.00	$3,000,000	867,639	+52.9%	plan?
Nov 20, 2017 CForm 4 →	Nov 20, 5:43 pm EST	Claudio NessiDirector	567,639	—	—	567,639	—	plan?
Nov 20, 2017 CForm 4 →	Nov 20, 5:42 pm EST	Anna-Maria & Stephen Kellen Foundation, Inc.10% Owner	124,381	—	—	124,381	—	plan?
Nov 20, 2017 CForm 4 →	Nov 20, 5:38 pm EST	Section 32 Fund 1, LP +210% Owner	451,362	—	—	451,362	—	plan?
Nov 20, 2017 PForm 4 →	Nov 20, 5:37 pm EST	SVLSF V, LLC +410% Owner	500,000	$10.00	$5,000,000	1,868,961	+36.5%	plan?
Nov 20, 2017 CForm 4 →	Nov 20, 5:37 pm EST	SVLSF V, LLC +410% Owner	1,368,961	—	—	1,368,961	—	plan?
Nov 20, 2017 PForm 4 →	Nov 20, 5:36 pm EST	Terrance McGuireDirector, 10% Owner	500,000	$10.00	$5,000,000	18,031	—	plan?
Nov 20, 2017 CForm 4 →	Nov 20, 5:36 pm EST	Terrance McGuireDirector, 10% Owner	1,368,957	—	—	13,206	—	plan?
Nov 20, 2017 PForm 4 →	Nov 20, 5:32 pm EST	Tillman U. GerngrossDirector	200,000	$10.00	$2,000,000	392,821	+104%	plan?
Nov 20, 2017 CForm 4 →	Nov 20, 5:32 pm EST	Tillman U. GerngrossDirector	90,272	—	—	192,821	—	plan?
Nov 20, 2017 CForm 4 →	Nov 20, 5:32 pm EST	ORBIMED ADVISORS LLC +210% Owner	1,868,966	$10.00	$5,000,000	1,868,966	—	plan?
Nov 20, 2017 PForm 4 →	Nov 20, 5:31 pm EST	Carl L GordonDirector, 10% Owner	500,000	$10.00	$5,000,000	1,868,966	+36.5%	plan?
Nov 20, 2017 CForm 4 →	Nov 20, 5:31 pm EST	Carl L GordonDirector, 10% Owner	1,368,966	—	—	1,368,966	—	plan?
Nov 20, 2017 PForm 4 →	Nov 20, 5:28 pm EST	Polaris Venture Management Co. V, L.L.C. +510% Owner	500,000	$10.00	$5,000,000	18,031	—	plan?
Nov 20, 2017 CForm 4 →	Nov 20, 5:28 pm EST	Polaris Venture Management Co. V, L.L.C. +510% Owner	1,368,957	—	—	13,206	—	plan?
Nov 20, 2017 PForm 4 →	Nov 20, 5:28 pm EST	Michael Jay RossDirector, 10% Owner	500,000	$10.00	$5,000,000	1,868,961	+36.5%	plan?
Nov 20, 2017 CForm 4 →	Nov 20, 5:28 pm EST	Michael Jay RossDirector, 10% Owner	1,368,961	—	—	1,368,961	—	plan?
Nov 15, 2017 CForm 4 →	Nov 20, 10:01 am EST	Alexandria Venture Investments, LLC10% Owner	225,680	—	—	225,680	—	plan? late

Reported at this company — derivatives (options, RSUs, warrants)

Trade	Reported (ET)	Insider	Shares	Avg price	Total	Owned after	Δ stake	Flags
Jul 1, 2026 AForm 4 →	Jul 1, 4:20 pm EDT	Kelly GoldDirector	110,000	—	—	110,000	—
Mar 13, 2019 AForm 4 →	Mar 14, 9:31 pm EDT	Michael S WyzgaDirector	70,324	—	—	70,324	—
Jun 5, 2018 AForm 4 →	Jun 7, 5:07 pm EDT	Terrance McGuireDirector	10,000	—	—	10,000	—
Jun 5, 2018 AForm 4 →	Jun 7, 4:24 pm EDT	Amy W SchulmanDirector	10,000	—	—	10,000	—
Jun 5, 2018 AForm 4 →	Jun 7, 4:23 pm EDT	Michael Jay RossDirector	10,000	—	—	10,000	—
Jun 5, 2018 AForm 4 →	Jun 7, 4:23 pm EDT	Claudio NessiDirector	10,000	—	—	10,000	—
Jun 5, 2018 AForm 4 →	Jun 7, 4:22 pm EDT	David W J McGirrDirector	10,000	—	—	10,000	—
Jun 5, 2018 AForm 4 →	Jun 7, 4:21 pm EDT	Carl L GordonDirector	10,000	—	—	10,000	—
Jun 5, 2018 AForm 4 →	Jun 7, 4:19 pm EDT	Tillman U. GerngrossDirector	10,000	—	—	10,000	—
Jun 5, 2018 AForm 4 →	Jun 7, 4:17 pm EDT	William D ClarkDirector	10,000	—	—	10,000	—
Mar 7, 2018 AForm 4 →	Mar 9, 4:39 pm EST	Michael GrayCOO and CFO	110,000	—	—	110,000	—
Mar 7, 2018 AForm 4 →	Mar 9, 4:37 pm EST	David MantusChief Development Officer	50,000	—	—	50,000	—
Mar 7, 2018 AForm 4 →	Mar 9, 4:36 pm EST	Eszter NagyChief Scientific Officer	45,000	—	—	45,000	—
Mar 7, 2018 AForm 4 →	Mar 9, 4:35 pm EST	Rene RussoPresident and CEO, Director	160,000	—	—	160,000	—
Mar 7, 2018 AForm 4 →	Mar 9, 4:32 pm EST	Anthony Chris StevensChief Medical Officer	50,000	—	—	50,000	—
Nov 20, 2017 CForm 4 →	Nov 20, 9:56 pm EST	EMBL Technology Fund II GmbH & Co. KG +410% Owner	1,050,866	—	—	0	—
Nov 20, 2017 CForm 4 →	Nov 20, 7:09 pm EST	Bill & Melinda Gates Foundation10% Owner	2,464,799	—	—	0	—
Nov 20, 2017 CForm 4 →	Nov 20, 6:15 pm EST	NeoMed Innovation V L.P. +210% Owner	1,589,024	—	—	0	—
Nov 20, 2017 CForm 4 →	Nov 20, 5:43 pm EST	GV 2016 GP, L.L.C. +310% Owner	1,540,499	—	—	0	—
Nov 20, 2017 CForm 4 →	Nov 20, 5:43 pm EST	Claudio NessiDirector	1,589,024	—	—	0	—
Nov 20, 2017 CForm 4 →	Nov 20, 5:42 pm EST	Anna-Maria & Stephen Kellen Foundation, Inc.10% Owner	388,206	—	—	0	—
Nov 20, 2017 CForm 4 →	Nov 20, 5:38 pm EST	Section 32 Fund 1, LP +210% Owner	1,540,500	—	—	0	—
Nov 20, 2017 CForm 4 →	Nov 20, 5:37 pm EST	SVLSF V, LLC +410% Owner	3,969,585	—	—	0	—
Nov 20, 2017 CForm 4 →	Nov 20, 5:36 pm EST	Terrance McGuireDirector, 10% Owner	3,969,854	—	—	0	—
Nov 20, 2017 CForm 4 →	Nov 20, 5:32 pm EST	Tillman U. GerngrossDirector	308,099	—	—	0	—
Nov 20, 2017 CForm 4 →	Nov 20, 5:32 pm EST	ORBIMED ADVISORS LLC +210% Owner	3,969,587	—	—	0	—
Nov 20, 2017 CForm 4 →	Nov 20, 5:31 pm EST	Carl L GordonDirector, 10% Owner	3,969,587	—	—	0	—
Nov 20, 2017 CForm 4 →	Nov 20, 5:28 pm EST	Polaris Venture Management Co. V, L.L.C. +510% Owner	3,969,854	—	—	0	—
Nov 20, 2017 CForm 4 →	Nov 20, 5:28 pm EST	Michael Jay RossDirector, 10% Owner	3,969,585	—	—	0	—
Nov 15, 2017 AForm 4/A →	Mar 8, 2018, 9:20 pm EST	Terrance McGuireDirector	25,000	—	—	25,000	—
Nov 15, 2017 AForm 4/A →	Mar 5, 2018, 5:03 pm EST	Michael Jay RossDirector	25,000	—	—	25,000	—
Nov 15, 2017 AForm 4/A →	Mar 5, 2018, 5:03 pm EST	Amy W SchulmanDirector	25,000	—	—	25,000	—
Nov 15, 2017 AForm 4/A →	Mar 5, 2018, 5:01 pm EST	Claudio NessiDirector	25,000	—	—	25,000	—
Nov 15, 2017 AForm 4/A →	Mar 5, 2018, 4:59 pm EST	David W J McGirrDirector	25,000	—	—	25,000	—
Nov 15, 2017 AForm 4/A →	Mar 5, 2018, 4:59 pm EST	Tillman U. GerngrossDirector	25,000	—	—	25,000	—
Nov 15, 2017 AForm 4/A →	Mar 5, 2018, 4:57 pm EST	Carl L GordonDirector	25,000	—	—	25,000	—
Nov 15, 2017 AForm 4/A →	Mar 5, 2018, 4:49 pm EST	William D ClarkDirector	25,000	—	—	25,000	—
Nov 15, 2017 AForm 4 →	Dec 1, 5:26 pm EST	William D ClarkDirector	7,324	—	—	7,324	—	late amended
Nov 15, 2017 AForm 4 →	Dec 1, 5:24 pm EST	Tillman U. GerngrossDirector	7,324	—	—	7,324	—	late amended
Nov 15, 2017 AForm 4 →	Dec 1, 5:22 pm EST	Carl L GordonDirector, 10% Owner	7,324	—	—	7,324	—	late amended
Nov 15, 2017 AForm 4 →	Dec 1, 5:22 pm EST	Terrance McGuireDirector, 10% Owner	7,324	—	—	7,324	—	late amended
Nov 15, 2017 AForm 4 →	Dec 1, 5:19 pm EST	Michael Jay RossDirector, 10% Owner	7,324	—	—	7,324	—	late amended
Nov 15, 2017 AForm 4 →	Dec 1, 5:19 pm EST	Claudio NessiDirector	7,324	—	—	7,324	—	late amended
Nov 15, 2017 AForm 4 →	Dec 1, 5:18 pm EST	Amy W SchulmanDirector	7,324	—	—	7,324	—	late amended
Nov 15, 2017 AForm 4 →	Dec 1, 5:15 pm EST	David W J McGirrDirector	7,324	—	—	7,324	—	late amended
Nov 15, 2017 CForm 4 →	Nov 20, 10:01 am EST	Alexandria Venture Investments, LLC10% Owner	770,249	—	—	0	—	late