Company · CIK 0001117480 · SIC 2834 — Pharmaceutical Preparations

CHIMERIX INC · CMRX

Insider activity reported against this company. All insider holders · On EDGAR ↗

Period1M 3M 6M 1Y 2Y All datashares as filed — not split-adjusted

Open-market buys & salesbuys $1.8M · 12sales $3.6M · 20net −$1.8M

Reported at this company — common stock

Trade	Reported (ET)	Insider	Shares	Avg price	Total	Owned after	Δ stake	Flags
Feb 5, 2019 AForm 4 →	Feb 7, 7:12 pm EST	Timothy W. TrostSVP, CFO & Secretary	100,000	—	—	214,530	—	plan?
Feb 5, 2019 AForm 4 →	Feb 7, 7:11 pm EST	Garrett NicholsChief Medical Officer	100,000	—	—	312,376	—	plan?
Feb 5, 2019 AForm 4 →	Feb 7, 7:10 pm EST	Michael Albert AlrutzPrincipal Executive Officer	100,000	—	—	156,645	—	plan?
Jan 29, 2019 FForm 4 →	Jan 30, 3:20 pm EST	Garrett NicholsChief Medical Officer	3,095	$2.20	$6,821	212,376	—	plan?
Jan 29, 2019 FForm 4 →	Jan 30, 3:18 pm EST	Timothy W. TrostSVP, CFO & Secretary	2,588	$2.20	$5,694	114,530	—	plan?
Jan 23, 2019 AForm 4 →	Jan 25, 4:41 pm EST	Garrett NicholsChief Medical Officer	125,000	—	—	215,471	—	plan?
Jun 12, 2018 PForm 4 →	Jun 14, 11:52 am EDT	M Michelle BerreyPresident and CEO, Director	10,000	$4.50	$45,015	99,685	+11.2%	plan?
May 17, 2018 SForm 4 →	May 21, 1:34 pm EDT	Ernest MarioDirector	45,000	$4.80	$216,074	108,167	−29.4%	plan?
May 16, 2018 SForm 4 →	May 17, 11:51 am EDT	Ernest MarioDirector	30,000	$4.79	$143,808	153,167	−16.4%	plan?
May 15, 2018 SForm 4 →	May 16, 2:46 pm EDT	Ernest MarioDirector	30,000	$4.69	$140,808	183,167	−14.1%	plan?
May 14, 2018 FForm 4 →	May 15, 1:44 pm EDT	Garrett NicholsChief Medical Officer	5,680	$4.66	$26,490	90,471	—	plan?
May 14, 2018 FForm 4 →	May 15, 1:42 pm EDT	Linda M RichardsonChief Commercial Officer	4,545	$4.66	$21,199	54,161	—	plan?
May 11, 2018 SForm 4 →	May 15, 3:41 pm EDT	Ernest MarioDirector	52,553	$4.64	$243,613	213,167	−19.8%	plan?
May 10, 2018 SForm 4 →	May 11, 5:25 pm EDT	Ernest MarioDirector	2,815	$4.60	$12,949	265,720	−1.05%	plan?
May 9, 2018 MForm 4 →	May 10, 3:20 pm EDT	Martha J DemskiDirector	4,225	$1.57	$6,633	19,013	—	plan?
May 8, 2018 MForm 4 →	May 10, 5:34 pm EDT	M Michelle BerreyPresident and CEO, Director	11,250	$4.26	$47,925	325,256	—	plan?
Mar 6, 2018 MForm 4 →	Mar 8, 4:53 pm EST	M Michelle BerreyPresident and CEO, Director	10,071	$4.26	$42,902	311,336	—	plan?
Feb 2, 2018 FForm 4 →	Feb 5, 7:44 pm EST	Linda M RichardsonChief Commercial Officer	2,290	$4.67	$10,691	58,706	—	plan?
Feb 2, 2018 FForm 4 →	Feb 5, 7:42 pm EST	Garrett NicholsChief Medical Officer	2,330	$4.67	$10,872	96,151	—	plan?
Dec 1, 2017 SForm 4 →	Dec 5, 2:08 pm EST	Linda M RichardsonChief Commercial Officer	19,833	$4.47	$88,673	60,996	−24.5%	plan?
Jun 21, 2017 MForm 4 →	Jun 22, 4:21 pm EDT	M Michelle BerreyPresident and CEO, Director	23,474	$4.26	$99,999	323,947	—	plan?
May 12, 2017 FForm 4 →	May 16, 5:46 pm EDT	Garrett NicholsChief Medical Officer	12,712	$4.68	$59,464	98,481	—	plan?
May 12, 2017 FForm 4 →	May 16, 5:45 pm EDT	Linda M RichardsonChief Commercial Officer	10,167	$4.68	$47,577	80,829	—	plan?
Mar 10, 2017 AForm 4 →	Mar 31, 4:55 pm EDT	Timothy W. TrostSVP, CFO & Secretary	5,186	$4.10	$21,247	111,931	—	plan? late
Mar 10, 2017 AForm 4 →	Mar 31, 4:53 pm EDT	Garrett NicholsChief Medical Officer	587	$4.10	$2,405	111,193	—	plan? late
Mar 10, 2017 AForm 4 →	Mar 31, 4:52 pm EDT	M Michelle BerreyPresident and CEO, Director	4,523	$4.10	$18,531	366,684	—	plan? late
Jan 24, 2017 AForm 4 →	Jan 26, 5:57 pm EST	Timothy W. TrostSVP, CFO & Secretary	25,375	—	—	106,745	—	plan?
Jan 24, 2017 AForm 4 →	Jan 26, 5:56 pm EST	Garrett NicholsChief Medical Officer	30,375	—	—	110,606	—	plan?
Jan 24, 2017 AForm 4 →	Jan 26, 5:47 pm EST	M Michelle BerreyPresident and CEO, Director	74,000	—	—	362,161	—	plan?
Jan 24, 2017 AForm 4 →	Jan 26, 5:46 pm EST	Linda M RichardsonChief Commercial Officer	30,375	—	—	90,996	—	plan?
Dec 27, 2016 SForm 4 →	Dec 29, 4:03 pm EST	Ernest MarioDirector	100,000	$4.64	$464,367	268,535	−27.1%	plan?
Nov 29, 2016 MForm 4 →	Dec 1, 4:17 pm EST	M Michelle BerreyPresident and CEO, Director	2,400	$4.26	$10,224	288,161	—	plan?
Sep 15, 2016 SForm 4 →	Sep 16, 6:46 pm EDT	John M. LeonardDirector	5,000	$5.03	$25,163	0	−100%	plan?
Sep 9, 2016 AForm 4 →	Sep 19, 5:22 pm EDT	Timothy W. TrostSVP, CFO & Secretary	4,638	$4.05	$18,784	81,370	—	plan? late
Sep 9, 2016 AForm 4 →	Sep 19, 5:19 pm EDT	Garrett NicholsChief Medical Officer	3,566	$4.05	$14,442	80,231	—	plan? late
Sep 9, 2016 AForm 4 →	Sep 19, 5:17 pm EDT	M Michelle BerreyPresident and CEO, Director	4,523	$4.05	$18,318	285,761	—	plan? late
Aug 29, 2016 PForm 4 →	Aug 31, 3:01 pm EDT	M Michelle BerreyPresident and CEO, Director	22,417	$4.47	$100,226	281,238	+8.66%	plan?
Jun 24, 2016 PForm 4 →	Jun 28, 3:17 pm EDT	Ernest MarioDirector	50,000	$3.70	$184,845	381,440	+15.1%	plan?
Jun 24, 2016 PForm 4 →	Jun 28, 3:16 pm EDT	M Michelle BerreyPresident and CEO, Director	13,188	$3.69	$48,624	258,821	+5.37%	plan?
May 13, 2016 PForm 4 →	May 16, 1:56 pm EDT	Ernest MarioDirector	10,000	$4.53	$45,328	331,440	+3.11%	plan?
May 10, 2016 PForm 4 →	May 11, 5:15 pm EDT	Ernest MarioDirector	25,000	$4.85	$121,169	321,440	+8.43%	plan?
May 9, 2016 AForm 4 →	May 11, 5:14 pm EDT	Linda M RichardsonChief Commerical Officer	60,000	—	—	60,621	—	plan?
May 9, 2016 AForm 4 →	May 11, 5:12 pm EDT	Garrett NicholsChief Medical Officer	75,000	—	—	76,665	—	plan?
May 9, 2016 AForm 4 →	May 11, 5:11 pm EDT	Timothy W. TrostSVP, CFO & Secretary	60,000	—	—	76,732	—	plan?
May 9, 2016 AForm 4 →	May 11, 5:09 pm EDT	M Michelle BerreyPresident and CEO, Director	100,000	—	—	245,633	—	plan?
May 4, 2016 MForm 4 →	May 5, 5:05 pm EDT	Ernest MarioDirector	1,761	$5.05	$8,893	296,440	—	plan?
Apr 4, 2016 MForm 4 →	Apr 5, 5:56 pm EDT	Ernest MarioDirector	1,760	$5.05	$8,888	294,679	—	plan?
Mar 15, 2016 PForm 4 →	Mar 16, 5:15 pm EDT	Ernest MarioDirector	25,000	$5.06	$126,526	292,919	+9.33%	plan?
Mar 7, 2016 MForm 4 →	Mar 9, 1:59 pm EST	Ernest MarioDirector	1,761	$5.05	$8,893	267,919	—	plan?
Mar 1, 2016 MForm 4 →	Mar 3, 2:34 pm EST	M Michelle BerreyPresident and CEO, Director	11,001	$4.26	$46,864	145,633	—	plan?
Mar 1, 2016 PForm 4 →	Mar 2, 2:59 pm EST	Timothy WollaegerDirector	10,000	$4.61	$46,100	10,000	—	plan?
Mar 1, 2016 PForm 4 →	Mar 2, 2:58 pm EST	Martha J DemskiDirector	10,000	$4.89	$48,900	10,000	—	plan? amended
Feb 8, 2016 MForm 4 →	Feb 9, 2:06 pm EST	Ernest MarioDirector	1,760	$5.05	$8,888	266,158	—	plan?
Jan 13, 2016 MForm 4 →	Jan 14, 1:49 pm EST	Ernest MarioDirector	1,761	$5.05	$8,893	264,398	—	plan?
Dec 29, 2015 PForm 4 →	Dec 30, 2:33 pm EST	Clarence Patrick MachadoDirector	10,000	$7.08	$70,846	10,000	—	plan?
Dec 29, 2015 PForm 4 →	Dec 30, 2:32 pm EST	Ernest MarioDirector	125,000	$7.09	$886,613	262,637	+90.8%	plan?
Dec 9, 2015 MForm 4 →	Dec 11, 1:45 pm EST	Ernest MarioDirector	1,760	$5.05	$8,888	137,637	—	plan?
Nov 6, 2015 MForm 4 →	Nov 10, 4:07 pm EST	Ernest MarioDirector	1,761	$5.05	$8,893	135,877	—	plan?
Nov 2, 2015 SForm 4 →	Nov 3, 5:41 pm EST	Martha J DemskiDirector	1,126	$41.35	$46,561	0	−100%	plan?
Nov 2, 2015 MForm 4 →	Nov 3, 5:41 pm EST	Martha J DemskiDirector	1,126	$1.53	$1,723	1,126	—	plan?
Oct 6, 2015 MForm 4 →	Oct 7, 3:07 pm EDT	Ernest MarioDirector	1,761	$5.05	$8,893	134,116	—	plan?
Oct 1, 2015 SForm 4 →	Oct 2, 2:43 pm EDT	Martha J DemskiDirector	2,000	$37.68	$75,368	0	−100%	plan?
Oct 1, 2015 MForm 4 →	Oct 2, 2:43 pm EDT	Martha J DemskiDirector	2,000	$1.53	$3,060	2,000	—	plan?
Sep 4, 2015 MForm 4 →	Sep 8, 1:30 pm EDT	Ernest MarioDirector	2,592	$17.92	$46,453	132,355	—	plan?
Sep 1, 2015 SForm 4 →	Sep 3, 11:50 am EDT	Martha J DemskiDirector	2,000	$48.18	$96,366	0	−100%	plan?
Sep 1, 2015 MForm 4 →	Sep 3, 11:50 am EDT	Martha J DemskiDirector	2,000	$1.53	$3,060	2,000	—	plan?
Aug 26, 2015 MForm 4 →	Aug 27, 4:16 pm EDT	M Michelle BerreyPresident and CEO, Director	2,796	$18.75	$52,425	133,434	—	plan?
Aug 21, 2015 PForm 4 →	Aug 25, 2:25 pm EDT	John M. LeonardDirector	1,000	$47.38	$47,380	1,000	—	plan?
Aug 12, 2015 MForm 4 →	Aug 13, 2:56 pm EDT	Timothy W. TrostSVP, CFO & Secretary	5,333	$18.75	$99,994	15,183	—	plan?
Aug 6, 2015 MForm 4 →	Aug 7, 2:49 pm EDT	Ernest MarioDirector	5,232	$14.49	$75,791	129,763	—	plan?
Aug 3, 2015 SForm 4 →	Aug 5, 4:52 pm EDT	Martha J DemskiDirector	2,000	$54.61	$109,228	0	−100%	plan?
Aug 3, 2015 MForm 4 →	Aug 5, 4:52 pm EDT	Martha J DemskiDirector	2,000	$1.53	$3,060	2,000	—	plan?
Jul 17, 2015 SForm 4 →	Jul 20, 5:02 pm EDT	Timothy W. TrostSVP, CFO & Secretary	28,000	$50.00	$1,400,000	9,850	−74.0%	plan?
Jul 17, 2015 MForm 4 →	Jul 20, 5:02 pm EDT	Timothy W. TrostSVP, CFO & Secretary	28,000	$2.35	$65,800	37,850	—	plan?
Jul 1, 2015 SForm 4 →	Jul 2, 4:42 pm EDT	Martha J DemskiDirector	2,000	$46.03	$92,051	0	−100%	plan?
Jul 1, 2015 MForm 4 →	Jul 2, 4:42 pm EDT	Martha J DemskiDirector	2,000	$1.53	$3,060	2,000	—	plan?
Jun 10, 2015 MForm 4 →	Jun 11, 2:31 pm EDT	Ernest MarioDirector	5,279	$11.11	$58,672	124,531	—	plan?
Jun 1, 2015 SForm 4 →	Jun 3, 2:49 pm EDT	Martha J DemskiDirector	2,000	$41.58	$83,164	0	−100%	plan?
Jun 1, 2015 MForm 4 →	Jun 3, 2:49 pm EDT	Martha J DemskiDirector	2,000	$1.53	$3,060	2,000	—	plan?
May 12, 2015 PForm 4 →	May 14, 12:46 pm EDT	Lisa RicciardiDirector	1,950	$38.54	$75,153	1,950	—	plan?
May 1, 2015 SForm 4 →	May 4, 5:04 pm EDT	Martha J DemskiDirector	2,000	$34.71	$69,420	0	−100%	plan?
May 1, 2015 MForm 4 →	May 4, 5:04 pm EDT	Martha J DemskiDirector	2,000	$1.53	$3,060	2,000	—	plan?
Apr 6, 2015 MForm 4 →	Apr 7, 4:08 pm EDT	Ernest MarioDirector	2,641	$11.12	$29,362	119,252	—	plan?
Apr 1, 2015 SForm 4 →	Apr 3, 1:09 pm EDT	Martha J DemskiDirector	2,000	$36.88	$73,752	0	−100%	plan?
Apr 1, 2015 MForm 4 →	Apr 3, 1:09 pm EDT	Martha J DemskiDirector	2,000	$1.53	$3,060	2,000	—	plan?
Mar 23, 2015 MForm 4 →	Mar 25, 3:02 pm EDT	Michael D. RogersChief Development Officer	6,372	$7.57	$48,236	21,630	—	plan?
Mar 20, 2015 MForm 4 →	Mar 24, 2:25 pm EDT	M Michelle BerreyPresident and CEO, Director	12,926	$10.53	$136,078	130,638	—	plan?
Mar 18, 2015 MForm 4 →	Mar 20, 2:41 pm EDT	Ernest MarioDirector	5,279	$11.11	$58,672	116,611	—	plan?
Mar 2, 2015 SForm 4 →	Mar 3, 3:41 pm EST	Martha J DemskiDirector	2,000	$40.18	$80,350	0	−100%	plan?
Mar 2, 2015 MForm 4 →	Mar 3, 3:41 pm EST	Martha J DemskiDirector	2,000	$1.53	$3,060	2,000	—	plan?
Feb 2, 2015 SForm 4 →	Feb 3, 2:36 pm EST	Martha J DemskiDirector	2,000	$38.38	$76,769	0	−100%	plan?
Feb 2, 2015 MForm 4 →	Feb 3, 2:36 pm EST	Martha J DemskiDirector	2,000	$1.53	$3,060	2,000	—	plan?
Jan 21, 2015 MForm 4 →	Jan 22, 1:18 pm EST	M Michelle BerreyPresident and CEO, Director	3,668	$4.26	$15,626	116,282	—	plan?
Jan 16, 2015 MForm 4 →	Jan 20, 5:50 pm EST	Ernest MarioDirector	5,279	$11.11	$58,672	111,332	—	plan?
Jan 2, 2015 SForm 4 →	Jan 6, 4:40 pm EST	Martha J DemskiDirector	2,000	$41.08	$82,154	0	−100%	plan?
Jan 2, 2015 MForm 4 →	Jan 6, 4:40 pm EST	Martha J DemskiDirector	2,000	$1.53	$3,060	2,000	—	plan?
Oct 3, 2014 GForm 4 →	Mar 2, 2016, 2:59 pm EST	Timothy WollaegerDirector	259	—	—	8,702	—	plan? late

Reported at this company — derivatives (options, RSUs, warrants)

Trade	Reported (ET)	Insider	Shares	Avg price	Total	Owned after	Δ stake
Jan 23, 2019 AForm 4 →	Jan 25, 4:42 pm EST	Timothy W. TrostSVP, CFO & Secretary	176,000	—	—	176,000	—
Jan 23, 2019 AForm 4 →	Jan 25, 4:41 pm EST	Garrett NicholsChief Medical Officer	200,000	—	—	200,000	—
Jan 23, 2019 AForm 4 →	Jan 25, 4:40 pm EST	M Michelle BerreyPresident and CEO, Director	400,000	—	—	400,000	—
Jun 20, 2018 AForm 4 →	Jun 21, 5:43 pm EDT	Catherine GillissDirector	21,000	—	—	21,000	—
Jun 20, 2018 AForm 4 →	Jun 21, 5:42 pm EDT	Martha J DemskiDirector	21,000	—	—	21,000	—
Jun 20, 2018 AForm 4 →	Jun 21, 5:41 pm EDT	Robert J. MeyerDirector	21,000	—	—	21,000	—
Jun 20, 2018 AForm 4 →	Jun 21, 5:40 pm EDT	Patrick MachadoDirector	21,000	—	—	21,000	—
Jun 20, 2018 AForm 4 →	Jun 21, 5:39 pm EDT	James M DalyDirector	21,000	—	—	21,000	—
Jun 20, 2018 AForm 4 →	Jun 21, 5:38 pm EDT	Ronald C Renaud Jr.Director	21,000	—	—	21,000	—
Jun 20, 2018 AForm 4 →	Jun 21, 5:37 pm EDT	Ed GreissingDirector	21,000	—	—	21,000	—
Jun 20, 2018 AForm 4 →	Jun 21, 5:35 pm EDT	Fred A MiddletonDirector	21,000	—	—	21,000	—
May 9, 2018 MForm 4 →	May 10, 3:20 pm EDT	Martha J DemskiDirector	4,225	—	—	0	—
May 8, 2018 MForm 4 →	May 10, 5:34 pm EDT	M Michelle BerreyPresident and CEO, Director	11,250	—	—	15,161	—
Mar 28, 2018 AForm 4 →	Mar 30, 6:13 pm EDT	Fred A MiddletonDirector	42,000	—	—	42,000	—
Mar 28, 2018 AForm 4 →	Mar 30, 6:12 pm EDT	Robert J. MeyerDirector	42,000	—	—	42,000	—
Mar 28, 2018 AForm 4 →	Mar 30, 6:10 pm EDT	Ed GreissingDirector	42,000	—	—	42,000	—
Mar 6, 2018 MForm 4 →	Mar 8, 4:53 pm EST	M Michelle BerreyPresident and CEO, Director	10,071	—	—	26,411	—
Jan 25, 2018 AForm 4 →	Jan 29, 3:52 pm EST	M Michelle BerreyPresident and CEO, Director	400,000	—	—	400,000	—
Jan 25, 2018 AForm 4 →	Jan 29, 3:50 pm EST	Garrett NicholsChief Medical Officer	148,500	—	—	148,500	—
Jan 25, 2018 AForm 4 →	Jan 29, 3:49 pm EST	Timothy W. TrostSVP, CFO & Secretary	141,750	—	—	141,750	—
Jan 25, 2018 AForm 4 →	Jan 29, 3:47 pm EST	Linda M RichardsonChief Commercial Officer	135,000	—	—	135,000	—
Jun 28, 2017 AForm 4 →	Jun 29, 4:22 pm EDT	James M DalyDirector	21,000	—	—	21,000	—
Jun 28, 2017 AForm 4 →	Jun 29, 4:21 pm EDT	Martha J DemskiDirector	21,000	—	—	21,000	—
Jun 28, 2017 AForm 4 →	Jun 29, 4:20 pm EDT	Catherine GillissDirector	21,000	—	—	21,000	—
Jun 28, 2017 AForm 4 →	Jun 29, 4:19 pm EDT	John M. LeonardDirector	21,000	—	—	21,000	—
Jun 28, 2017 AForm 4 →	Jun 29, 4:19 pm EDT	Patrick MachadoDirector	21,000	—	—	21,000	—
Jun 28, 2017 AForm 4 →	Jun 29, 4:18 pm EDT	Ernest MarioDirector	27,341	—	—	6,341	—
Jun 28, 2017 AForm 4 →	Jun 29, 4:16 pm EDT	James NiedelDirector	21,000	—	—	21,000	—
Jun 28, 2017 AForm 4 →	Jun 29, 4:15 pm EDT	Ronald C Renaud Jr.Director	21,000	—	—	21,000	—
Jun 21, 2017 MForm 4 →	Jun 22, 4:21 pm EDT	M Michelle BerreyPresident and CEO, Director	23,474	—	—	36,482	—
Jan 24, 2017 AForm 4 →	Jan 26, 5:57 pm EST	Timothy W. TrostSVP, CFO & Secretary	50,750	—	—	50,750	—
Jan 24, 2017 AForm 4 →	Jan 26, 5:56 pm EST	Garrett NicholsChief Medical Officer	60,750	—	—	60,750	—
Jan 24, 2017 AForm 4 →	Jan 26, 5:47 pm EST	M Michelle BerreyPresident and CEO, Director	148,000	—	—	148,000	—
Jan 24, 2017 AForm 4 →	Jan 26, 5:46 pm EST	Linda M RichardsonChief Commercial Officer	60,750	—	—	60,750	—
Nov 29, 2016 MForm 4 →	Dec 1, 4:17 pm EST	M Michelle BerreyPresident and CEO, Director	2,400	—	—	59,956	—
Jun 24, 2016 AForm 4 →	Jun 28, 3:24 pm EDT	James M DalyDirector	9,000	—	—	9,000	—
Jun 24, 2016 AForm 4 →	Jun 28, 3:22 pm EDT	Martha J DemskiDirector	9,000	—	—	9,000	—
Jun 24, 2016 AForm 4 →	Jun 28, 3:21 pm EDT	Catherine GillissDirector	9,000	—	—	9,000	—
Jun 24, 2016 AForm 4 →	Jun 28, 3:21 pm EDT	John M. LeonardDirector	9,000	—	—	9,000	—
Jun 24, 2016 AForm 4 →	Jun 28, 3:20 pm EDT	James NiedelDirector	9,000	—	—	9,000	—
Jun 24, 2016 AForm 4 →	Jun 28, 3:19 pm EDT	Lisa RicciardiDirector	9,000	—	—	9,000	—
Jun 24, 2016 AForm 4 →	Jun 28, 3:18 pm EDT	Ronald C Renaud Jr.Director	9,000	—	—	9,000	—
Jun 24, 2016 AForm 4 →	Jun 28, 3:17 pm EDT	Ernest MarioDirector	18,634	—	—	9,634	—
Jun 24, 2016 AForm 4 →	Jun 28, 3:16 pm EDT	Clarence Patrick MachadoDirector	9,000	—	—	9,000	—
May 4, 2016 MForm 4 →	May 5, 5:05 pm EDT	Ernest MarioDirector	1,761	—	—	15,845	—
Apr 4, 2016 MForm 4 →	Apr 5, 5:56 pm EDT	Ernest MarioDirector	1,760	—	—	17,606	—
Mar 7, 2016 MForm 4 →	Mar 9, 1:59 pm EST	Ernest MarioDirector	1,761	—	—	19,366	—
Mar 1, 2016 MForm 4 →	Mar 3, 2:34 pm EST	M Michelle BerreyPresident and CEO, Director	11,001	—	—	62,356	—
Feb 8, 2016 MForm 4 →	Feb 9, 2:06 pm EST	Ernest MarioDirector	1,760	—	—	21,127	—
Jan 13, 2016 MForm 4 →	Jan 14, 1:49 pm EST	Ernest MarioDirector	1,761	—	—	22,887	—
Jan 8, 2016 AForm 4 →	Jan 12, 8:10 pm EST	M Michelle BerreyPresident and CEO, Director	483,600	—	—	483,600	—
Jan 8, 2016 AForm 4 →	Jan 12, 8:09 pm EST	Timothy W. TrostSVP, CFO & Secretary	178,000	—	—	178,000	—
Jan 8, 2016 AForm 4 →	Jan 12, 8:08 pm EST	Michael D. RogersChief Development Officer	178,000	—	—	178,000	—
Jan 8, 2016 AForm 4 →	Jan 12, 8:06 pm EST	Garrett NicholsChief Medical Officer	178,000	—	—	178,000	—
Jan 8, 2016 AForm 4 →	Jan 12, 8:05 pm EST	Linda M RichardsonChief Commerical Officer	178,000	—	—	178,000	—
Dec 9, 2015 MForm 4 →	Dec 11, 1:45 pm EST	Ernest MarioDirector	1,760	—	—	24,648	—
Nov 6, 2015 MForm 4 →	Nov 10, 4:07 pm EST	Ernest MarioDirector	1,761	—	—	26,408	—
Nov 2, 2015 MForm 4 →	Nov 3, 5:41 pm EST	Martha J DemskiDirector	1,126	—	—	0	—
Oct 6, 2015 MForm 4 →	Oct 7, 3:07 pm EDT	Ernest MarioDirector	1,761	—	—	28,169	—
Oct 1, 2015 MForm 4 →	Oct 2, 2:43 pm EDT	Martha J DemskiDirector	2,000	—	—	1,126	—
Sep 4, 2015 MForm 4 →	Sep 8, 1:30 pm EDT	Ernest MarioDirector	2,592	—	—	8,319	—
Sep 1, 2015 MForm 4 →	Sep 3, 11:50 am EDT	Martha J DemskiDirector	2,000	—	—	3,126	—
Aug 26, 2015 MForm 4 →	Aug 27, 4:16 pm EDT	M Michelle BerreyPresident and CEO, Director	2,796	—	—	58,713	—
Aug 12, 2015 MForm 4 →	Aug 13, 2:56 pm EDT	Timothy W. TrostSVP, CFO & Secretary	5,333	—	—	44,734	—
Aug 6, 2015 MForm 4 →	Aug 7, 2:49 pm EDT	Ernest MarioDirector	5,232	—	—	9,151	—
Aug 3, 2015 MForm 4 →	Aug 5, 4:52 pm EDT	Martha J DemskiDirector	2,000	—	—	5,126	—
Jul 17, 2015 MForm 4 →	Jul 20, 5:02 pm EDT	Timothy W. TrostSVP, CFO & Secretary	28,000	—	—	78,461	—
Jul 1, 2015 MForm 4 →	Jul 2, 4:42 pm EDT	Martha J DemskiDirector	2,000	—	—	7,126	—
Jun 22, 2015 AForm 4 →	Jun 24, 6:29 pm EDT	Timothy WollaegerDirector	9,000	—	—	9,000	—
Jun 22, 2015 AForm 4 →	Jun 24, 6:27 pm EDT	Lisa RicciardiDirector	9,000	—	—	9,000	—
Jun 22, 2015 AForm 4 →	Jun 24, 6:25 pm EDT	Ronald C Renaud Jr.Director	9,000	—	—	9,000	—
Jun 22, 2015 AForm 4 →	Jun 24, 6:24 pm EDT	James NiedelDirector	9,000	—	—	9,000	—
Jun 22, 2015 AForm 4 →	Jun 24, 6:22 pm EDT	Ernest MarioDirector	9,983	—	—	9,983	—
Jun 22, 2015 AForm 4 →	Jun 24, 6:19 pm EDT	Clarence Patrick MachadoDirector	9,000	—	—	9,000	—
Jun 22, 2015 AForm 4 →	Jun 24, 6:17 pm EDT	John M. LeonardDirector	9,000	—	—	9,000	—
Jun 22, 2015 AForm 4 →	Jun 24, 6:16 pm EDT	Catherine GillissDirector	9,000	—	—	9,000	—
Jun 22, 2015 AForm 4 →	Jun 24, 6:13 pm EDT	Martha J DemskiDirector	9,000	—	—	9,000	—
Jun 22, 2015 AForm 4 →	Jun 24, 6:12 pm EDT	James M DalyDirector	9,000	—	—	9,000	—
Jun 10, 2015 MForm 4 →	Jun 11, 2:31 pm EDT	Ernest MarioDirector	5,279	—	—	129	—
Jun 1, 2015 MForm 4 →	Jun 3, 2:49 pm EDT	Martha J DemskiDirector	2,000	—	—	9,126	—
May 1, 2015 MForm 4 →	May 4, 5:04 pm EDT	Martha J DemskiDirector	2,000	—	—	11,126	—
Apr 6, 2015 MForm 4 →	Apr 7, 4:08 pm EDT	Ernest MarioDirector	2,641	—	—	387	—
Apr 1, 2015 MForm 4 →	Apr 3, 1:09 pm EDT	Martha J DemskiDirector	2,000	—	—	13,126	—
Mar 23, 2015 MForm 4 →	Mar 25, 3:02 pm EDT	Michael D. RogersChief Development Officer	6,372	—	—	79,219	—
Mar 20, 2015 MForm 4 →	Mar 24, 2:25 pm EDT	M Michelle BerreyPresident and CEO, Director	12,926	—	—	61,509	—
Mar 18, 2015 MForm 4 →	Mar 20, 2:41 pm EDT	Ernest MarioDirector	5,279	—	—	517	—
Mar 2, 2015 MForm 4 →	Mar 3, 3:41 pm EST	Martha J DemskiDirector	2,000	—	—	15,126	—
Feb 2, 2015 MForm 4 →	Feb 3, 2:36 pm EST	Martha J DemskiDirector	2,000	—	—	17,126	—
Jan 28, 2015 AForm 4 →	Jan 30, 3:53 pm EST	Timothy W. TrostSr. Vice President and CFO	65,000	—	—	65,000	—
Jan 28, 2015 AForm 4 →	Jan 30, 3:50 pm EST	Michael D. RogersChief Development Officer	65,000	—	—	65,000	—
Jan 28, 2015 AForm 4 →	Jan 30, 3:49 pm EST	Linda M RichardsonChief Commercial Officer	65,000	—	—	65,000	—
Jan 28, 2015 AForm 4 →	Jan 30, 3:45 pm EST	M Michelle BerreyPresident and CEO, Director	184,200	—	—	184,200	—
Jan 28, 2015 AForm 4 →	Jan 30, 3:42 pm EST	Garrett NicholsChief Medical Officer	22,000	—	—	22,000	—
Jan 21, 2015 MForm 4 →	Jan 22, 1:18 pm EST	M Michelle BerreyPresident and CEO, Director	3,668	—	—	80,692	—
Jan 16, 2015 MForm 4 →	Jan 20, 5:50 pm EST	Ernest MarioDirector	5,279	—	—	775	—
Jan 2, 2015 MForm 4 →	Jan 6, 4:40 pm EST	Martha J DemskiDirector	2,000	—	—	19,126	—
Aug 25, 2014 MForm 4/A →	Jul 23, 2015, 6:18 pm EDT	Timothy W. TrostSVP, CFO & Secretary	5,000	—	—	111,461	—