Company · CIK 0001060736 · SIC 2836 — Biological Products, (No Diagnostic Substances)
SEATTLE GENETICS INC /WA · SGEN
Insider activity reported against this company. All insider holders · On EDGAR ↗
Reported at this company — common stock
| Trade | Reported (ET) | Insider | Shares | Avg price | Total | Owned after | Δ stake | Flags |
|---|---|---|---|---|---|---|---|---|
| Mar 8, 2019 SForm 4 → | Mar 12, 7:34 pm EDT | Clay B SiegallPresident and CEO, Director | 20,148 | $69.19 | $1,394,094 | 732,613 | −2.68% | plan? |
| Mar 8, 2019 MForm 4 → | Mar 12, 7:34 pm EDT | Clay B SiegallPresident and CEO, Director | 20,148 | $12.16 | $245,000 | 740,115 | — | plan? |
| Mar 8, 2019 SForm 4 → | Mar 12, 7:31 pm EDT | Vaughn B HimesChief Technical Officer | 8,000 | $68.72 | $549,746 | 177,329 | −4.32% | plan? |
| Mar 8, 2019 MForm 4 → | Mar 12, 7:31 pm EDT | Vaughn B HimesChief Technical Officer | 8,000 | $12.00 | $96,000 | 185,329 | — | plan? |
| Mar 4, 2019 SForm 4 → | Mar 6, 6:58 pm EST | Todd E SimpsonChief Financial Officer | 10,000 | $75.00 | $750,000 | 184,280 | −5.15% | plan? |
| Feb 15, 2019 AForm 4 → | Feb 20, 4:39 pm EST | Roger D DanseySee Remarks | 5,768 | — | — | 83,009 | — | plan? |
| Feb 8, 2019 SForm 4 → | Feb 12, 6:25 pm EST | Clay B SiegallSee Remarks, Director | 20,148 | $65.17 | $1,313,126 | 732,613 | −2.68% | plan? |
| Feb 8, 2019 MForm 4 → | Feb 12, 6:25 pm EST | Clay B SiegallSee Remarks, Director | 20,148 | $12.16 | $245,000 | 740,690 | — | plan? |
| Jan 8, 2019 SForm 4 → | Jan 10, 9:09 pm EST | David W GryskaDirector | 5,000 | $65.04 | $325,200 | 45,050 | −9.99% | plan? |
| Jan 8, 2019 MForm 4 → | Jan 10, 9:09 pm EST | David W GryskaDirector | 5,000 | $12.76 | $63,800 | 50,050 | — | plan? |
| Jan 8, 2019 SForm 4 → | Jan 10, 8:27 pm EST | Clay B SiegallPresident and CEO, Director | 20,148 | $65.73 | $1,324,237 | 732,613 | −2.68% | plan? |
| Jan 8, 2019 MForm 4 → | Jan 10, 8:27 pm EST | Clay B SiegallPresident and CEO, Director | 20,148 | $12.16 | $245,000 | 735,613 | — | plan? |
| Dec 10, 2018 SForm 4 → | Dec 12, 7:31 pm EST | Clay B SiegallPresident and CEO, Director | 20,148 | $59.74 | $1,203,545 | 732,613 | −2.68% | plan? |
| Dec 10, 2018 MForm 4 → | Dec 12, 7:31 pm EST | Clay B SiegallPresident and CEO, Director | 20,148 | $12.16 | $245,000 | 733,313 | — | plan? |
| Nov 30, 2018 MForm 4 → | Dec 4, 7:37 pm EST | Vaughn B HimesChief Technical Officer | 5,000 | $12.00 | $60,000 | 177,329 | — | plan? |
| Nov 30, 2018 SForm 4 → | Dec 4, 7:37 pm EST | Vaughn B HimesChief Technical Officer | 5,000 | $62.14 | $310,718 | 172,329 | −2.82% | plan? |
| Nov 29, 2018 SForm 4 → | Nov 30, 6:32 pm EST | Darren S ClineEVP, Commercial | 7,000 | $62.88 | $440,160 | 72,556 | −8.80% | plan? |
| Nov 21, 2018 SForm 4 → | Nov 21, 6:42 pm EST | Darren S ClineEVP, Commercial | 4,167 | $56.68 | $236,204 | 79,556 | −4.98% | plan? |
| Nov 8, 2018 SForm 4 → | Nov 9, 5:54 pm EST | Clay B SiegallPresident and CEO, Director | 20,148 | $61.54 | $1,239,873 | 732,613 | −2.68% | plan? |
| Nov 8, 2018 MForm 4 → | Nov 9, 5:54 pm EST | Clay B SiegallPresident and CEO, Director | 20,148 | $12.16 | $245,000 | 746,091 | — | plan? |
| Oct 30, 2018 MForm 4 → | Nov 1, 5:55 pm EDT | Srinivas AkkarajuDirector | 5,000 | $8.38 | $41,900 | 37,205 | — | plan? |
| Oct 8, 2018 SForm 4 → | Oct 9, 8:13 pm EDT | Clay B SiegallPresident and CEO, Director | 20,148 | $77.39 | $1,559,231 | 732,613 | −2.68% | plan? |
| Oct 8, 2018 MForm 4 → | Oct 9, 8:13 pm EDT | Clay B SiegallPresident and CEO, Director | 20,148 | $12.16 | $245,000 | 738,824 | — | plan? |
| Sep 17, 2018 SForm 4 → | Sep 19, 6:36 pm EDT | Clay B SiegallPresident and CEO, Director | 20,148 | $76.84 | $1,548,196 | 732,613 | −2.68% | plan? |
| Sep 17, 2018 MForm 4 → | Sep 19, 6:36 pm EDT | Clay B SiegallPresident and CEO, Director | 20,148 | $12.16 | $245,000 | 734,003 | — | plan? |
| Sep 7, 2018 AForm 4 → | Sep 11, 7:29 pm EDT | Roger D DanseyChief Medical Officer | 5,898 | — | — | 77,241 | — | plan? |
| Sep 7, 2018 SForm 4 → | Sep 11, 7:26 pm EDT | Vaughn B HimesChief Technical Officer | 5,000 | $76.99 | $384,962 | 177,329 | −2.74% | plan? |
| Sep 7, 2018 MForm 4 → | Sep 11, 7:26 pm EDT | Vaughn B HimesChief Technical Officer | 5,000 | $12.00 | $60,000 | 182,329 | — | plan? |
| Aug 30, 2018 AForm 4 → | Sep 4, 8:58 pm EDT | Todd E SimpsonChief Financial Officer | 20,715 | — | — | 194,280 | — | plan? |
| Aug 30, 2018 AForm 4 → | Sep 4, 8:56 pm EDT | Jean I LiuGC/EVP, Leg Affairs | 17,608 | — | — | 74,349 | — | plan? |
| Aug 30, 2018 AForm 4 → | Sep 4, 8:54 pm EDT | Vaughn B HimesChief Technical Officer | 17,953 | — | — | 177,329 | — | plan? |
| Aug 30, 2018 AForm 4 → | Sep 4, 8:49 pm EDT | Roger D DanseyChief Medical Officer | 1,343 | — | — | 71,343 | — | plan? |
| Aug 30, 2018 AForm 4 → | Sep 4, 8:41 pm EDT | Darren S ClineEVP, Commercial | 18,644 | — | — | 83,723 | — | plan? |
| Aug 30, 2018 AForm 4 → | Sep 4, 8:36 pm EDT | Clay B SiegallPresident and CEO, Director | 95,981 | — | — | 732,613 | — | plan? |
| Aug 27, 2018 SForm 4 → | Aug 29, 7:40 pm EDT | Todd E SimpsonChief Financial Officer | 5,427 | $74.23 | $402,856 | 173,565 | −3.03% | plan? |
| Aug 27, 2018 SForm 4 → | Aug 29, 7:39 pm EDT | Clay B SiegallPresident and CEO, Director | 25,514 | $74.23 | $1,893,950 | 636,632 | −3.85% | plan? |
| Aug 27, 2018 SForm 4 → | Aug 29, 7:37 pm EDT | Jean I LiuGC/EVP, Leg Affairs | 4,123 | $74.23 | $306,058 | 56,741 | −6.77% | plan? |
| Aug 27, 2018 SForm 4 → | Aug 29, 7:35 pm EDT | Vaughn B HimesChief Technical Officer | 5,530 | $74.23 | $410,502 | 159,376 | −3.35% | plan? |
| Aug 27, 2018 SForm 4 → | Aug 29, 7:32 pm EDT | Darren S ClineEVP, Commercial | 4,784 | $74.23 | $355,125 | 65,079 | −6.85% | plan? |
| Aug 21, 2018 SForm 4 → | Aug 23, 8:01 pm EDT | Clay B SiegallPresident and CEO, Director | 25,000 | $74.95 | $1,873,750 | 662,146 | −3.64% | plan? |
| Aug 9, 2018 SForm 4 → | Aug 13, 4:47 pm EDT | Clay B SiegallSee Remarks, Director | 18,831 | $72.71 | $1,369,153 | 687,146 | −2.67% | plan? |
| Aug 9, 2018 MForm 4 → | Aug 13, 4:47 pm EDT | Clay B SiegallSee Remarks, Director | 18,831 | $11.09 | $208,836 | 689,266 | — | plan? |
| Jul 31, 2018 SForm 4 → | Aug 2, 8:00 pm EDT | Marc E LippmanDirector | 7,400 | $69.25 | $512,450 | 128,350 | −5.45% | plan? |
| Jul 9, 2018 SForm 4 → | Jul 11, 8:28 pm EDT | Clay B SiegallPresident and CEO, Director | 18,832 | $69.07 | $1,300,770 | 687,146 | −2.67% | plan? |
| Jul 9, 2018 MForm 4 → | Jul 11, 8:28 pm EDT | Clay B SiegallPresident and CEO, Director | 18,832 | $11.09 | $208,847 | 690,768 | — | plan? |
| Jun 15, 2018 AForm 4 → | Jun 19, 7:57 pm EDT | Roger D DanseyChief Medical Officer | 70,000 | — | — | 70,000 | — | plan? |
| Jun 12, 2018 SForm 4 → | Jun 14, 6:31 pm EDT | Darren S ClineEVP, Commercial | 12,054 | $69.00 | $831,688 | 69,863 | −14.7% | plan? |
| Jun 12, 2018 MForm 4 → | Jun 14, 6:31 pm EDT | Darren S ClineEVP, Commercial | 10,086 | $29.14 | $293,910 | 79,831 | — | plan? |
| Jun 8, 2018 SForm 4 → | Jun 12, 7:34 pm EDT | Clay B SiegallPresident and CEO, Director | 18,832 | $65.12 | $1,226,341 | 687,146 | −2.67% | plan? |
| Jun 8, 2018 MForm 4 → | Jun 12, 7:34 pm EDT | Clay B SiegallPresident and CEO, Director | 18,832 | $11.09 | $208,847 | 705,278 | — | plan? |
| May 31, 2018 SForm 4 → | Jun 4, 7:11 pm EDT | Vaughn B HimesChief Technical Officer | 5,000 | $58.47 | $292,365 | 164,906 | −2.94% | plan? |
| May 31, 2018 MForm 4 → | Jun 4, 7:11 pm EDT | Vaughn B HimesChief Technical Officer | 5,000 | $12.00 | $60,000 | 169,906 | — | plan? |
| May 18, 2018 AForm 4 → | May 22, 8:16 pm EDT | Srinivas AkkarajuDirector | 3,700 | — | — | 32,205 | — | plan? |
| May 18, 2018 AForm 4 → | May 22, 8:13 pm EDT | Daniel G WelchDirector | 3,700 | — | — | 69,800 | — | plan? |
| May 18, 2018 AForm 4 → | May 22, 8:10 pm EDT | Nancy A SimonianDirector | 3,700 | — | — | 21,800 | — | plan? |
| May 18, 2018 AForm 4 → | May 22, 8:09 pm EDT | John A OrwinDirector | 3,700 | — | — | 21,800 | — | plan? |
| May 18, 2018 AForm 4 → | May 22, 8:07 pm EDT | Marc E LippmanDirector | 3,700 | — | — | 135,750 | — | plan? |
| May 18, 2018 AForm 4 → | May 22, 8:06 pm EDT | David W GryskaDirector | 3,700 | — | — | 45,050 | — | plan? |
| May 18, 2018 AForm 4 → | May 18, 4:25 pm EDT | BAKER BROS. ADVISORS LP +5Director, 10% Owner | 7,400 | $56.77 | $420,098 | 45,829,686 | — | plan? |
| May 9, 2018 SForm 4 → | May 11, 8:01 pm EDT | Clay B SiegallPresident and CEO, Director | 18,832 | $54.97 | $1,035,114 | 687,146 | −2.67% | plan? |
| May 9, 2018 MForm 4 → | May 11, 8:01 pm EDT | Clay B SiegallPresident and CEO, Director | 18,832 | $11.09 | $208,847 | 693,886 | — | plan? |
| May 9, 2018 SForm 4 → | May 11, 7:59 pm EDT | Darren S ClineEVP, Commercial | 9,000 | $55.33 | $497,983 | 71,831 | −11.1% | plan? |
| May 9, 2018 MForm 4 → | May 11, 7:59 pm EDT | Darren S ClineEVP, Commercial | 9,000 | $16.20 | $145,790 | 80,831 | — | plan? |
| May 4, 2018 PForm 4 → | May 8, 5:17 pm EDT | BAKER BROS. ADVISORS LP +5Director, 10% Owner | 460,651 | $53.34 | $24,570,226 | 45,825,986 | +1.02% | plan? |
| May 3, 2018 SForm 4 → | May 7, 7:08 pm EDT | Darren S ClineEVP, Commercial | 4,000 | $53.81 | $215,238 | 71,831 | −5.27% | plan? |
| May 1, 2018 MForm 4 → | May 2, 6:05 pm EDT | BAKER BROS. ADVISORS LP +5Director, 10% Owner | 20,000 | $10.08 | $201,600 | 44,988,471 | — | plan? |
| Apr 30, 2018 PForm 4 → | May 2, 6:05 pm EDT | BAKER BROS. ADVISORS LP +5Director, 10% Owner | 1,000,000 | $51.26 | $51,258,497 | 45,365,335 | +2.25% | plan? |
| Apr 9, 2018 SForm 4 → | Apr 11, 8:38 pm EDT | Clay B SiegallPresident and CEO, Director | 18,832 | $50.52 | $951,393 | 687,146 | −2.67% | plan? |
| Apr 9, 2018 MForm 4 → | Apr 11, 8:38 pm EDT | Clay B SiegallPresident and CEO, Director | 18,832 | $11.09 | $208,847 | 705,978 | — | plan? |
| Mar 20, 2018 MForm 4 → | Mar 22, 7:04 pm EDT | Jonathan G DrachmanCMO & EVP, R & D | 31,039 | $14.15 | $439,134 | 201,973 | — | plan? |
| Mar 15, 2018 SForm 4 → | Mar 19, 7:35 pm EDT | Vaughn B HimesSee Remarks | 5,000 | $58.12 | $290,604 | 164,906 | −2.94% | plan? |
| Mar 15, 2018 MForm 4 → | Mar 19, 7:35 pm EDT | Vaughn B HimesSee Remarks | 5,000 | $12.00 | $60,000 | 169,906 | — | plan? |
| Mar 15, 2018 AForm 4 → | Mar 15, 9:34 pm EDT | Alpna SethDirector | 5,750 | — | — | 5,750 | — | plan? |
| Mar 9, 2018 SForm 4 → | Mar 13, 8:43 pm EDT | Clay B SiegallPresident and CEO, Director | 18,832 | $57.32 | $1,079,436 | 687,146 | −2.67% | plan? |
| Mar 9, 2018 MForm 4 → | Mar 13, 8:43 pm EDT | Clay B SiegallPresident and CEO, Director | 18,832 | $11.09 | $208,847 | 701,214 | — | plan? |
| Mar 5, 2018 SForm 4 → | Mar 7, 8:25 pm EST | Jonathan G DrachmanCMO & EVP, R & D | 10,457 | $52.83 | $552,452 | 170,934 | −5.76% | plan? |
| Mar 5, 2018 MForm 4 → | Mar 7, 8:25 pm EST | Jonathan G DrachmanCMO & EVP, R & D | 10,457 | $8.96 | $93,695 | 174,191 | — | plan? |
| Feb 13, 2018 MForm 4 → | Feb 15, 9:21 pm EST | Daniel G WelchDirector | 16,881 | $9.39 | $158,463 | 66,100 | — | plan? |
| Feb 9, 2018 SForm 4 → | Feb 13, 8:19 pm EST | Clay B SiegallPresident and CEO, Director | 18,832 | $49.75 | $936,818 | 687,146 | −2.67% | plan? |
| Feb 9, 2018 MForm 4 → | Feb 13, 8:19 pm EST | Clay B SiegallPresident and CEO, Director | 18,832 | $11.09 | $208,847 | 697,546 | — | plan? |
| Feb 5, 2018 DForm 4 → | Feb 7, 8:17 pm EST | Darren S ClineEVP, Commercial | 1,399 | $55.58 | $77,756 | 75,831 | — | plan? |
| Feb 1, 2018 PForm 4 → | Feb 5, 4:00 pm EST | BAKER BROS. ADVISORS LP +5Director, 10% Owner | 3,846,153 | $52.00 | $199,999,956 | 44,355,335 | +9.49% | plan? |
| Jan 11, 2018 SForm 4 → | Jan 16, 8:08 pm EST | Clay B SiegallPresident and CEO, Director | 18,832 | $51.71 | $973,873 | 687,146 | −2.67% | plan? |
| Jan 11, 2018 MForm 4 → | Jan 16, 8:08 pm EST | Clay B SiegallPresident and CEO, Director | 18,832 | $11.09 | $208,847 | 687,846 | — | plan? |
| Jan 11, 2018 MForm 4 → | Jan 16, 8:04 pm EST | Jonathan G DrachmanCMO & EVP, R & D | 19,416 | $11.06 | $214,705 | 170,934 | — | plan? |
| Dec 11, 2017 SForm 4 → | Dec 13, 8:50 pm EST | Clay B SiegallPresident and CEO, Director | 18,832 | $55.40 | $1,043,329 | 687,146 | −2.67% | plan? |
| Dec 11, 2017 MForm 4 → | Dec 13, 8:50 pm EST | Clay B SiegallPresident and CEO, Director | 18,832 | $11.09 | $208,847 | 688,946 | — | plan? |
| Dec 4, 2017 DForm 4 → | Dec 6, 8:06 pm EST | Jean I LiuGC/EVP, Leg Affairs | 7,536 | $59.55 | $448,769 | 60,864 | — | plan? |
| Dec 4, 2017 SForm 4 → | Dec 6, 8:04 pm EST | Eric DobmeierChief Operating Officer | 3,729 | $58.75 | $219,092 | 117,424 | −3.08% | plan? |
| Dec 4, 2017 MForm 4 → | Dec 6, 8:04 pm EST | Eric DobmeierChief Operating Officer | 6,165 | $32.00 | $197,300 | 119,860 | — | plan? |
| Nov 30, 2017 SForm 4 → | Dec 4, 7:54 pm EST | Vaughn B HimesChief Technical Officer | 10,000 | $59.97 | $599,729 | 164,906 | −5.72% | plan? |
| Nov 30, 2017 MForm 4 → | Dec 4, 7:54 pm EST | Vaughn B HimesChief Technical Officer | 10,000 | $12.16 | $121,573 | 167,337 | — | plan? |
| Nov 15, 2017 SForm 4 → | Nov 17, 8:47 pm EST | Marc E LippmanDirector | 3,000 | $58.07 | $174,224 | 132,050 | −2.22% | plan? |
| Nov 15, 2017 SForm 4 → | Nov 17, 8:45 pm EST | Eric DobmeierChief Operating Officer | 35,000 | $58.25 | $2,038,724 | 117,424 | −23.0% | plan? |
| Nov 15, 2017 MForm 4 → | Nov 17, 8:45 pm EST | Eric DobmeierChief Operating Officer | 35,000 | $20.60 | $721,033 | 127,424 | — | plan? |
| Nov 10, 2017 SForm 4 → | Nov 14, 7:40 pm EST | Clay B SiegallPresident and CEO, Director | 18,832 | $58.00 | $1,092,193 | 687,146 | −2.67% | plan? |
| Nov 10, 2017 MForm 4 → | Nov 14, 7:40 pm EST | Clay B SiegallPresident and CEO, Director | 18,832 | $11.09 | $208,847 | 704,255 | — | plan? |
| Nov 1, 2017 SForm 4 → | Nov 3, 5:42 pm EDT | Todd E SimpsonChief Financial Officer | 39,385 | $60.91 | $2,398,915 | 178,992 | −18.0% | plan? |
| Oct 11, 2017 SForm 4 → | Oct 13, 8:58 pm EDT | Clay B SiegallPresident and CEO, Director | 18,832 | $61.18 | $1,152,234 | 687,146 | −2.67% | plan? |
| Oct 11, 2017 MForm 4 → | Oct 13, 8:58 pm EDT | Clay B SiegallPresident and CEO, Director | 18,832 | $11.09 | $208,847 | 688,943 | — | plan? |
Reported at this company — derivatives (options, RSUs, warrants)
| Trade | Reported (ET) | Insider | Shares | Avg price | Total | Owned after | Δ stake | Flags |
|---|---|---|---|---|---|---|---|---|
| Mar 8, 2019 MForm 4 → | Mar 12, 7:34 pm EDT | Clay B SiegallPresident and CEO, Director | 20,148 | — | — | 100,741 | — | |
| Mar 8, 2019 MForm 4 → | Mar 12, 7:31 pm EDT | Vaughn B HimesChief Technical Officer | 8,000 | — | — | 28,498 | — | |
| Feb 8, 2019 MForm 4 → | Feb 12, 6:25 pm EST | Clay B SiegallSee Remarks, Director | 20,148 | — | — | 120,889 | — | |
| Jan 8, 2019 MForm 4 → | Jan 10, 9:09 pm EST | David W GryskaDirector | 5,000 | — | — | 12,500 | — | |
| Jan 8, 2019 MForm 4 → | Jan 10, 8:27 pm EST | Clay B SiegallPresident and CEO, Director | 20,148 | — | — | 141,037 | — | |
| Dec 10, 2018 MForm 4 → | Dec 12, 7:31 pm EST | Clay B SiegallPresident and CEO, Director | 20,148 | — | — | 161,185 | — | |
| Nov 30, 2018 MForm 4 → | Dec 4, 7:37 pm EST | Vaughn B HimesChief Technical Officer | 5,000 | — | — | 36,498 | — | |
| Nov 8, 2018 MForm 4 → | Nov 9, 5:54 pm EST | Clay B SiegallPresident and CEO, Director | 20,148 | — | — | 181,333 | — | |
| Oct 30, 2018 MForm 4 → | Nov 1, 5:55 pm EDT | Srinivas AkkarajuDirector | 5,000 | — | — | 0 | — | |
| Oct 8, 2018 MForm 4 → | Oct 9, 8:13 pm EDT | Clay B SiegallPresident and CEO, Director | 20,148 | — | — | 201,481 | — | |
| Sep 17, 2018 MForm 4 → | Sep 19, 6:36 pm EDT | Clay B SiegallPresident and CEO, Director | 20,148 | — | — | 221,629 | — | |
| Sep 7, 2018 AForm 4 → | Sep 11, 7:29 pm EDT | Roger D DanseyChief Medical Officer | 14,010 | — | — | 14,010 | — | |
| Sep 7, 2018 MForm 4 → | Sep 11, 7:26 pm EDT | Vaughn B HimesChief Technical Officer | 5,000 | — | — | 41,498 | — | |
| Aug 30, 2018 AForm 4 → | Sep 4, 8:58 pm EDT | Todd E SimpsonChief Financial Officer | 49,205 | — | — | 47,904 | — | |
| Aug 30, 2018 AForm 4 → | Sep 4, 8:56 pm EDT | Jean I LiuGC/EVP, Leg Affairs | 41,824 | — | — | 40,523 | — | |
| Aug 30, 2018 AForm 4 → | Sep 4, 8:54 pm EDT | Vaughn B HimesChief Technical Officer | 42,644 | — | — | 41,343 | — | |
| Aug 30, 2018 AForm 4 → | Sep 4, 8:49 pm EDT | Roger D DanseyChief Medical Officer | 3,189 | — | — | 3,189 | — | |
| Aug 30, 2018 AForm 4 → | Sep 4, 8:41 pm EDT | Darren S ClineEVP, Commercial | 44,285 | — | — | 42,984 | — | |
| Aug 30, 2018 AForm 4 → | Sep 4, 8:36 pm EDT | Clay B SiegallPresident and CEO, Director | 227,984 | — | — | 226,683 | — | |
| Aug 9, 2018 MForm 4 → | Aug 13, 4:47 pm EDT | Clay B SiegallSee Remarks, Director | 18,831 | — | — | 0 | — | |
| Jul 9, 2018 MForm 4 → | Jul 11, 8:28 pm EDT | Clay B SiegallPresident and CEO, Director | 18,832 | — | — | 18,831 | — | |
| Jun 15, 2018 AForm 4 → | Jun 19, 7:57 pm EDT | Roger D DanseyChief Medical Officer | 50,000 | — | — | 43,860 | — | |
| Jun 12, 2018 MForm 4 → | Jun 14, 6:31 pm EDT | Darren S ClineEVP, Commercial | 10,086 | — | — | 1,583 | — | |
| Jun 8, 2018 MForm 4 → | Jun 12, 7:34 pm EDT | Clay B SiegallPresident and CEO, Director | 18,832 | — | — | 37,663 | — | |
| May 31, 2018 MForm 4 → | Jun 4, 7:11 pm EDT | Vaughn B HimesChief Technical Officer | 5,000 | — | — | 46,498 | — | |
| May 18, 2018 AForm 4 → | May 22, 8:16 pm EDT | Srinivas AkkarajuDirector | 9,260 | — | — | 9,260 | — | |
| May 18, 2018 AForm 4 → | May 22, 8:13 pm EDT | Daniel G WelchDirector | 9,260 | — | — | 9,260 | — | |
| May 18, 2018 AForm 4 → | May 22, 8:10 pm EDT | Nancy A SimonianDirector | 9,260 | — | — | 9,260 | — | |
| May 18, 2018 AForm 4 → | May 22, 8:09 pm EDT | John A OrwinDirector | 9,260 | — | — | 9,260 | — | |
| May 18, 2018 AForm 4 → | May 22, 8:07 pm EDT | Marc E LippmanDirector | 9,260 | — | — | 9,260 | — | |
| May 18, 2018 AForm 4 → | May 22, 8:06 pm EDT | David W GryskaDirector | 9,260 | — | — | 9,260 | — | |
| May 18, 2018 AForm 4 → | May 18, 4:25 pm EDT | BAKER BROS. ADVISORS LP +5Director, 10% Owner | 18,520 | — | — | 9,260 | — | |
| May 9, 2018 MForm 4 → | May 11, 8:01 pm EDT | Clay B SiegallPresident and CEO, Director | 18,832 | — | — | 56,495 | — | |
| May 9, 2018 MForm 4 → | May 11, 7:59 pm EDT | Darren S ClineEVP, Commercial | 9,000 | — | — | 892 | — | |
| Apr 30, 2018 MForm 4 → | May 2, 6:05 pm EDT | BAKER BROS. ADVISORS LP +5Director, 10% Owner | 20,000 | — | — | 0 | — | |
| Apr 9, 2018 MForm 4 → | Apr 11, 8:38 pm EDT | Clay B SiegallPresident and CEO, Director | 18,832 | — | — | 75,327 | — | |
| Mar 20, 2018 AForm 4 → | Mar 22, 9:36 pm EDT | Jonathan G DrachmanSee Remarks | 10,526 | — | — | 10,526 | — | |
| Mar 20, 2018 AForm 4 → | Mar 22, 9:36 pm EDT | Darren S ClineSee Remarks | 8,333 | — | — | 8,333 | — | |
| Mar 20, 2018 AForm 4 → | Mar 22, 9:34 pm EDT | Jean I LiuGC & EVP, Legal Affairs | 8,333 | — | — | 8,333 | — | |
| Mar 20, 2018 AForm 4 → | Mar 22, 9:32 pm EDT | Todd E SimpsonChief Financial Officer | 10,526 | — | — | 10,526 | — | |
| Mar 20, 2018 AForm 4 → | Mar 22, 9:32 pm EDT | Clay B SiegallPresident & CEO, Director | 37,280 | — | — | 37,280 | — | |
| Mar 20, 2018 AForm 4 → | Mar 22, 9:30 pm EDT | Vaughn B HimesChief Technical Officer | 8,333 | — | — | 8,333 | — | |
| Mar 20, 2018 MForm 4 → | Mar 22, 7:04 pm EDT | Jonathan G DrachmanCMO & EVP, R & D | 31,039 | — | — | 45,000 | — | |
| Mar 15, 2018 MForm 4 → | Mar 19, 7:35 pm EDT | Vaughn B HimesSee Remarks | 5,000 | — | — | 51,498 | — | |
| Mar 15, 2018 AForm 4 → | Mar 15, 9:34 pm EDT | Alpna SethDirector | 14,250 | — | — | 14,250 | — | |
| Mar 9, 2018 MForm 4 → | Mar 13, 8:43 pm EDT | Clay B SiegallPresident and CEO, Director | 18,832 | — | — | 94,159 | — | |
| Mar 5, 2018 MForm 4 → | Mar 7, 8:25 pm EST | Jonathan G DrachmanCMO & EVP, R & D | 10,457 | — | — | 0 | — | |
| Feb 13, 2018 MForm 4 → | Feb 15, 9:21 pm EST | Daniel G WelchDirector | 16,881 | — | — | 0 | — | |
| Feb 9, 2018 MForm 4 → | Feb 13, 8:19 pm EST | Clay B SiegallPresident and CEO, Director | 18,832 | — | — | 112,991 | — | |
| Jan 11, 2018 MForm 4 → | Jan 16, 8:08 pm EST | Clay B SiegallPresident and CEO, Director | 18,832 | — | — | 131,823 | — | |
| Jan 11, 2018 MForm 4 → | Jan 16, 8:04 pm EST | Jonathan G DrachmanCMO & EVP, R & D | 19,416 | — | — | 7,000 | — | |
| Dec 11, 2017 MForm 4 → | Dec 13, 8:50 pm EST | Clay B SiegallPresident and CEO, Director | 18,832 | — | — | 150,655 | — | |
| Dec 4, 2017 MForm 4 → | Dec 6, 8:04 pm EST | Eric DobmeierChief Operating Officer | 6,165 | — | — | 24,700 | — | |
| Nov 30, 2017 MForm 4 → | Dec 4, 7:54 pm EST | Vaughn B HimesChief Technical Officer | 10,000 | — | — | 0 | — | |
| Nov 15, 2017 MForm 4 → | Nov 17, 8:45 pm EST | Eric DobmeierChief Operating Officer | 35,000 | — | — | 28,429 | — | |
| Nov 10, 2017 MForm 4 → | Nov 14, 7:40 pm EST | Clay B SiegallPresident and CEO, Director | 18,832 | — | — | 169,487 | — | |
| Oct 11, 2017 MForm 4 → | Oct 13, 8:58 pm EDT | Clay B SiegallPresident and CEO, Director | 18,832 | — | — | 188,319 | — | |
| Oct 5, 2017 MForm 4 → | Oct 10, 6:42 pm EDT | Jonathan G DrachmanCMO & EVP, R & D | 17,816 | — | — | 0 | — | late |
| Sep 26, 2017 MForm 4 → | Sep 28, 6:15 pm EDT | Clay B SiegallPresident and CEO, Director | 9,017 | — | — | 0 | — | |
| Sep 11, 2017 MForm 4 → | Sep 12, 7:34 pm EDT | Clay B SiegallPresident and CEO, Director | 18,832 | — | — | 207,151 | — | |
| Sep 8, 2017 MForm 4 → | Sep 12, 7:32 pm EDT | Vaughn B HimesChief Technical Officer | 10,000 | — | — | 9,831 | — | |
| Sep 6, 2017 MForm 4 → | Sep 8, 7:32 pm EDT | Darren S ClineEVP, Commercial | 10,048 | — | — | 2,268 | — | |
| Aug 31, 2017 MForm 4 → | Sep 5, 7:25 pm EDT | Eric DobmeierChief Operating Officer | 25,000 | — | — | 18,089 | — | |
| Aug 31, 2017 MForm 4 → | Sep 5, 7:23 pm EDT | Darren S ClineEVP, Commercial | 2,907 | — | — | 0 | — | |
| Aug 24, 2017 MForm 4 → | Aug 25, 7:52 pm EDT | Jonathan G DrachmanCMO & EVP, R & D | 10,000 | — | — | 0 | — | |
| Aug 17, 2017 AForm 4 → | Aug 18, 8:38 pm EDT | Todd E SimpsonChief Financial Officer | 57,500 | — | — | 55,344 | — | |
| Aug 17, 2017 AForm 4 → | Aug 18, 8:35 pm EDT | Clay B SiegallPresident and CEO, Director | 168,000 | — | — | 165,844 | — | |
| Aug 17, 2017 AForm 4 → | Aug 18, 8:32 pm EDT | Jean I LiuGC/EVP, Leg Affairs | 42,500 | — | — | 40,344 | — | |
| Aug 17, 2017 AForm 4 → | Aug 18, 8:26 pm EDT | Vaughn B HimesChief Technical Officer | 50,000 | — | — | 47,844 | — | |
| Aug 17, 2017 AForm 4 → | Aug 18, 8:23 pm EDT | Jonathan G DrachmanCMO & EVP, R & D | 67,500 | — | — | 65,344 | — | |
| Aug 17, 2017 AForm 4 → | Aug 18, 8:20 pm EDT | Eric DobmeierChief Operating Officer | 87,500 | — | — | 85,344 | — | |
| Aug 17, 2017 AForm 4 → | Aug 18, 8:12 pm EDT | Darren S ClineEVP, Commercial | 42,500 | — | — | 40,344 | — | |
| Aug 7, 2017 MForm 4 → | Aug 9, 6:58 pm EDT | Clay B SiegallPresident and CEO, Director | 10,413 | — | — | 0 | — | |
| Aug 7, 2017 MForm 4 → | Aug 9, 6:52 pm EDT | Darren S ClineEVP, Commercial | 6,000 | — | — | 2,907 | — | |
| Jul 27, 2017 MForm 4 → | Jul 31, 7:15 pm EDT | Jonathan G DrachmanCMO & EVP, R & D | 10,000 | — | — | 10,000 | — | |
| Jul 5, 2017 MForm 4 → | Jul 7, 7:20 pm EDT | Clay B SiegallPresident and CEO, Director | 10,423 | — | — | 10,413 | — | |
| Jun 22, 2017 MForm 4 → | Jun 26, 6:25 pm EDT | Jonathan G DrachmanCMO & EVP, R & D | 10,000 | — | — | 20,000 | — | |
| Jun 5, 2017 MForm 4 → | Jun 7, 7:24 pm EDT | Clay B SiegallPresident and CEO, Director | 10,423 | — | — | 20,836 | — | |
| May 31, 2017 MForm 4 → | Jun 2, 7:08 pm EDT | Vaughn B HimesChief Technical Officer | 10,000 | — | — | 3,164 | — | |
| May 19, 2017 AForm 4 → | May 23, 7:24 pm EDT | Daniel G WelchDirector | 9,260 | — | — | 9,260 | — | |
| May 19, 2017 AForm 4 → | May 23, 7:22 pm EDT | Nancy A SimonianDirector | 9,260 | — | — | 9,260 | — | |
| May 19, 2017 AForm 4 → | May 23, 7:19 pm EDT | John A OrwinDirector | 9,260 | — | — | 9,260 | — | |
| May 19, 2017 AForm 4 → | May 23, 7:17 pm EDT | Marc E LippmanDirector | 9,260 | — | — | 9,260 | — | |
| May 19, 2017 AForm 4 → | May 23, 7:15 pm EDT | David W GryskaDirector | 9,260 | — | — | 9,260 | — | |
| May 19, 2017 AForm 4 → | May 23, 7:08 pm EDT | Srinivas AkkarajuDirector | 9,260 | — | — | 9,260 | — | |
| May 19, 2017 AForm 4 → | May 23, 5:11 pm EDT | BAKER BROS. ADVISORS LP +5Director, 10% Owner | 18,520 | — | — | 9,260 | — | |
| May 15, 2017 MForm 4 → | May 17, 5:26 pm EDT | BAKER BROS. ADVISORS LP +5Director, 10% Owner | 20,000 | — | — | 0 | — | |
| May 5, 2017 MForm 4 → | May 9, 7:42 pm EDT | Clay B SiegallPresident and CEO, Director | 14,462 | — | — | 31,259 | — | |
| Apr 5, 2017 MForm 4 → | Apr 6, 8:10 pm EDT | Clay B SiegallPresident and CEO, Director | 14,465 | — | — | 41,682 | — | |
| Mar 31, 2017 MForm 4 → | Apr 4, 5:48 pm EDT | Vaughn B HimesChief Technical Officer | 10,000 | — | — | 13,164 | — | |
| Mar 6, 2017 MForm 4 → | Mar 8, 7:22 pm EST | Clay B SiegallPresident and CEO, Director | 14,465 | — | — | 52,105 | — | |
| Feb 6, 2017 MForm 4 → | Feb 8, 5:29 pm EST | Clay B SiegallPresident and CEO, Director | 14,465 | — | — | 62,528 | — | |
| Jan 25, 2017 MForm 4 → | Jan 26, 7:41 pm EST | Jonathan G DrachmanCMO & EVP, R & D | 5,000 | — | — | 0 | — | |
| Jan 6, 2017 MForm 4 → | Jan 10, 6:11 pm EST | Clay B SiegallPresident and CEO, Director | 14,465 | — | — | 72,951 | — | |
| Dec 16, 2016 MForm 4 → | Dec 20, 7:48 pm EST | Darren S ClineEVP, Commercial | 3,100 | — | — | 5,024 | — | |
| Dec 13, 2016 MForm 4 → | Dec 15, 7:26 pm EST | Darren S ClineEVP, Commercial | 12,761 | — | — | 926 | — | |
| Dec 12, 2016 MForm 4 → | Dec 14, 5:35 pm EST | Vaughn B HimesChief Technical Officer | 15,632 | — | — | 0 | — | |
| Dec 8, 2016 MForm 4 → | Dec 12, 7:24 pm EST | Eric DobmeierChief Operating Officer | 12,500 | — | — | 0 | — | |
| Dec 7, 2016 MForm 4 → | Dec 8, 8:05 pm EST | Vaughn B HimesChief Technical Officer | 30,000 | — | — | 23,164 | — | |
| Dec 6, 2016 MForm 4 → | Dec 8, 8:03 pm EST | Clay B SiegallPresident and CEO, Director | 14,465 | — | — | 83,374 | — |