SEC Form 4 · accession 0001231919-26-000938
Septerna, Inc. · SEPN
Statement of changes in beneficial ownership, as filed. Original on EDGAR ↗
Reporting owners
RA Capital Healthcare Fund LP
Director · 10% Owner
RA CAPITAL MANAGEMENT, L.P.
Director · 10% Owner
Peter Kolchinsky
Director · 10% Owner
Rajeev M. Shah
Director · 10% Owner
RA Capital Nexus Fund III, L.P.
Director
Period of report
Aug 12, 2026
Accepted (ET)
Aug 14, 2026 · 5:11 pm EDT
Rule 10b5-1 plan
box not checked
Issuer CIK
0001984086
Table I — non-derivative securities
| Security | Date | Code | Shares | Price | A/D | Owned after | D/I | Nature of ownership |
|---|---|---|---|---|---|---|---|---|
| Common StockF1,F2 | Aug 12, 2026 | S | 746,500 | $42.50 | D | 4,777,415 | I | See footnotes |
| Common StockF1,F3 | Aug 12, 2026 | S | 746,500 | $42.50 | D | 725,443 | I | See footnotes |
Table II — derivative securities
No Table II lines on this filing.
Explanation of responses
- F1RA Capital Management, L.P. (the "Adviser") is the investment manager for RA Capital Healthcare Fund, L.P. (the "Fund") and RA Capital Nexus Fund III, L.P. (the "Nexus Fund III"). The general partner of the Adviser is RA Capital Management GP, LLC (the "Adviser GP"), of which Dr. Peter Kolchinsky and Mr. Rajeev Shah are the managing members. Each of the Adviser, the Adviser GP, the Fund, the Nexus Fund III, Dr. Kolchinsky and Mr. Shah disclaims beneficial ownership of any of the reported securities, except to the extent of its or his respective pecuniary interest therein.
- F2Held directly by the Fund.
- F3Held directly by the Nexus Fund III.
Remarks
Jake Simson, a Partner of the Adviser, serves on the Issuer's board of directors.