Company · CIK 0001503802 · SIC 2834 — Pharmaceutical Preparations · Nasdaq
Karyopharm Therapeutics Inc. · KPTI
Insider activity reported against this company. All insider holders · On EDGAR ↗
Reported at this company — common stock
| Trade | Reported (ET) | Insider | Shares | Avg price | Total | Owned after | Δ stake | Flags |
|---|---|---|---|---|---|---|---|---|
| Sep 1, 2026 SForm 4 → | Sep 2, 4:57 pm EDT | Kristin AbateChief Accounting Officer | 19 | $2.02 | $38 | 23,782 | −0.08% | |
| Jul 28, 2026 SForm 4 → | Jul 30, 4:42 pm EDT | Stuart PoultonEVP, Chief Development Officer | 189 | $7.10 | $1,342 | 94,632 | −0.20% | |
| Feb 28, 2019 SForm 4 → | Mar 4, 8:28 pm EST | Chione Ltd +410% Owner | 149,624 | $4.14 | $619,114 | 6,000,000 | −2.43% | plan? |
| Feb 25, 2019 SForm 4 → | Feb 27, 8:12 pm EST | Chione Ltd +410% Owner | 1,481,643 | $4.81 | $7,127,924 | 6,149,624 | −19.4% | plan? |
| Jan 7, 2019 SForm 4 → | Jan 9, 4:41 pm EST | Michael KauffmanChief Executive Officer, Director | 12,500 | $10.23 | $127,824 | 731,134 | −1.68% | plan? |
| Jan 7, 2019 MForm 4 → | Jan 9, 4:41 pm EST | Michael KauffmanChief Executive Officer, Director | 12,500 | $0.033 | $413 | 743,634 | — | plan? |
| Jan 7, 2019 SForm 4 → | Jan 9, 4:37 pm EST | Sharon ShachamPresident & CSO | 12,500 | $10.23 | $127,824 | 731,134 | −1.68% | plan? |
| Jan 7, 2019 MForm 4 → | Jan 9, 4:37 pm EST | Sharon ShachamPresident & CSO | 12,500 | $0.033 | $413 | 743,634 | — | plan? |
| Dec 7, 2018 SForm 4 → | Dec 10, 4:29 pm EST | Michael KauffmanChief Executive Officer, Director | 12,500 | $10.11 | $126,423 | 713,510 | −1.72% | plan? |
| Dec 7, 2018 MForm 4 → | Dec 10, 4:29 pm EST | Michael KauffmanChief Executive Officer, Director | 12,500 | $0.033 | $413 | 726,010 | — | plan? |
| Dec 7, 2018 SForm 4 → | Dec 10, 4:28 pm EST | Sharon ShachamPresident & CSO | 12,500 | $10.11 | $126,423 | 713,510 | −1.72% | plan? |
| Dec 7, 2018 MForm 4 → | Dec 10, 4:28 pm EST | Sharon ShachamPresident & CSO | 12,500 | $0.033 | $413 | 726,010 | — | plan? |
| Nov 26, 2018 SForm 4 → | Nov 27, 4:20 pm EST | Sharon ShachamPresident & CSO | 9,600 | $11.00 | $105,600 | 512,143 | −1.84% | plan? |
| Nov 26, 2018 MForm 4 → | Nov 27, 4:20 pm EST | Sharon ShachamPresident & CSO | 9,600 | $4.75 | $45,619 | 521,743 | — | plan? |
| Nov 26, 2018 SForm 4 → | Nov 27, 4:17 pm EST | Michael KauffmanChief Executive Officer, Director | 9,600 | $11.00 | $105,600 | 512,143 | −1.84% | plan? |
| Nov 26, 2018 MForm 4 → | Nov 27, 4:17 pm EST | Michael KauffmanChief Executive Officer, Director | 9,600 | $4.75 | $45,619 | 521,743 | — | plan? |
| Nov 19, 2018 SForm 4 → | Nov 21, 8:03 am EST | Sharon ShachamPresident & CSO | 400 | $11.14 | $4,455 | 512,143 | −0.08% | plan? |
| Nov 19, 2018 MForm 4 → | Nov 21, 8:03 am EST | Sharon ShachamPresident & CSO | 400 | $4.75 | $1,901 | 512,543 | — | plan? |
| Nov 19, 2018 SForm 4 → | Nov 21, 8:00 am EST | Michael KauffmanChief Executive Officer, Director | 400 | $11.14 | $4,455 | 512,143 | −0.08% | plan? |
| Nov 19, 2018 MForm 4 → | Nov 21, 8:00 am EST | Michael KauffmanChief Executive Officer, Director | 400 | $4.75 | $1,901 | 512,543 | — | plan? |
| Nov 7, 2018 SForm 4 → | Nov 9, 4:17 pm EST | Michael KauffmanChief Executive Officer, Director | 12,500 | $11.65 | $145,593 | 713,510 | −1.72% | plan? |
| Nov 7, 2018 MForm 4 → | Nov 9, 4:17 pm EST | Michael KauffmanChief Executive Officer, Director | 12,500 | $0.033 | $413 | 726,010 | — | plan? |
| Nov 7, 2018 SForm 4 → | Nov 9, 4:16 pm EST | Sharon ShachamPresident & CSO | 12,500 | $11.65 | $145,593 | 713,510 | −1.72% | plan? |
| Nov 7, 2018 MForm 4 → | Nov 9, 4:16 pm EST | Sharon ShachamPresident & CSO | 12,500 | $0.033 | $413 | 726,010 | — | plan? |
| Oct 18, 2018 SForm 4 → | Oct 22, 4:09 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $12.63 | $126,304 | 512,143 | −1.92% | plan? |
| Oct 18, 2018 MForm 4 → | Oct 22, 4:09 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $4.75 | $47,520 | 522,143 | — | plan? |
| Oct 18, 2018 SForm 4 → | Oct 22, 4:06 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $12.63 | $126,304 | 512,143 | −1.92% | plan? |
| Oct 18, 2018 MForm 4 → | Oct 22, 4:06 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $4.75 | $47,520 | 522,143 | — | plan? |
| Oct 8, 2018 SForm 4 → | Oct 9, 8:05 am EDT | Michael KauffmanChief Executive Officer, Director | 12,500 | $15.75 | $196,832 | 713,510 | −1.72% | plan? |
| Oct 8, 2018 MForm 4 → | Oct 9, 8:05 am EDT | Michael KauffmanChief Executive Officer, Director | 12,500 | $0.033 | $413 | 726,010 | — | plan? |
| Oct 8, 2018 SForm 4 → | Oct 9, 8:00 am EDT | Sharon ShachamPresident & CSO | 12,500 | $15.75 | $196,832 | 713,510 | −1.72% | plan? |
| Oct 8, 2018 MForm 4 → | Oct 9, 8:00 am EDT | Sharon ShachamPresident & CSO | 12,500 | $0.033 | $413 | 726,010 | — | plan? |
| Sep 18, 2018 SForm 4 → | Sep 18, 5:26 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $18.26 | $182,615 | 512,143 | −1.92% | plan? |
| Sep 18, 2018 MForm 4 → | Sep 18, 5:26 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $4.75 | $47,520 | 522,143 | — | plan? |
| Sep 18, 2018 SForm 4 → | Sep 18, 5:23 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $18.26 | $182,615 | 512,143 | −1.92% | plan? |
| Sep 18, 2018 MForm 4 → | Sep 18, 5:23 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $4.75 | $47,520 | 522,143 | — | plan? |
| Sep 10, 2018 SForm 4 → | Sep 11, 6:08 pm EDT | Christopher Brett PrimianoEVP, CBO, GC & Secretary | 10,000 | $18.90 | $189,046 | 2,881 | −77.6% | plan? |
| Sep 10, 2018 MForm 4 → | Sep 11, 6:08 pm EDT | Christopher Brett PrimianoEVP, CBO, GC & Secretary | 10,000 | $8.47 | $84,650 | 12,881 | — | plan? |
| Sep 7, 2018 SForm 4 → | Sep 10, 4:13 pm EDT | Michael KauffmanChief Executive Officer, Director | 12,500 | $19.31 | $241,384 | 713,510 | −1.72% | plan? |
| Sep 7, 2018 MForm 4 → | Sep 10, 4:13 pm EDT | Michael KauffmanChief Executive Officer, Director | 12,500 | $0.033 | $413 | 726,010 | — | plan? |
| Sep 7, 2018 SForm 4 → | Sep 10, 4:11 pm EDT | Sharon ShachamPresident & CSO | 12,500 | $19.31 | $241,384 | 713,510 | −1.72% | plan? |
| Sep 7, 2018 MForm 4 → | Sep 10, 4:11 pm EDT | Sharon ShachamPresident & CSO | 12,500 | $0.033 | $413 | 726,010 | — | plan? |
| Sep 5, 2018 SForm 4 → | Sep 7, 6:27 pm EDT | Chione Ltd +410% Owner | 164,800 | $21.05 | $3,468,730 | 7,631,267 | −2.11% | plan? |
| Aug 30, 2018 SForm 4 → | Sep 4, 6:59 pm EDT | Chione Ltd +410% Owner | 251,468 | $20.94 | $5,265,368 | 7,796,067 | −3.12% | plan? |
| Aug 30, 2018 SForm 4 → | Sep 4, 4:10 pm EDT | Mansoor Raza MirzaDirector | 2,500 | $21.00 | $52,500 | 0 | −100% | plan? |
| Aug 30, 2018 MForm 4 → | Sep 4, 4:10 pm EDT | Mansoor Raza MirzaDirector | 2,500 | $1.92 | $4,810 | 264 | — | plan? |
| Aug 29, 2018 SForm 4 → | Aug 30, 4:38 pm EDT | Mansoor Raza MirzaDirector | 2,500 | $20.00 | $50,000 | 0 | −100% | plan? |
| Aug 29, 2018 MForm 4 → | Aug 30, 4:38 pm EDT | Mansoor Raza MirzaDirector | 2,500 | $1.49 | $3,713 | 2,500 | — | plan? |
| Aug 27, 2018 SForm 4 → | Aug 29, 8:12 pm EDT | Chione Ltd +410% Owner | 214,026 | $19.52 | $4,178,056 | 8,047,535 | −2.59% | plan? |
| Aug 20, 2018 SForm 4 → | Aug 21, 4:14 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $17.46 | $174,568 | 512,143 | −1.92% | plan? |
| Aug 20, 2018 MForm 4 → | Aug 21, 4:14 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $4.75 | $47,520 | 522,143 | — | plan? |
| Aug 20, 2018 SForm 4 → | Aug 21, 4:11 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $17.46 | $174,568 | 512,143 | −1.92% | plan? |
| Aug 20, 2018 MForm 4 → | Aug 21, 4:11 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $4.75 | $47,520 | 522,143 | — | plan? |
| Aug 10, 2018 SForm 4 → | Aug 14, 7:08 pm EDT | Chione Ltd +410% Owner | 702 | $18.50 | $12,987 | 8,261,561 | −0.01% | plan? |
| Aug 7, 2018 SForm 4 → | Aug 9, 8:24 pm EDT | Chione Ltd +410% Owner | 80,876 | $18.52 | $1,498,077 | 8,262,263 | −0.97% | plan? |
| Aug 7, 2018 SForm 4 → | Aug 8, 4:08 pm EDT | Michael KauffmanChief Executive Officer, Director | 12,500 | $18.04 | $225,556 | 713,510 | −1.72% | plan? |
| Aug 7, 2018 MForm 4 → | Aug 8, 4:08 pm EDT | Michael KauffmanChief Executive Officer, Director | 12,500 | $0.033 | $413 | 726,010 | — | plan? |
| Aug 7, 2018 SForm 4 → | Aug 8, 4:04 pm EDT | Sharon ShachamPresident & CSO | 12,500 | $18.04 | $225,556 | 713,510 | −1.72% | plan? |
| Aug 7, 2018 MForm 4 → | Aug 8, 4:04 pm EDT | Sharon ShachamPresident & CSO | 12,500 | $0.033 | $413 | 726,010 | — | plan? |
| Jul 23, 2018 SForm 4 → | Jul 25, 7:55 pm EDT | Chione Ltd +410% Owner | 30,039 | $18.65 | $560,135 | 8,343,139 | −0.36% | plan? |
| Jul 19, 2018 SForm 4 → | Jul 23, 5:00 pm EDT | Chione Ltd +410% Owner | 126,742 | $18.97 | $2,403,745 | 8,373,178 | −1.49% | plan? |
| Jul 18, 2018 SForm 4 → | Jul 20, 4:28 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $18.27 | $182,686 | 512,143 | −1.92% | plan? |
| Jul 18, 2018 MForm 4 → | Jul 20, 4:28 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $2.17 | $21,678 | 522,143 | — | plan? |
| Jul 18, 2018 SForm 4 → | Jul 20, 4:23 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $18.27 | $182,686 | 512,143 | −1.92% | plan? |
| Jul 18, 2018 MForm 4 → | Jul 20, 4:23 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $2.17 | $21,678 | 522,143 | — | plan? |
| Jul 16, 2018 SForm 4 → | Jul 18, 7:34 pm EDT | Chione Ltd +410% Owner | 50,000 | $18.52 | $926,067 | 8,499,920 | −0.58% | plan? |
| Jul 9, 2018 SForm 4 → | Jul 10, 4:10 pm EDT | Michael KauffmanChief Executive Officer, Director | 12,500 | $18.72 | $233,990 | 713,510 | −1.72% | plan? |
| Jul 9, 2018 MForm 4 → | Jul 10, 4:10 pm EDT | Michael KauffmanChief Executive Officer, Director | 12,500 | $0.033 | $413 | 726,010 | — | plan? |
| Jul 9, 2018 SForm 4 → | Jul 10, 4:09 pm EDT | Sharon ShachamPresident & CSO | 12,500 | $18.72 | $233,990 | 713,510 | −1.72% | plan? |
| Jul 9, 2018 MForm 4 → | Jul 10, 4:09 pm EDT | Sharon ShachamPresident & CSO | 12,500 | $0.033 | $413 | 726,010 | — | plan? |
| Jun 18, 2018 SForm 4 → | Jun 19, 4:06 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $18.66 | $186,558 | 512,143 | −1.92% | plan? |
| Jun 18, 2018 MForm 4 → | Jun 19, 4:06 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $0.264 | $2,640 | 522,143 | — | plan? |
| Jun 18, 2018 SForm 4 → | Jun 19, 4:05 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $18.66 | $186,558 | 512,143 | −1.92% | plan? |
| Jun 18, 2018 MForm 4 → | Jun 19, 4:05 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $0.264 | $2,640 | 522,143 | — | plan? |
| Jun 7, 2018 SForm 4 → | Jun 11, 4:17 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $17.30 | $172,991 | 713,510 | −1.38% | plan? |
| Jun 7, 2018 MForm 4 → | Jun 11, 4:17 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $0.257 | $2,570 | 723,510 | — | plan? |
| Jun 7, 2018 SForm 4 → | Jun 11, 4:11 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $17.30 | $172,991 | 713,510 | −1.38% | plan? |
| Jun 7, 2018 MForm 4 → | Jun 11, 4:11 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $0.257 | $2,570 | 723,510 | — | plan? |
| May 18, 2018 SForm 4 → | May 21, 4:28 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $19.39 | $193,870 | 512,143 | −1.92% | plan? |
| May 18, 2018 MForm 4 → | May 21, 4:28 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $0.264 | $2,640 | 522,143 | — | plan? |
| May 18, 2018 SForm 4 → | May 21, 4:26 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $19.39 | $193,870 | 512,143 | −1.92% | plan? |
| May 18, 2018 MForm 4 → | May 21, 4:26 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $0.264 | $2,640 | 522,143 | — | plan? |
| May 10, 2018 SForm 4 → | May 11, 4:08 pm EDT | Mansoor Raza MirzaDirector | 2,000 | $18.00 | $36,000 | 0 | −100% | plan? |
| May 10, 2018 MForm 4 → | May 11, 4:08 pm EDT | Mansoor Raza MirzaDirector | 2,000 | $1.07 | $2,146 | 1,325 | — | plan? |
| May 10, 2018 SForm 4 → | May 10, 4:10 pm EDT | Christopher Brett PrimianoEVP, CBO, GC & Secretary | 2,000 | $18.01 | $36,024 | 2,881 | −41.0% | plan? |
| May 7, 2018 SForm 4 → | May 8, 4:21 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $16.77 | $167,747 | 713,510 | −1.38% | plan? |
| May 7, 2018 MForm 4 → | May 8, 4:21 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $0.264 | $2,640 | 723,510 | — | plan? |
| May 7, 2018 SForm 4 → | May 8, 4:19 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $16.77 | $167,747 | 713,510 | −1.38% | plan? |
| May 7, 2018 MForm 4 → | May 8, 4:19 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $0.264 | $2,640 | 723,510 | — | plan? |
| Apr 18, 2018 SForm 4 → | Apr 20, 4:07 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $14.79 | $147,878 | 512,143 | −1.92% | plan? |
| Apr 18, 2018 MForm 4 → | Apr 20, 4:07 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $0.264 | $2,640 | 522,143 | — | plan? |
| Apr 18, 2018 SForm 4 → | Apr 20, 4:06 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $14.79 | $147,878 | 512,143 | −1.92% | plan? |
| Apr 18, 2018 MForm 4 → | Apr 20, 4:06 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $0.264 | $2,640 | 522,143 | — | plan? |
| Apr 9, 2018 SForm 4 → | Apr 10, 4:20 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $12.48 | $124,829 | 713,510 | −1.38% | plan? |
| Apr 9, 2018 MForm 4 → | Apr 10, 4:20 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $0.264 | $2,640 | 723,510 | — | plan? |
| Apr 9, 2018 SForm 4 → | Apr 10, 4:17 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $12.48 | $124,829 | 713,510 | −1.38% | plan? |
| Apr 9, 2018 MForm 4 → | Apr 10, 4:17 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $0.264 | $2,640 | 723,510 | — | plan? |
| Mar 19, 2018 SForm 4 → | Mar 20, 4:36 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $15.29 | $152,895 | 512,143 | −1.92% | plan? |
| Mar 19, 2018 MForm 4 → | Mar 20, 4:36 pm EDT | Sharon ShachamPresident & CSO | 10,000 | $0.264 | $2,640 | 522,143 | — | plan? |
| Mar 19, 2018 SForm 4 → | Mar 20, 4:34 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | $15.29 | $152,895 | 512,143 | −1.92% | plan? |
Reported at this company — derivatives (options, RSUs, warrants)
| Trade | Reported (ET) | Insider | Shares | Avg price | Total | Owned after | Δ stake | Flags |
|---|---|---|---|---|---|---|---|---|
| Feb 25, 2019 AForm 4 → | Feb 25, 5:14 pm EST | Michael MasonSVP, CFO & Treasurer | 150,000 | — | — | 150,000 | — | |
| Feb 15, 2019 AForm 4 → | Feb 19, 4:32 pm EST | Cameron PetersVP of Finance | 25,500 | — | — | 8,500 | — | |
| Feb 15, 2019 AForm 4 → | Feb 19, 4:30 pm EST | Anand VaradanEVP, Chief Commercial Officer | 141,500 | — | — | 38,700 | — | |
| Feb 15, 2019 AForm 4 → | Feb 19, 4:29 pm EST | Christopher Brett PrimianoEVP, CBO, GC & Secretary | 141,500 | — | — | 38,700 | — | |
| Feb 15, 2019 AForm 4 → | Feb 19, 4:27 pm EST | Ran FrenkelChief Dev Operations Officer | 141,500 | — | — | 38,700 | — | |
| Feb 15, 2019 AForm 4 → | Feb 19, 4:25 pm EST | Sharon ShachamPresident & CSO | 636,800 | — | — | 87,200 | — | |
| Feb 15, 2019 AForm 4 → | Feb 19, 4:23 pm EST | Michael KauffmanChief Executive Officer, Director | 636,800 | — | — | 87,200 | — | |
| Jan 7, 2019 MForm 4 → | Jan 9, 4:41 pm EST | Michael KauffmanChief Executive Officer, Director | 12,500 | — | — | 15,357 | — | |
| Jan 7, 2019 MForm 4 → | Jan 9, 4:37 pm EST | Sharon ShachamPresident & CSO | 12,500 | — | — | 15,357 | — | |
| Dec 7, 2018 MForm 4 → | Dec 10, 4:29 pm EST | Michael KauffmanChief Executive Officer, Director | 12,500 | — | — | 27,857 | — | |
| Dec 7, 2018 MForm 4 → | Dec 10, 4:28 pm EST | Sharon ShachamPresident & CSO | 12,500 | — | — | 27,857 | — | |
| Nov 26, 2018 MForm 4 → | Nov 27, 4:20 pm EST | Sharon ShachamPresident & CSO | 9,600 | — | — | 436,061 | — | |
| Nov 26, 2018 MForm 4 → | Nov 27, 4:17 pm EST | Michael KauffmanChief Executive Officer, Director | 9,600 | — | — | 436,061 | — | |
| Nov 19, 2018 MForm 4 → | Nov 21, 8:03 am EST | Sharon ShachamPresident & CSO | 400 | — | — | 445,661 | — | |
| Nov 19, 2018 MForm 4 → | Nov 21, 8:00 am EST | Michael KauffmanChief Executive Officer, Director | 400 | — | — | 445,661 | — | |
| Nov 7, 2018 MForm 4 → | Nov 9, 4:17 pm EST | Michael KauffmanChief Executive Officer, Director | 12,500 | — | — | 40,357 | — | |
| Nov 7, 2018 MForm 4 → | Nov 9, 4:16 pm EST | Sharon ShachamPresident & CSO | 12,500 | — | — | 40,357 | — | |
| Oct 18, 2018 MForm 4 → | Oct 22, 4:09 pm EDT | Sharon ShachamPresident & CSO | 10,000 | — | — | 446,061 | — | |
| Oct 18, 2018 MForm 4 → | Oct 22, 4:06 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | — | — | 446,061 | — | |
| Oct 8, 2018 MForm 4 → | Oct 9, 8:05 am EDT | Michael KauffmanChief Executive Officer, Director | 12,500 | — | — | 52,857 | — | |
| Oct 8, 2018 MForm 4 → | Oct 9, 8:00 am EDT | Sharon ShachamPresident & CSO | 12,500 | — | — | 52,857 | — | |
| Sep 18, 2018 MForm 4 → | Sep 18, 5:26 pm EDT | Sharon ShachamPresident & CSO | 10,000 | — | — | 456,061 | — | |
| Sep 18, 2018 MForm 4 → | Sep 18, 5:23 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | — | — | 456,061 | — | |
| Sep 10, 2018 MForm 4 → | Sep 11, 6:08 pm EDT | Christopher Brett PrimianoEVP, CBO, GC & Secretary | 10,000 | — | — | 113,000 | — | |
| Sep 7, 2018 MForm 4 → | Sep 10, 4:13 pm EDT | Michael KauffmanChief Executive Officer, Director | 12,500 | — | — | 1,764 | — | |
| Sep 7, 2018 MForm 4 → | Sep 10, 4:11 pm EDT | Sharon ShachamPresident & CSO | 12,500 | — | — | 1,764 | — | |
| Aug 31, 2018 AForm 4 → | Sep 4, 4:38 pm EDT | Carsten ThielDirector | 34,000 | — | — | 34,000 | — | |
| Aug 30, 2018 MForm 4 → | Sep 4, 4:10 pm EDT | Mansoor Raza MirzaDirector | 2,500 | — | — | 10,342 | — | |
| Aug 29, 2018 MForm 4 → | Aug 30, 4:38 pm EDT | Mansoor Raza MirzaDirector | 2,500 | — | — | 2,236 | — | |
| Aug 20, 2018 MForm 4 → | Aug 21, 4:14 pm EDT | Sharon ShachamPresident & CSO | 10,000 | — | — | 466,061 | — | |
| Aug 20, 2018 MForm 4 → | Aug 21, 4:11 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | — | — | 466,061 | — | |
| Aug 7, 2018 MForm 4 → | Aug 8, 4:08 pm EDT | Michael KauffmanChief Executive Officer, Director | 12,500 | — | — | 14,264 | — | |
| Aug 7, 2018 MForm 4 → | Aug 8, 4:04 pm EDT | Sharon ShachamPresident & CSO | 12,500 | — | — | 14,264 | — | |
| Jul 18, 2018 MForm 4 → | Jul 20, 4:28 pm EDT | Sharon ShachamPresident & CSO | 10,000 | — | — | 476,061 | — | |
| Jul 18, 2018 MForm 4 → | Jul 20, 4:23 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | — | — | 476,061 | — | |
| Jul 9, 2018 MForm 4 → | Jul 10, 4:10 pm EDT | Michael KauffmanChief Executive Officer, Director | 12,500 | — | — | 26,764 | — | |
| Jul 9, 2018 MForm 4 → | Jul 10, 4:09 pm EDT | Sharon ShachamPresident & CSO | 12,500 | — | — | 26,764 | — | |
| Jun 22, 2018 AForm 4 → | Jun 25, 4:44 pm EDT | Anand VaradanEVP, Chief Commercial Officer | 150,000 | — | — | 150,000 | — | |
| Jun 19, 2018 AForm 4 → | Jun 20, 4:25 pm EDT | Garen G BohlinDirector | 17,000 | — | — | 17,000 | — | |
| Jun 19, 2018 AForm 4 → | Jun 20, 4:21 pm EDT | Mikael DolstenDirector | 17,000 | — | — | 17,000 | — | |
| Jun 19, 2018 AForm 4 → | Jun 20, 4:19 pm EDT | J. Scott GarlandDirector | 17,000 | — | — | 17,000 | — | |
| Jun 19, 2018 AForm 4 → | Jun 20, 4:15 pm EDT | Barry E GreeneDirector | 17,000 | — | — | 17,000 | — | |
| Jun 19, 2018 AForm 4 → | Jun 20, 4:11 pm EDT | Mansoor Raza MirzaDirector | 17,000 | — | — | 17,000 | — | |
| Jun 19, 2018 AForm 4 → | Jun 20, 4:08 pm EDT | Deepika PakianathanDirector | 17,000 | — | — | 17,000 | — | |
| Jun 18, 2018 MForm 4 → | Jun 19, 4:06 pm EDT | Sharon ShachamPresident & CSO | 10,000 | — | — | 5,757 | — | |
| Jun 18, 2018 MForm 4 → | Jun 19, 4:05 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | — | — | 5,757 | — | |
| Jun 7, 2018 MForm 4 → | Jun 11, 4:17 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | — | — | 7,553 | — | |
| Jun 7, 2018 MForm 4 → | Jun 11, 4:11 pm EDT | Sharon ShachamPresident & CSO | 10,000 | — | — | 7,553 | — | |
| May 18, 2018 MForm 4 → | May 21, 4:28 pm EDT | Sharon ShachamPresident & CSO | 10,000 | — | — | 15,757 | — | |
| May 18, 2018 MForm 4 → | May 21, 4:26 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | — | — | 15,757 | — | |
| May 10, 2018 MForm 4 → | May 11, 4:08 pm EDT | Mansoor Raza MirzaDirector | 2,000 | — | — | 4,736 | — | |
| May 7, 2018 MForm 4 → | May 8, 4:21 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | — | — | 9,697 | — | |
| May 7, 2018 MForm 4 → | May 8, 4:19 pm EDT | Sharon ShachamPresident & CSO | 10,000 | — | — | 9,697 | — | |
| Apr 18, 2018 MForm 4 → | Apr 20, 4:07 pm EDT | Sharon ShachamPresident & CSO | 10,000 | — | — | 18,181 | — | |
| Apr 18, 2018 MForm 4 → | Apr 20, 4:06 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | — | — | 18,181 | — | |
| Apr 9, 2018 MForm 4 → | Apr 10, 4:20 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | — | — | 19,697 | — | |
| Apr 9, 2018 MForm 4 → | Apr 10, 4:17 pm EDT | Sharon ShachamPresident & CSO | 10,000 | — | — | 19,697 | — | |
| Mar 19, 2018 MForm 4 → | Mar 20, 4:36 pm EDT | Sharon ShachamPresident & CSO | 10,000 | — | — | 2,424 | — | |
| Mar 19, 2018 MForm 4 → | Mar 20, 4:34 pm EDT | Michael KauffmanChief Executive Officer, Director | 10,000 | — | — | 2,424 | — | |
| Mar 12, 2018 MForm 4 → | Mar 14, 5:08 pm EDT | Mansoor Raza MirzaDirector | 2,500 | — | — | 675 | — | |
| Mar 7, 2018 MForm 4 → | Mar 8, 5:57 pm EST | Michael KauffmanChief Executive Officer, Director | 10,000 | — | — | 29,697 | — | |
| Mar 7, 2018 MForm 4 → | Mar 8, 5:54 pm EST | Sharon ShachamPresident & CSO | 10,000 | — | — | 29,697 | — | |
| Mar 5, 2018 MForm 4 → | Mar 6, 4:56 pm EST | Mansoor Raza MirzaDirector | 2,500 | — | — | 3,175 | — | |
| Feb 20, 2018 MForm 4 → | Feb 22, 4:17 pm EST | Sharon ShachamPresident & CSO | 10,000 | — | — | 12,424 | — | |
| Feb 20, 2018 MForm 4 → | Feb 22, 4:15 pm EST | Michael KauffmanChief Executive Officer, Director | 10,000 | — | — | 12,424 | — | |
| Feb 8, 2018 MForm 4 → | Feb 12, 4:32 pm EST | Mansoor Raza MirzaDirector | 1,500 | — | — | 5,675 | — | |
| Feb 7, 2018 MForm 4 → | Feb 8, 4:11 pm EST | Mansoor Raza MirzaDirector | 1,500 | — | — | 7,175 | — | |
| Feb 7, 2018 MForm 4 → | Feb 8, 4:08 pm EST | Michael KauffmanChief Executive Officer, Director | 10,000 | — | — | 9,394 | — | |
| Feb 7, 2018 MForm 4 → | Feb 8, 4:07 pm EST | Sharon ShachamPresident & CSO | 10,000 | — | — | 9,394 | — | |
| Jan 24, 2018 AForm 4 → | Jan 25, 4:31 pm EST | Ran FrenkelChief Dev Operations Officer | 60,000 | — | — | 60,000 | — | |
| Jan 24, 2018 AForm 4 → | Jan 25, 4:30 pm EST | Michael FalveyEVP, CFO & Treasurer | 95,000 | — | — | 95,000 | — | |
| Jan 24, 2018 AForm 4 → | Jan 25, 4:29 pm EST | Christopher Brett PrimianoEVP, CBO, GC & Secretary | 125,000 | — | — | 125,000 | — | |
| Jan 24, 2018 AForm 4 → | Jan 25, 4:28 pm EST | Sharon ShachamPresident & CSO | 400,000 | — | — | 200,000 | — | |
| Jan 24, 2018 AForm 4 → | Jan 25, 4:27 pm EST | Michael KauffmanChief Executive Officer, Director | 400,000 | — | — | 200,000 | — | |
| Jan 18, 2018 MForm 4 → | Jan 22, 4:08 pm EST | Sharon ShachamPresident & CSO | 10,000 | — | — | 22,424 | — | |
| Jan 18, 2018 MForm 4 → | Jan 22, 4:05 pm EST | Michael KauffmanChief Executive Officer, Director | 10,000 | — | — | 22,424 | — | |
| Jan 8, 2018 MForm 4 → | Jan 9, 4:10 pm EST | Michael KauffmanChief Executive Officer, Director | 10,000 | — | — | 19,394 | — | |
| Jan 8, 2018 MForm 4 → | Jan 9, 4:08 pm EST | Sharon ShachamPresident & CSO | 10,000 | — | — | 19,394 | — | |
| Dec 18, 2017 MForm 4 → | Dec 20, 4:21 pm EST | Sharon ShachamPresident & CSO | 10,000 | — | — | 32,424 | — | |
| Dec 18, 2017 MForm 4 → | Dec 20, 4:19 pm EST | Michael KauffmanChief Executive Officer, Director | 10,000 | — | — | 32,424 | — | |
| Dec 12, 2017 MForm 4 → | Dec 13, 4:04 pm EST | Christopher Brett PrimianoSVP, OPS, BUS DEV, GC & SEC | 17,000 | — | — | 23,000 | — | |
| Dec 7, 2017 MForm 4 → | Dec 8, 4:07 pm EST | Michael KauffmanChief Executive Officer, Director | 10,000 | — | — | 29,394 | — | |
| Dec 7, 2017 MForm 4 → | Dec 8, 4:05 pm EST | Sharon ShachamPresident & CSO | 10,000 | — | — | 29,394 | — | |
| Nov 5, 2017 MForm 4 → | Nov 6, 4:09 pm EST | Ran FrenkelChief Dev Operations Officer | 15,000 | — | — | 0 | — | |
| Nov 5, 2017 MForm 4 → | Nov 6, 4:05 pm EST | Christopher Brett PrimianoSVP, OPS, BUS DEV, GC & SEC | 15,000 | — | — | 0 | — | |
| Oct 2, 2017 MForm 4 → | Oct 4, 4:08 pm EDT | Mansoor Raza MirzaDirector | 2,000 | — | — | 1,099 | — | |
| Sep 15, 2017 MForm 4 → | Sep 18, 4:11 pm EDT | Mansoor Raza MirzaDirector | 2,882 | — | — | 3,099 | — | |
| Sep 11, 2017 MForm 4 → | Sep 13, 4:13 pm EDT | Mansoor Raza MirzaDirector | 118 | — | — | 5,981 | — | |
| Sep 11, 2017 AForm 4 → | Sep 13, 4:09 pm EDT | Michael FalveyEVP, CFO & Treasurer | 125,000 | — | — | 125,000 | — | |
| Jun 15, 2017 AForm 4 → | Jun 16, 4:52 pm EDT | Kenneth E WegDirector | 17,000 | — | — | 17,000 | — | |
| Jun 15, 2017 AForm 4 → | Jun 16, 4:50 pm EDT | Deepika PakianathanDirector | 17,000 | — | — | 17,000 | — | |
| Jun 15, 2017 AForm 4 → | Jun 16, 4:48 pm EDT | Mansoor Raza MirzaDirector | 17,000 | — | — | 17,000 | — | |
| Jun 15, 2017 AForm 4 → | Jun 16, 4:47 pm EDT | Barry E GreeneDirector | 17,000 | — | — | 17,000 | — | |
| Jun 15, 2017 AForm 4 → | Jun 16, 4:45 pm EDT | J. Scott GarlandDirector | 17,000 | — | — | 17,000 | — | |
| Jun 15, 2017 AForm 4 → | Jun 16, 4:41 pm EDT | Mikael DolstenDirector | 17,000 | — | — | 17,000 | — | |
| Jun 15, 2017 AForm 4 → | Jun 16, 4:38 pm EDT | Garen G BohlinDirector | 17,000 | — | — | 17,000 | — | |
| Jan 20, 2017 AForm 4 → | Jan 24, 5:39 pm EST | Ran FrenkelChief Dev Operations Officer | 100,000 | — | — | 100,000 | — | |
| Jan 20, 2017 AForm 4 → | Jan 24, 5:38 pm EST | Christopher Brett PrimianoSVP, OPS, BUS DEV, GC & SEC | 118,000 | — | — | 118,000 | — | |
| Jan 20, 2017 AForm 4 → | Jan 24, 5:36 pm EST | Justin A RenzEVP, CFO & Treasurer | 100,000 | — | — | 100,000 | — | |
| Jan 20, 2017 AForm 4 → | Jan 24, 5:34 pm EST | Sharon ShachamPresident & CSO | 500,000 | — | — | 250,000 | — |