Form4insider filings, from the source

Insider holders · CIK 0001701108

Spero Therapeutics, Inc. · SPRO

Every insider with a reported Table I holding at this company, ranked by their last-reported share count. A balance is only as fresh as its filing — the report date sits next to every row on purpose. ← Back to activity

InsiderDirect sharesIndirect sharesTotal reportedLast report (ET)From
Jean Francois FormelaDirector—2,408,1282,408,128Nov 7, 2017 · 4:08 pm ESTForm 4
GLAXOSMITHKLINE PLC10% Owner—1,934,0061,934,006Jul 17, 2018 · 5:01 pm EDTForm 4
Vikas GoyalDirector—1,854,0061,854,006Nov 7, 2017 · 4:06 pm ESTForm 4
Casper BreumDirector—1,091,7741,091,774Nov 7, 2017 · 4:05 pm ESTForm 4
Debra ZackChief Medical Officer162,311—162,311Aug 6, 2026 · 6:49 pm EDTForm 4
Ankit MahadeviaSee Remarks65,81765,817131,634Jul 6, 2018 · 9:41 pm EDTForm 4
Milind DeshpandeDirector101,454—101,454Jun 25, 2026 · 7:26 pm EDTForm 4
Kathleen TregoningDirector85,000—85,000Jun 25, 2026 · 7:17 pm EDTForm 4
Cynthia SmithDirector85,000—85,000Jun 25, 2026 · 7:14 pm EDTForm 4
Scott Thomas JacksonDirector85,000—85,000Jun 25, 2026 · 6:57 pm EDTForm 4
Patrick V.J.J. VinkDirector85,000—85,000Jun 25, 2026 · 7:12 pm EDTForm 4
John C Pottage Jr.Director85,000—85,000Jun 25, 2026 · 6:55 pm EDTForm 4
Frank E ThomasDirector85,000—85,000Jun 25, 2026 · 6:59 pm EDTForm 4
Atlas Venture Fund IX, L.P.10% Owner42,781—42,781Nov 1, 2017 · 7:50 pm EDTForm 3
Atlas Venture Associates IX, L.P.10% Owner42,781—42,781Nov 1, 2017 · 7:50 pm EDTForm 3
Atlas Venture Associates IX, LLC10% Owner42,781—42,781Nov 1, 2017 · 7:50 pm EDTForm 3
Joel SendekChief Financial Officer15,18110,18125,362Jul 6, 2018 · 9:44 pm EDTForm 4
Cristina LarkinChief Operating Officer1,500—1,500Jul 6, 2018 · 9:45 pm EDTForm 4

Balances come from each insider’s most recent filing that reports a Table I holding; an insider who left the company years ago still appears with their last-known figure and its date. Indirect totals collapse multiple vehicles (trusts, LLCs) into one number — open the filing for the breakdown. Shares as filed, not split-adjusted.