SEC Form 4 · accession 0000874015-26-000218
IONIS PHARMACEUTICALS INC · IONS
Statement of changes in beneficial ownership, as filed. Original on EDGAR ↗
Reporting owner
Joseph Baroldi
Officer — EVP, Chief Business Officer
Period of report
Jun 26, 2026
Accepted (ET)
Jun 30, 2026 · 5:48 pm EDT
Rule 10b5-1 plan
yes — trade under a plan
Issuer CIK
0000874015
Table I — non-derivative securities
| Security | Date | Code | Shares | Price | A/D | Owned after | D/I | Nature of ownership |
|---|---|---|---|---|---|---|---|---|
| Common Stock | Jun 26, 2026 | M | 3,866 | $56.78 | A | 8,535 | I | by Spouse |
| Common Stock | Jun 26, 2026 | M | 1,769 | $32.60 | A | 10,304 | I | by Spouse |
| Common StockF1,F2 | Jun 26, 2026 | S | 5,635 | $80.1595 | D | 4,669 | I | by Spouse |
| Common Stock | holding | — | — | — | 48,522 | D |
Table II — derivative securities
| Security | Conv. / exercise price | Date | Code | Shares | A/D | Exercisable | Expires | Underlying | Underlying shares | Owned after | D/I |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Non-Qualified Stock Option (right to buy) | $32.60 | Jun 26, 2026 | M | 1,769 | D | Jan 3, 2023 | Jan 2, 2032 | Common Stock | 1,769 | 0 | I |
| Non-Qualified Stock Option (right to buy) | $56.78 | Jun 26, 2026 | M | 3,866 | D | Jan 4, 2022 | Jan 3, 2028 | Common Stock | 3,866 | 0 | I |
Explanation of responses
- F1Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting persons spouse on November 25, 2025.
- F2The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $80.00 to $80.52 inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc. any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) on this Form 4.