SEC Form 4 · accession 0000874015-26-000188
IONIS PHARMACEUTICALS INC · IONS
Statement of changes in beneficial ownership, as filed. Original on EDGAR ↗
Reporting owner
Spencer R Berthelsen
Director
Period of report
Jun 1, 2026
Accepted (ET)
Jun 3, 2026 · 5:34 pm EDT
Rule 10b5-1 plan
yes — trade under a plan
Issuer CIK
0000874015
Table I — non-derivative securities
| Security | Date | Code | Shares | Price | A/D | Owned after | D/I | Nature of ownership |
|---|---|---|---|---|---|---|---|---|
| Common Stock | Jun 1, 2026 | M | 8,000 | $24.42 | A | 164,013 | D | |
| Common StockF1 | Jun 1, 2026 | S | 8,000 | $75.67 | D | 156,013 | D | |
| Common StockF2 | holding | — | — | — | 70 | I | by Daughter |
Table II — derivative securities
| Security | Conv. / exercise price | Date | Code | Shares | A/D | Exercisable | Expires | Underlying | Underlying shares | Owned after | D/I |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Non-Qualified Stock Option (right to buy) | $24.42 | Jun 1, 2026 | M | 8,000 | D | Jul 1, 2017 | Jun 30, 2026 | Common Stock | 8,000 | 8,000 | D |
Explanation of responses
- F1Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on September 12, 2025.
- F2The reporting person disclaims beneficial ownership of all securities held by his daughter, and this report should not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 or for any other purpose.