Security	Date	Code	Shares	Price	A/D	Owned after	D/I	Nature of ownership
Common Stock^F1,F2	Aug 10, 2026	C	4,975,543	—	A	4,975,543	I	By 5AM Ventures VI, L.P.
Common Stock^F1,F3	Aug 10, 2026	C	2,350,419	—	A	2,350,419	I	By 5AM Opportunities II, L.P.

Table II — derivative securities

Security	Conv. / exercise price	Date	Code	Shares	A/D	Exercisable	Expires	Underlying	Underlying shares	D/I
Series A Preferred Stock^F2,F1	—	Aug 10, 2026	C	3,152,305	D	—	—	Common Stock	3,152,305	I
Series A-2 Preferred Stock^F2,F1	—	Aug 10, 2026	C	1,823,238	D	—	—	Common Stock	1,823,238	I
Series A-2 Preferred Stock^F3,F1	—	Aug 10, 2026	C	866,018	D	—	—	Common Stock	866,018	I
Series B Preferred Stock^F3,F1	—	Aug 10, 2026	C	1,484,401	D	—	—	Common Stock	1,484,401	I

Explanation of responses

F1Each share of Series A Preferred Stock, Series A-2 Preferred Stock and Series B Preferred Stock automatically converted into Common Stock immediately prior to the closing of the Issuer's initial public offering for no additional consideration, on a one-for-one basis. The Series A Preferred Stock, Series A-2 Preferred Stock and Series B Preferred Stock had no expiration date.
F2The securities are directly held by 5AM Ventures VI, L.P. ("Ventures VI"). 5AM Partners VI, LLC ("Partners VI") is the sole general partner of Ventures VI. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Partners VI and may be deemed to have shared voting and investment power over the securities beneficially owned by Ventures VI. Each of Partners VI, Dr. Parmar, and Mr. Schwab disclaims beneficial ownership of such securities except to the extent of its or his respective pecuniary interest therein.
F3The securities are directly held by 5AM Opportunities II, L.P. ("Opportunities II"). 5AM Opportunities II (GP), LLC ("Opportunities II GP") is the general partner of Opportunities II and may be deemed to have sole investment and voting power over the securities held by Opportunities II. Dr. Kush Parmar and Andrew J. Schwab are the managing members of Opportunities II GP and may be deemed to have shared voting and investment power over the securities beneficially owned by Opportunities II. Each of Opportunities II GP, Dr. Parmar, and Mr. Schwab disclaims beneficial ownership of such securities except to the extent of its or his respective pecuniary interest therein.