SEC Form 4 · accession 0001193125-26-291051
Septerna, Inc. · SEPN
Statement of changes in beneficial ownership, as filed. Original on EDGAR ↗
Reporting owner
Jake Simson
Director
Period of report
Jun 26, 2026
Accepted (ET)
Jun 30, 2026 · 7:00 pm EDT
Rule 10b5-1 plan
box not checked
Issuer CIK
0001984086
Table I — non-derivative securities
No Table I lines on this filing.
Table II — derivative securities
| Security | Conv. / exercise price | Date | Code | Shares | A/D | Exercisable | Expires | Underlying | Underlying shares | Owned after | D/I |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Stock Option (Right to Buy)F2,F1 | $37.34 | Jun 26, 2026 | A | 15,000 | A | — | Jun 25, 2036 | Common Stock | 15,000 | 15,000 | D |
Explanation of responses
- F1The shares underlying the stock option vest in full upon the earlier of (i) June 26, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service to the Issuer through such vesting date.
- F2Under the Reporting Person's arrangement with RA Capital Management, L.P. (the "Adviser"), the Reporting Person holds the option for the benefit of the R.A. Capital Healthcare Fund, L.P. (the "Fund") and R.A. Capital Nexus Fund III, L.P. (the "Nexus Fund III"). The Reporting Person is obligated to turn over to the Adviser any net cash or stock received upon exercise of the option, which will offset advisory fees owed by the Fund and the Nexus Fund III to the Adviser. The Reporting Person therefore disclaims beneficial ownership of the option and underlying common stock.
Remarks
Exhibit 24.2 - Substitute Power of Attorney