Form4insider filings, from the source

SEC Form 4 · accession 0001193125-26-315240

Structure Therapeutics Inc. · GPCR

Statement of changes in beneficial ownership, as filed. Original on EDGAR ↗

Reporting owner
FMR LLC
10% Owner · Other
Period of report
Jul 22, 2026
Accepted (ET)
Jul 24, 2026 · 9:11 am EDT
Rule 10b5-1 plan
box not checked
Issuer CIK
0001888886

Table I — non-derivative securities

SecurityDateCodeSharesPriceA/DOwned afterD/INature of ownership
Ordinary Sharesholding———20,502IF-Prime Capital Partners Life Sciences Advisors Fund VI LP
Ordinary Sharesholding———241,275IF-Prime Capital Partners Life Sciences Fund VI LP

Table II — derivative securities

SecurityConv. / exercise priceDateCodeSharesA/DExercisableExpiresUnderlyingUnderlying sharesOwned afterD/I
American Depositary SharesF2,F1—Jul 22, 2026S1,367D——Ordinary Shares4,1011,369I
American Depositary SharesF2,F1—Jul 22, 2026S16,085D——Ordinary Shares48,25516,086I
American Depositary SharesF1—holding—————Ordinary Shares4,546,6741,515,558I

Explanation of responses

Remarks

Remark 1: Abigail P. Johnson is a Director, the Chairman and the Chief Executive Officer of FMR LLC. Members of the Johnson family, including Abigail P. Johnson, are the predominant owners, directly or through trusts, of Series B voting common shares of FMR LLC, representing 49% of the voting power of FMR LLC. The Johnson family group and all other Series B shareholders have entered into a shareholders' voting agreement under which all Series B voting common shares will be voted in accordance with the majority vote of Series B voting common shares. Accordingly, through their ownership of voting common shares and the execution of the shareholders' voting agreement, members of the Johnson family may be deemed, under the Investment Company Act of 1940, to form a controlling group with respect to FMR LLC. The address of Abigail P. Johnson is c/o FMR LLC, 245 Summer Street, Boston, MA 02110. Remark 2: The filing of this statement shall not be deemed to be an admission that, for purposes of Section 16 of the Securities Exchange Act of 1934 or otherwise, the undersigned are the beneficial owners of any securities reported herein. Remark 3: F-Prime Capital Partners Life Sciences Advisors Fund VI LP (FPCPLSA) is the general partner of F-Prime Capital Partners Life Sciences Fund VI LP. FPCPLSA is solely managed by Impresa Management LLC, the managing member of its general partner and its investment manager. Impresa Management LLC is owned, directly or indirectly, by various shareholders and employees of FMR LLC, including certain members of the Johnson family.