Security	Date	Code	Shares	Price	A/D	Owned after	D/I	Nature of ownership
Common Stock^F1,F3	Dec 8, 2017	S$0	51,896	—	D	137,605	I	By Radius Venture Partners III (Ohio), L.P.
Common Stock^F1,F4	Dec 8, 2017	S$0	413,210	—	D	1,095,654	I	By Radius Venture Partners III QP, L.P.
Common Stock^F1,F5	Dec 8, 2017	S$0	37,984	—	D	100,477	I	By Radius Venture Partners III, L.P.
Common Stock^F2,F3	Dec 11, 2017	S$0	15,888	—	D	121,717	I	By Radius Venture Partners III (Ohio), L.P.
Common Stock^F2,F4	Dec 11, 2017	S$0	126,510	—	D	969,144	I	By Radius Venture Partners III QP, L.P.
Common Stock^F2,F5	Dec 11, 2017	S$0	11,602	—	D	88,875	I	By Radius Venture Partners III, L.P.

Table II — derivative securities

No Table II lines on this filing.

Explanation of responses

F1Represents shares of the issuer's common stock sold in an underwritten public offering completed on December 8, 2017 at a public offering price of $25.85 per common share, after deducting underwriting discounts and commissions of $1.65 per share.
F2Represents shares of the issuer's common stock sold upon the exercise of the underwriters' over-allotment option in an underwritten public offering completed on December 11, 2017 at a public offering price of $25.85 per common share, after deducting underwriting discounts and commissions of $1.65 per share.
F3These securities are held directly by Radius Venture Partners III (Ohio), L.P. and indirectly by Radius Venture Partners III, LLC, the general partner of Radius Venture Partners III (Ohio), L.P., Jordan S. Davis, managing member of Radius Venture Partners III, LLC, and Daniel C. Lubin, managing member of Radius Venture Partners III, LLC. Mr. Lubin and Mr. Davis share voting and dispositive power with respect to the shares held by Radius Venture Partners III (Ohio), L.P. Mr. Lubin is a director of the Issuer and files separate Section 16 reports. Each of Radius Venture Partners III, LLC, Mr. Davis, and Mr. Lubin may be deemed to beneficially own such securities, and disclaims such beneficial ownership except to the extent of its or his pecuniary interest therein.
F4These securities are held directly by Radius Venture Partners III QP, L.P and indirectly by Radius Venture Partners III, LLC, the general partner of Radius Venture Partners III QP, L.P., Jordan S. Davis, managing member of Radius Venture Partners III, LLC, and Daniel C. Lubin, managing member of Radius Venture Partners III, LLC. Mr. Lubin and Mr. Davis share voting and dispositive power with respect to the shares held by Radius Venture Partners III QP, L.P. Mr. Lubin is a director of the Issuer and files separate Section 16 reports. Each of Radius Venture Partners III, LLC, Mr. Davis, and Mr. Lubin may be deemed to beneficially own such securities, and disclaims such beneficial ownership except to the extent of its or his pecuniary interest therein.
F5These securities are held directly by Radius Venture Partners III, L.P., and indirectly by Radius Venture Partners III, LLC, the general partner of Radius Venture Partners III, L.P., Jordan S. Davis, managing member of Radius Venture Partners III, LLC, and Daniel C. Lubin, managing member of Radius Venture Partners III, LLC. Mr. Lubin and Mr. Davis share voting and dispositive power with respect to the shares held by Radius Venture Partners III, L.P. Mr. Lubin is a director of the Issuer and files separate Section 16 reports. Each of Radius Venture Partners III, LLC, Mr. Davis, and Mr. Lubin may be deemed to beneficially own such securities, and disclaims such beneficial ownership except to the extent of its or his pecuniary interest therein.