SEC Form 4 · accession 0001042047-26-000019
BeOne Medicines Ltd. · ONC
Statement of changes in beneficial ownership, as filed. Original on EDGAR ↗
Reporting owner
John Oyler
Officer — Chief Executive Officer · Director
Period of report
Aug 10, 2026
Accepted (ET)
Aug 12, 2026 · 5:53 pm EDT
Rule 10b5-1 plan
yes — trade under a plan
Issuer CIK
0001651308
Table I — non-derivative securities
| Security | Date | Code | Shares | Price | A/D | Owned after | D/I | Nature of ownership |
|---|---|---|---|---|---|---|---|---|
| American Depositary SharesF6 | Aug 10, 2026 | S | 67 | $350.00 | D | 240,743 | D | |
| American Depositary SharesF6,F8 | Aug 10, 2026 | S | 2,813 | $351.7962 | D | 237,930 | D | |
| American Depositary SharesF6,F9 | Aug 10, 2026 | S | 3,673 | $353.3191 | D | 234,257 | D | |
| American Depositary SharesF6,F10 | Aug 10, 2026 | S | 6,717 | $354.7757 | D | 227,540 | D | |
| American Depositary SharesF6,F11 | Aug 10, 2026 | S | 3,476 | $355.6563 | D | 224,064 | D | |
| American Depositary SharesF6,F12 | Aug 10, 2026 | S | 12,418 | $356.618 | D | 211,646 | D | |
| American Depositary SharesF6,F13 | Aug 10, 2026 | S | 15,869 | $357.6699 | D | 195,777 | D | |
| American Depositary SharesF6,F14 | Aug 10, 2026 | S | 45,044 | $358.6954 | D | 150,733 | D | |
| American Depositary SharesF6,F15 | Aug 10, 2026 | S | 21,254 | $359.5006 | D | 129,479 | D | |
| American Depositary SharesF6,F16 | Aug 10, 2026 | S | 3,680 | $360.6332 | D | 125,799 | D | |
| American Depositary SharesF6,F17 | Aug 11, 2026 | S | 13,695 | $359.3168 | D | 112,104 | D | |
| American Depositary SharesF6,F18 | Aug 11, 2026 | S | 8,081 | $360.3328 | D | 104,023 | D | |
| American Depositary SharesF6,F19 | Aug 11, 2026 | S | 14,569 | $361.4708 | D | 89,454 | D | |
| American Depositary SharesF6,F20 | Aug 11, 2026 | S | 11,568 | $362.3399 | D | 77,886 | D | |
| American Depositary SharesF6,F21 | Aug 11, 2026 | S | 13,403 | $363.4518 | D | 64,483 | D | |
| American Depositary SharesF6,F22 | Aug 11, 2026 | S | 5,211 | $364.3144 | D | 59,272 | D | |
| American Depositary SharesF6,F23 | Aug 11, 2026 | S | 3,176 | $365.2642 | D | 56,096 | D | |
| American Depositary SharesF6,F24 | Aug 11, 2026 | S | 1,200 | $366.312 | D | 54,896 | D | |
| American Depositary SharesF6 | Aug 11, 2026 | S | 4 | $367.00 | D | 54,892 | D | |
| American Depositary SharesF6,F25 | Aug 12, 2026 | S | 1,980 | $354.7072 | D | 52,912 | D | |
| American Depositary SharesF6,F26 | Aug 12, 2026 | S | 2,515 | $356.4318 | D | 50,397 | D | |
| American Depositary SharesF6,F27 | Aug 12, 2026 | S | 15,396 | $357.6349 | D | 35,001 | D | |
| American Depositary SharesF6,F28 | Aug 12, 2026 | S | 20,899 | $358.4118 | D | 14,102 | D | |
| American Depositary SharesF6,F29 | Aug 12, 2026 | S | 14,102 | $359.1159 | D | 0 | D | |
| Ordinary Shares | holding | — | — | — | 1,330,988 | D | ||
| Ordinary SharesF1 | holding | — | — | — | 481,533 | I | See Footnote | |
| Ordinary SharesF2 | holding | — | — | — | 7,699,158 | I | See Footnote | |
| Ordinary SharesF3 | holding | — | — | — | 28,204,115 | I | See Footnote | |
| Ordinary SharesF4 | holding | — | — | — | 9,545,000 | I | See Footnote | |
| Ordinary SharesF5 | holding | — | — | — | 102,188 | I | See Footnote |
Table II — derivative securities
No Table II lines on this filing.
Explanation of responses
- F1These securities are held by the P&O Trust, the beneficiaries of which include the Reporting Person's child and others, for which the Reporting Person disclaims beneficial ownership.
- F10The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $354.03 to $355.01, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F11The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $355.08 to $356.05, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F12The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $356.08 to $357.06, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F13The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $357.08 to $358.07, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F14The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $358.08 to $359.07, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F15The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $359.08 to $360.00, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F16The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $360.25 to $361.14, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F17The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $358.90 to $359.89, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F18The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $359.92 to $360.91, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F19The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $360.92 to $361.91, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F2These securities are held in a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership.
- F20The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $361.94 to $362.74, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F21The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $362.95 to $363.94, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F22The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $363.95 to $364.90, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F23The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $365.00 to $365.90, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F24The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $366.00 to $366.99, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F25The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $354.35 to $355.05, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F26The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $355.92 to $356.91, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F27The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $356.95 to $357.94, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F28The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $357.95 to $358.94, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F29The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $358.95 to $359.68, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F3These securities are held by Oyler Investment LLC, of which 99% of the limited liability company interests are owned by a grantor retain annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership.
- F4These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account.
- F5These securities are held by The John Oyler Legacy Trust for the benefit of the Reporting Person's child, for which the Reporting Person disclaims beneficial ownership.
- F6Each American Depositary Share represents 13 Ordinary Shares.
- F7The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 10, 2026.
- F8The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $351.01 to $351.99, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.
- F9The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $353.00 to $353.99, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.