SEC Form 4 · accession 0001214659-26-011832
Twist Bioscience Corp · TWST
Statement of changes in beneficial ownership, as filed. Original on EDGAR ↗
Reporting owner
Emily M. Leproust
Officer — Chief Executive Officer · Director
Period of report
Sep 17, 2026
Accepted (ET)
Sep 21, 2026 · 4:05 pm EDT
Rule 10b5-1 plan
yes — trade under a plan
Issuer CIK
0001581280
Table I — non-derivative securities
| Security | Date | Code | Shares | Price | A/D | Owned after | D/I | Nature of ownership |
|---|---|---|---|---|---|---|---|---|
| Common Stock | Sep 17, 2026 | M | 133,269 | $26.66 | A | 901,696 | D | |
| Common Stock | Sep 17, 2026 | M | 75,439 | $8.82 | A | 977,135 | D | |
| Common StockF2 | Sep 17, 2026 | S | 2,440 | $151.4613 | D | 974,695 | D | |
| Common StockF3 | Sep 17, 2026 | S | 6,644 | $152.2112 | D | 968,051 | D | |
| Common StockF4 | Sep 17, 2026 | S | 3,399 | $153.4031 | D | 964,652 | D | |
| Common StockF5 | Sep 17, 2026 | S | 4,175 | $154.1703 | D | 960,477 | D | |
| Common StockF6 | Sep 17, 2026 | S | 13,378 | $155.4568 | D | 947,099 | D | |
| Common StockF7 | Sep 17, 2026 | S | 9,097 | $156.4674 | D | 938,002 | D | |
| Common StockF8 | Sep 17, 2026 | S | 32,260 | $157.486 | D | 905,742 | D | |
| Common StockF9 | Sep 17, 2026 | S | 232,173 | $158.0876 | D | 673,569 | D | |
| Common StockF10 | Sep 17, 2026 | S | 23,884 | $159.5315 | D | 649,685 | D | |
| Common StockF11 | Sep 17, 2026 | S | 14,493 | $160.4392 | D | 635,192 | D | |
| Common StockF12 | Sep 17, 2026 | S | 11,169 | $161.493 | D | 624,023 | D | |
| Common StockF13 | Sep 17, 2026 | S | 2,565 | $162.3136 | D | 621,458 | D | |
| Common StockF14 | Sep 17, 2026 | S | 869 | $163.3926 | D | 620,589 | D |
Table II — derivative securities
| Security | Conv. / exercise price | Date | Code | Shares | A/D | Exercisable | Expires | Underlying | Underlying shares | Owned after | D/I |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Employee Stock Option (right to buy)F18 | $8.82 | Sep 17, 2026 | M | 75,439 | D | — | Sep 28, 2027 | Common Stock | 75,439 | 0 | D |
| Employee Stock Option (right to buy)F19 | $26.66 | Sep 17, 2026 | M | 133,269 | D | — | Nov 18, 2028 | Common Stock | 133,269 | 0 | D |
| Employee Stock Option (right to buy)F15 | $5.95 | holding | — | — | — | — | Sep 28, 2025 | Common Stock | 0 | 0 | D |
| Employee Stock Option (right to buy)F16 | $23.33 | holding | — | — | — | — | Oct 23, 2029 | Common Stock | 131,290 | 131,290 | D |
| Employee Stock Option (right to buy)F17 | $67.85 | holding | — | — | — | Dec 19, 2022 | Aug 31, 2030 | Common Stock | 64,950 | 64,950 | D |
Explanation of responses
- F1The transactions reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person on June 15, 2026.
- F10Represents the weighted average sales price per share. The shares sold at prices ranging from $158.99 to $159.99 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.
- F11Represents the weighted average sales price per share. The shares sold at prices ranging from $160.00 to $160.99 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.
- F12Represents the weighted average sales price per share. The shares sold at prices ranging from $161.00 to $161.97 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.
- F13Represents the weighted average sales price per share. The shares sold at prices ranging from $162.02 to $163 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.
- F14Represents the weighted average sales price per share. The shares sold at prices ranging from $163.03 to $163.6 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.
- F15The option is immediately exercisable. 25% of the shares subject to the option vested on September 1, 2016 and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
- F1625% of the shares subject to the option vested on October 24, 2020, and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
- F17Represents performance stock options granted to the reporting person on September 1, 2020, that vested and became exercisable on December 19, 2022 as a result of the reporting person having met the applicable performance criteria.
- F18The option is immediately exercisable. 10% of the shares subject to the option vested on September 28, 2017, 15% of the shares subject to the option vested on September 28, 2018, and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
- F19The option is immediately exercisable. 20% of the shares subject to the option vested and became exercisable on October 31, 2019 and 1/60th of the shares subject to the option vested and became exercisable on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.
- F2Represents the weighted average sales price per share. The shares sold at prices ranging from $150.77 to 151.77 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.
- F3Represents the weighted average sales price per share. The shares sold at prices ranging from $151.78 to $152.71 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.
- F4Represents the weighted average sales price per share. The shares sold at prices ranging from $152.87 to $153.85 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.
- F5Represents the weighted average sales price per share. The shares sold at prices ranging from $153.88 to $154.84 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.
- F6Represents the weighted average sales price per share. The shares sold at prices ranging from $154.9 to $155.9 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.
- F7Represents the weighted average sales price per share. The shares sold at prices ranging from $155.92 to $156.91 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.
- F8Represents the weighted average sales price per share. The shares sold at prices ranging from $156.96 to $157.96 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.
- F9Represents the weighted average sales price per share. The shares sold at prices ranging from $157.97 to $158.96 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.