SEC Form 4 · accession 0001736026-26-000002

SERA PROGNOSTICS, INC. · SERA

Statement of changes in beneficial ownership, as filed. Original on EDGAR ↗

Reporting owner

Jane F Barlow

Director

Period of report

Jul 10, 2026

Accepted (ET)

Jul 14, 2026 · 6:41 pm EDT

Rule 10b5-1 plan

box not checked

Issuer CIK

0001534969

Table I — non-derivative securities

Security	Date	Code	Shares	Price	A/D	Owned after	D/I	Nature of ownership
Class A Common Stock^F1	Jul 10, 2026	A	22,426	$0.00	A	45,139	D
Class A Common Stock^F2	Jul 10, 2026	A	1,949	$0.00	A	47,088	D

Table II — derivative securities

Security	Conv. / exercise price	Date	Code	Shares	A/D	Exercisable	Expires	Underlying	Underlying shares	Owned after	D/I
Stock Option (right to buy)^F3	$1.97	Jul 10, 2026	A	34,494	A	—	Jul 10, 2036	Class A Common Stock	34,494	34,494	D
Stock Option (right to buy)^F4	$1.97	Jul 10, 2026	A	2,998	A	—	Jul 10, 2036	Class A Common Stock	2,998	2,998	D

Explanation of responses

F1Each share is represented by a restricted stock unit ("RSU") granted pursuant to the issuer's Non-Employee Director Compensation Policy and its 2021 Equity Incentive Plan. These RSUs vest on the earlier of July 10, 2027 or the date of the issuer's next Annual Meeting of Stockholders, subject to the Reporting Person continuing to provide services to the issuer.
F2Each share is represented by an additional RSU granted by the Board of Directors. These RSUs vest on the earlier of July 10, 2027 or the date of the issuer's next Annual Meeting of Stockholders, subject to the Reporting Person continuing to provide services to the issuer.
F3Consists of stock options granted pursuant to the issuer's Non-Employee Director Compensation Policy and its 2021 Equity Incentive Plan. These stock options vest over one year as follows: 1/12 of the original grant amount vests in monthly installments for one year following the grant date; provided, however, that the stock options shall be fully vested on the earlier of the first anniversary of the grant date or the date of the issuer's next Annual Meeting of Stockholders, subject to the Reporting Person continuing to provide services to the issuer.
F4These stock options vest over one year as follows: 1/12 of the original grant amount vests in monthly installments for one year following the grant date; provided, however, that the stock options shall be fully vested on the earlier of the first anniversary of the grant date or the date of the issuer's next Annual Meeting of Stockholders, subject to the Reporting Person continuing to provide services to the issuer.