Security	Date	Code	Shares	Price	A/D	Owned after	D/I	Nature of ownership
Common Stock^F1,F2,F7	Aug 28, 2015	S	20,689	$10.6412	D	4,026,013	I	See Footnote
Common Stock^F3,F4,F7	Aug 29, 2015	S	57,595	$10.3198	D	3,968,418	I	See Footnote
Common Stock^F5,F6,F7	Sep 1, 2015	S	42,983	$9.9655	D	3,925,435	I	See Footnote

Table II — derivative securities

No Table II lines on this filing.

Explanation of responses

F1Rho Ventures IV (QP), L.P. ("RV QP") sold 7,026 shares, Rho Ventures IV GmbH & Co. Beteiligungs KG ("RV KG") sold 7,322 shares, Rho Ventures IV Holdings LLC ("RV IV Holdings") sold 5,011 shares and Rho Ventures IV, L.P. ("RV IV LP") sold 1,330 shares.
F2Consists of 1,367,257 shares held by RV QP, 1,424,881 shares held by RV KG, 975,175 shares held by RV IV Holdings and 258,700 shares held by RV IV LP.
F3RV QP sold 19,559 shares, RV KG sold 20,383 shares, RV IV Holdings sold 13,950 shares and RV IV LP sold 3,703 shares.
F4Consists of 1,347,698 shares held by RV QP, 1,404,498 shares held by RV KG, 961,225 shares held by RV IV Holdings and 254,997 shares held by RV IV LP.
F5RV QP sold 14,597 shares, RV KG sold 15,212 shares, RV IV Holdings sold 10,410 shares and RV IV LP sold 2,764 shares.
F6Consists of 1,333,101 shares held by RV QP, 1,389,286 shares held by RV KG, 950,815 shares held by RV IV Holdings and 252,233 shares held by RV IV LP.
F7Rho Management Ventures IV, L.L.C. ("RMV") is the general partner of RV QP and RV IV LP and the managing member of RV IV Holdings, and Rho Capital Partners Verwaltings GmbH ("RCP Verwaltungs") is the general partner of RV KG. Each of RMV and RCP Verwaltungs disclaim beneficial ownership of the reportable securities and this report shall not be deemed an admission that RMV or RCP Verwaltungs is the beneficial owner of such securities, except to the extent of its pecuniary interest therein. Mark Leschly and Joshua Ruch are managing members of RMV and managing directors of RCP Verwaltungs. Each of Mark Leschly and Joshua Ruch disclaim beneficial ownership of the reportable securities and this report shall not be deemed an admission that any of them is the beneficial owner of such securities, except to the extent of his pecuniary interest therein.