Form4insider filings, from the source

SEC Form 4 · accession 0000315066-16-005625

PROTEOSTASIS THERAPEUTICS, INC. · PTI

Statement of changes in beneficial ownership, as filed. Original on EDGAR ↗

Reporting owner
FMR LLC
Other
Period of report
Feb 17, 2016
Accepted (ET)
Feb 18, 2016 · 2:00 pm EST
Rule 10b5-1 plan
unknown — predates the checkbox
Issuer CIK
0001445283

Table I — non-derivative securities

SecurityDateCodeSharesPriceA/DOwned afterD/INature of ownership
Common StockF1,F2Feb 17, 2016C925,051—A1,318,932IF-Prime Capital Partners Healthcare Fund II LP
Common StockF1Feb 17, 2016C183,880—A1,502,812IF-Prime Capital Partners Healthcare Fund II LP
Common StockFeb 17, 2016P375,000$8.00A1,877,812IF-Prime Capital Partners Healthcare Fund II LP

Table II — derivative securities

SecurityConv. / exercise priceDateCodeSharesA/DExercisableExpiresUnderlyingUnderlying sharesOwned afterD/I
Series A Convertible Preferred StockF1—Feb 17, 2016C10,000,000D——Common Stock925,0510I
Series B Convertible Preferred StockF1—Feb 17, 2016C1,987,782D——Common Stock183,8800I

Explanation of responses

Remarks

Remark 1: Abigail P. Johnson is a Director, the Vice Chairman, the Chief Executive Officer and the President of FMR LLC. Members of the Johnson family, including Abigail P. Johnson, are the predominant owners, directly or through trusts, of Series B voting common shares of FMR LLC, representing 49% of the voting power of FMR LLC. The Johnson family group and all other Series B shareholders have entered into a shareholders' voting agreement under which all Series B voting common shares will be voted in accordance with the majority vote of Series B voting common shares. Accordingly, through their ownership of voting common shares and the execution of the shareholders' voting agreement, members of the Johnson family may be deemed, under the Investment Company Act of 1940, to form a controlling group with respect to FMR LLC. The address of Abigail P. Johnson is c/o FMR LLC, 245 Summer Street, Boston, MA 02110. Remark 2: The general partner of F-Prime Capital Partners Healthcare Fund II LP is F-Prime Capital Partners Healthcare Advisors Fund II LP. F-Prime Capital Partners Healthcare Advisors Fund II LP is solely managed by Impresa Management LLC, its general partner and investment manager. Impresa Management LLC is owned, directly or indirectly, by various shareholders and employees of FMR LLC, including certain members of the Johnson family. Exhibit List: Exhibit 24 - Powers of Attorney.