Security	Date	Code	Shares	Price	A/D	Owned after	D/I
Common Stock^F1,F2,F3	Sep 24, 2018	S	200	$1.95	D	7,143,948	D
Common Stock^F1,F2,F3	Sep 25, 2018	S	17,078	$1.96	D	7,126,870	D
Common Stock^F1,F2,F3	Sep 26, 2018	S	300	$1.95	D	7,126,570	D
Common Stock^F1,F2,F3	Sep 26, 2018	P	2,000	$1.90	A	7,128,570	D

Table II — derivative securities

No Table II lines on this filing.

Explanation of responses

F1These securities are held by Van Herk Investments B.V., a private company with limited liability incorporated under the laws of the Netherlands ("VHI"). This statement is being filed by (i) VHI, (ii) Van Herk Private Equity Investments B.V., a private company with limited liability incorporated under the laws of the Netherlands ("VHPI"), (iii) Stichting Administratiekantoor Penulata, a foundation organized under the laws of the Netherlands ("Penulata"), (iv) Van Herk Management Services B.V., a private company with limited liability incorporated under the laws of the Netherlands ("VHMS"), (v) Onroerend Goed Beheer- en Beleggingsmaatschappij A. van Herk B.V., a private company with limited liability incorporated under the laws of the Netherlands ("OGBBA"), (vi) A. van Herk Holding B.V., a private company with limited liability incorporated under the laws of the Netherlands ("Holdings"), Footnote (1) continued in Footnote (2).
F2Footnote (2) continued from Footnote (1). (vii) Stichting Administratiekantoor Abchrys, a foundation organized under the laws of the Netherlands ("Abchrys"), and (viii) Adrianus van Herk ("Mr. van Herk"). Mr. van Herk is (i) an investor, (ii) the holder of all of the depositary receipts issued by Penulata and Abchrys, (iii) the sole board member of Penulata and Abchrys, and (iii) the sole managing director of VHMS, OGBBA and Holdings. Penulata holds substantially all of the issued and outstanding shares of VHPI. VHPI is the sole shareholder of VHI. VHI is principally engaged in making investments. Abchrys holds substantially all of the issued and outstanding shares of Holdings. Holdings is the sole shareholder of OGBBA. OGBBA is the sole shareholder of VHMS and is principally engaged in making investments. Footnote (2) continued in Footnote (3).
F3Footnote (3) continued from Footnote (2). VHMS is the sole managing director of VHI and VHPI. Each of Mr. van Herk, VHPI, Penulata, VHMS, OGBBA, Holdings and Abchrys disclaims beneficial ownership of the securities covered by this statement except to the extent of their pecuniary interest therein, if any, and this statement shall not be deemed an admission that any of them is a beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.

Remarks

* Pursuant to a Power of Attorney, dated as of February 27, 2018, by and among the Reporting Persons. Exhibit 24.1 Power of Attorney, dated as of February 27, 2018, by and among the Reporting Persons, incorporated herein by reference to Exhibit 3 to Schedule 13D/A filed by the Reporting Persons on March 13, 2018 with respect to Ablynx NV (File No. 005-90201).