Security	Date	Code	Shares	Price	A/D	Owned after	D/I	Nature of ownership
Common Stock^F3	Jan 6, 2015	J	6,952	$0.00	D	7,812	I	See Footnote
Common Stock^F5	Jan 6, 2015	J	778,272	$0.00	D	1,263,716	I	See Footnote
Common Stock^F6	Jan 6, 2015	J	136,039	$0.00	A	136,039	I	See Footnote
Common Stock^F6	Jan 7, 2015	J	136,039	$0.00	D	0	I	See Footnote
Common Stock^F8	Jan 7, 2015	J	17,832	$0.00	A	54,163	I	By Colella Family Partners and Colella Family Trust UTA Dated 9/21/92
Common Stock^F8	Jan 6, 2015	J	778	$0.00	A	54,941	I	By Collela Family Partners and Collela Family Trust UTA Dated 9/21/92
Common Stock^F10	Jan 7, 2015	J	17,832	$0.00	A	56,127	I	By Atwood Edminster Trust
Common Stock^F10	Jan 6, 2015	J	389	$0.00	A	56,516	I	By Atwood Edminster Trust
Common Stock^F11	Jan 7, 2015	J	17,832	$0.00	A	56,385	I	By The Jaffe Family Trust
Common Stock^F11	Jan 6, 2015	J	486	$0.00	A	56,871	I	By The Jaffe Family Trust
Common Stock^F12	Jan 7, 2015	J	17,832	$0.00	A	56,385	I	By The Link Family Trust
Common Stock^F12	Jan 6, 2015	J	486	$0.00	A	56,871	I	By The Link Family Trust
Common Stock^F13	Jan 7, 2015	J	4,459	$0.00	A	16,329	I	By Milder Community Property Trust
Common Stock^F13	Jan 6, 2015	J	972	$0.00	A	17,301	I	By Milder Community Property Trust
Common Stock^F1	holding	—	—		—	31,334	I	See Footnote

Table II — derivative securities

No Table II lines on this filing.

Explanation of responses

F1The shares are held by Versant Affiliates Fund II-A, L.P. ("VAF II-A"). Versant Ventures II, LLC ("VV II") serves as the sole general partner of VAF II-A. Brian G. Atwood, Samuel D. Colella, Ross A. Jaffe, William J. Link, Ph.D., Donald B. Milder, Rebecca B. Robertson, Bradley J. Bolzon, Charles M. Warden, and Barbara N. Lubash are directors and/or members of VV II and share voting and dispositive power over the shares held by VAF II-A, however, each disclaim beneficial ownership of these shares, except to the extent of their pecuniary interest in such shares.
F10The shares are held by the Atwood-Edminster Trust dated 4/2/2000 (the "Trust") for the benefit of Brian G. Atwood. Brian G. Atwood is a trustee of the Trust. The Reporting Person disclaims beneficial ownership of the shares except to the extent of his proportionate pecuniary interest therein.
F11The shares are held by the The Jaffe Family Trust (the "Trust") for the benefit of Ross A. Jaffe. Ross A. Jaffe is a trustee of the Trust. The Reporting Person disclaims beneficial ownership of the shares except to the extent of his proportionate pecuniary interest therein.
F12The shares are held by the The Link Family Trust (the "Trust") for the benefit of William J. Link. William J. Link is a trustee of the Trust. The Reporting Person disclaims beneficial ownership of the shares except to the extent of his proportionate pecuniary interest therein.
F13The shares are held by the Milder Community Property Trust (the "Trust") for the benefit of Donald B. Milder. Donald B. Milder is a trustee of the Trust. The Reporting Person disclaims beneficial ownership of the shares except to the extent of his proportionate pecuniary interest therein.
F2Represents a pro-rata in-kind distribution of Common Stock of the Issuer by Versant Side Fund II, L.P. ("VSF II") without consideration to its partners.
F3The shares are held by VSF II. VV II serves as the sole general partner of VSF II. Brian G. Atwood, Samuel D. Colella, Ross A. Jaffe, William J. Link, Ph.D., Donald B. Milder, Rebecca B. Robertson, Bradley J. Bolzon, Charles M. Warden, and Barbara N. Lubash are directors and/or members of VV II and share voting and dispositive power over the shares held by VSF II, however, each disclaim beneficial ownership of these shares, except to the extent of their pecuniary interest in such shares.
F4Represents a pro-rata in-kind distribution of Common Stock of the Issuer by Versant Venture Capital II, L.P. ("VVC II") without consideration to its partners.
F5The shares are held by VVC II. VV II serves as the sole general partner of VVC II. Brian G. Atwood, Samuel D. Colella, Ross A. Jaffe, William J. Link, Ph.D., Donald B. Milder, Rebecca B. Robertson, Bradley J. Bolzon, Charles M. Warden, and Barbara N. Lubash are directors and/or members of VV II and share voting and dispositive power over the shares held by VVC II, however, each disclaim beneficial ownership of these shares, except to the extent of their pecuniary interest in such shares.
F6The shares are held by VV II. Brian G. Atwood, Samuel D. Colella, Ross A. Jaffe, William J. Link, Ph.D., Donald B. Milder, Rebecca B. Robertson, Bradley J. Bolzon, Charles M. Warden, and Barbara N. Lubash are directors and/or members of VV II and share voting and dispositive power over the shares held by VV II, however, each disclaim beneficial ownership of these shares, except to the extent of their pecuniary interest in such shares.
F7Represents a pro-rata in-kind distribution of Common Stock of the Issuer by VV II without consideration to its members.
F8The shares are held by Colella Family Partners and Colella Family Trust UTA Dated 9/21/92 for the benefit of Samuel D. Colella. Samuel D. Colella is a general partner of Colella Family Partners and a trustee of Colella Family Trust UTA Dated 9/21/92. The Reporting Person disclaims beneficial ownership of the shares except to the extent of his proportionate pecuniary interest therein.
F9Represents a pro-rata in-kind distribution of Common Stock of the Issuer by VSF II without consideration to its partners.

Remarks

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