Security	Date	Code	Shares	Price	A/D	Owned after	D/I
Common Stock^F1,F2,F3	May 12, 2015	C	582,490	—	A	582,490	D
Common Stock^F1,F2,F3	May 12, 2015	C	222,231	—	A	804,721	D
Common Stock^F1,F2,F3	May 12, 2015	C	392,113	—	A	1,196,834	D
Common Stock^F1,F2,F3	May 12, 2015	C	540,498	—	A	1,737,332	D
Common Stock^F3	May 12, 2015	P	150,000	$12.00	A	1,887,332	D

Table II — derivative securities

Security	Conv. / exercise price	Date	Code	Shares	A/D	Exercisable	Expires	Underlying	Underlying shares	D/I
Series A Convertible Stock^F3,F1,F2	—	May 12, 2015	C	4,019,183	D	—	—	Common Stock	582,490	D
Series B Convertible Stock^F3,F1,F2	—	May 12, 2015	C	1,533,399	D	—	—	Common Stock	222,231	D
Series C Convertible Stock^F3,F1,F2	—	May 12, 2015	C	2,705,585	D	—	—	Common Stock	392,113	D
Series D Convertible Stock^F3,F1,F2	—	May 12, 2015	C	3,676,078	D	—	—	Common Stock	540,498	D

Explanation of responses

F1All series of Convertible Preferred Stock automatically converted into Collegium Pharmaceutical, Inc. common stock on a 1-for-6.9 basis immediately prior to the closing of the initial public offering and had no expiration date.
F2Reflects the conversion of preferred stock into Collegium Pharmaceutical, Inc. common stock on a 1-for-6.9 basis which became effective on May 12, 2015.
F3This report is filed jointly by Frazier Healthcare VI, L.P. ("FHVI"), FHM VI, L.P. ("FHM LP"), FHM VI, LLC ("FHM LLC"), Nathan Every ("Every"), Alan Frazier ("Frazier"), Patrick Heron ("Heron"), Nader Naini ("Naini") and James Topper ("Topper"). The shares are held by FHVI. The general partner of FHVI is FHM LP, a limited partnership, the general partner of which is FHM LLC. The members of FHM LLC are Every, Frazier, Naini, Heron, and Topper. These individuals share voting and investment power over the shares held by FHVI. Each of these individuals disclaims beneficial ownership of such shares, except to the extent of his pecuniary interest.