Security	Date	Code	Shares	Price	A/D	Owned after	D/I	Nature of ownership
Common Stock^F2	Jun 10, 2015	J	1,375,733	$0.00	D	4,127,232	I	By GPP-Connecture LLC
Common Stock^F3	Jun 10, 2015	J	39,703	$0.00	A	39,703	D
Common Stock^F4	Jun 10, 2015	J	36,493	$0.00	A	36,493	D
Common Stock^F5	Jun 10, 2015	J	47,235	$0.00	A	47,235	I	See Remarks
Common Stock^F6	Jun 10, 2015	J	28,696	$0.00	A	28,696	I	See Remarks

Table II — derivative securities

No Table II lines on this filing.

Explanation of responses

F1Represents shares of the issuer's common stock distributed pro rata by GPP - Connecture, LLC to its members.
F2Shares held directly by GPP-Connecture LLC ("GPPC"). Great Point Partners I GP, LLC is the general partner of Great Point Partners I, LP, which is the sole managing member of GPPC. Dr. Jeffrey R. Jay is the senior managing member, and David Kroin is the special managing member, of Great Point Partners LLC, which is the investment manager to Great Point Partners I, L.P. Each of Dr. Jay, Mr. Kroin, Great Point Partners LLC, Great Point Partners I GP, LLC and Great Point Partners I, LP may be deemed to have voting and dispositive power over the shares held by GPPC, and disclaim beneficial ownership of the shares held by GPPC, except to the extent of their pecuniary interest therein.
F3These shares are held directly by Mr. Kroin.
F4These shares are held directly by Dr. Jay.
F5Includes 11,341 shares held by a trust of which Dr. Jay is a trustee and of which beneficiaries may be considered members of Dr. Jay's immediate family, and 35,894 shares held by a trust of which Dr. Jay is the income beneficiary (but not the trustee). In each case Dr. Jay disclaims beneficial ownership of the shares except to the extent of his pecuniary interest therein.
F6Includes shares owned by Biomedical Offshore Value Fund, Ltd. ("BOVF"). Great Point Partners, LLC is the investment manager of BOVF, and by virtue of such status may be deemed to be the beneficial owner of the such shares. Each of Dr. Jay, as senior managing member of Great Point Partners, LLC, and Mr. Kroin, as special managing member of Great Point Partners, LLC, has voting and investment power with respect to such shares, and therefore may be deemed to be the beneficial owner of such shares. Each of Dr. Jay and Mr. Kroin disclaims beneficial ownership of such shares except to the extent of his pecuniary interest therein.